Sequence analysis of bitter taste receptor gene repertoires in different ruminant species
Bitter taste has been extensively studied in mammalian species and is associated with sensitivity to toxins and with food choices that avoid dangerous substances in the diet. At the molecular level, bitter compounds are sensed by bitter taste receptor proteins (T2R) present at the surface of taste r...
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2015
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Online Access: | http://hdl.handle.net/10174/19653 http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0124933 https://doi.org/10.1371/journal.pone.0124933 |
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ftunivevora:oai:dspace.uevora.pt:10174/19653 2023-09-05T13:21:09+02:00 Sequence analysis of bitter taste receptor gene repertoires in different ruminant species Ferreira, Ana Monteiro Marques, Andreia Tomás Bhide, Mangesh Cubric-Curik, Vlatka Hollung, Kristin Knight, Christopher Harold Raundrup, Katrine Lippolis, John Palmer, Mitchell Sales-Baptista, Elvira Araújo, Susana Sousa Almeida, André Martinho 2015 http://hdl.handle.net/10174/19653 http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0124933 https://doi.org/10.1371/journal.pone.0124933 por por http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0124933 http://hdl.handle.net/10174/19653 Departamento de Zootecnia nd 385 doi:10.1371/journal.pone.0124933 openAccess feeding strategy TAS2R diet selection bitter taste article 2015 ftunivevora https://doi.org/10.1371/journal.pone.0124933 2023-08-14T17:40:50Z Bitter taste has been extensively studied in mammalian species and is associated with sensitivity to toxins and with food choices that avoid dangerous substances in the diet. At the molecular level, bitter compounds are sensed by bitter taste receptor proteins (T2R) present at the surface of taste receptor cells in the gustatory papillae. Our work aims at exploring the phylogenetic relationships of T2R gene sequences within different ruminant species. To accomplish this goal, we gathered a collection of ruminant species with different feeding behaviors and for which no genome data is available: American bison, chamois, elk, European bison, fallow deer, goat, moose, mouflon, muskox, red deer, reindeer and white tailed deer. The herbivores chosen for this study belong to different taxonomic families and habitats, and hence, exhibit distinct foraging behaviors and diet preferences. We describe the first partial repertoires of T2R gene sequences for these species obtained by direct sequencing. We then consider the homology and evolutionary history of these receptors within this ruminant group, and whether it relates to feeding type classification, using MEGA software. Our results suggest that phylogenetic proximity of T2R genes corresponds more to the traditional taxonomic groups of the species rather than reflecting a categorization by feeding strategy. Article in Journal/Newspaper muskox Repositório Científico da Universidade de Évora PLOS ONE 10 6 e0124933 |
institution |
Open Polar |
collection |
Repositório Científico da Universidade de Évora |
op_collection_id |
ftunivevora |
language |
Portuguese |
topic |
feeding strategy TAS2R diet selection bitter taste |
spellingShingle |
feeding strategy TAS2R diet selection bitter taste Ferreira, Ana Monteiro Marques, Andreia Tomás Bhide, Mangesh Cubric-Curik, Vlatka Hollung, Kristin Knight, Christopher Harold Raundrup, Katrine Lippolis, John Palmer, Mitchell Sales-Baptista, Elvira Araújo, Susana Sousa Almeida, André Martinho Sequence analysis of bitter taste receptor gene repertoires in different ruminant species |
topic_facet |
feeding strategy TAS2R diet selection bitter taste |
description |
Bitter taste has been extensively studied in mammalian species and is associated with sensitivity to toxins and with food choices that avoid dangerous substances in the diet. At the molecular level, bitter compounds are sensed by bitter taste receptor proteins (T2R) present at the surface of taste receptor cells in the gustatory papillae. Our work aims at exploring the phylogenetic relationships of T2R gene sequences within different ruminant species. To accomplish this goal, we gathered a collection of ruminant species with different feeding behaviors and for which no genome data is available: American bison, chamois, elk, European bison, fallow deer, goat, moose, mouflon, muskox, red deer, reindeer and white tailed deer. The herbivores chosen for this study belong to different taxonomic families and habitats, and hence, exhibit distinct foraging behaviors and diet preferences. We describe the first partial repertoires of T2R gene sequences for these species obtained by direct sequencing. We then consider the homology and evolutionary history of these receptors within this ruminant group, and whether it relates to feeding type classification, using MEGA software. Our results suggest that phylogenetic proximity of T2R genes corresponds more to the traditional taxonomic groups of the species rather than reflecting a categorization by feeding strategy. |
format |
Article in Journal/Newspaper |
author |
Ferreira, Ana Monteiro Marques, Andreia Tomás Bhide, Mangesh Cubric-Curik, Vlatka Hollung, Kristin Knight, Christopher Harold Raundrup, Katrine Lippolis, John Palmer, Mitchell Sales-Baptista, Elvira Araújo, Susana Sousa Almeida, André Martinho |
author_facet |
Ferreira, Ana Monteiro Marques, Andreia Tomás Bhide, Mangesh Cubric-Curik, Vlatka Hollung, Kristin Knight, Christopher Harold Raundrup, Katrine Lippolis, John Palmer, Mitchell Sales-Baptista, Elvira Araújo, Susana Sousa Almeida, André Martinho |
author_sort |
Ferreira, Ana Monteiro |
title |
Sequence analysis of bitter taste receptor gene repertoires in different ruminant species |
title_short |
Sequence analysis of bitter taste receptor gene repertoires in different ruminant species |
title_full |
Sequence analysis of bitter taste receptor gene repertoires in different ruminant species |
title_fullStr |
Sequence analysis of bitter taste receptor gene repertoires in different ruminant species |
title_full_unstemmed |
Sequence analysis of bitter taste receptor gene repertoires in different ruminant species |
title_sort |
sequence analysis of bitter taste receptor gene repertoires in different ruminant species |
publishDate |
2015 |
url |
http://hdl.handle.net/10174/19653 http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0124933 https://doi.org/10.1371/journal.pone.0124933 |
genre |
muskox |
genre_facet |
muskox |
op_relation |
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0124933 http://hdl.handle.net/10174/19653 Departamento de Zootecnia nd 385 doi:10.1371/journal.pone.0124933 |
op_rights |
openAccess |
op_doi |
https://doi.org/10.1371/journal.pone.0124933 |
container_title |
PLOS ONE |
container_volume |
10 |
container_issue |
6 |
container_start_page |
e0124933 |
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1776201756898754560 |