Aquatic Pollution and Risks to Biodiversity: The Example of Cocaine Effects on the Ovaries of Anguilla anguilla
Pollution is one of the main causes of the loss of biodiversity, currently one of the most important environmental problems. Important sources of aquatic pollution are illicit drugs, whose presence in waters is closely related to human consumption; their psychoactive properties and biological activi...
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Online Access: | http://hdl.handle.net/11449/241518 https://doi.org/10.3390/ani12141766 |
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ftunivespir:oai:repositorio.unesp.br:11449/241518 2023-07-02T03:29:35+02:00 Aquatic Pollution and Risks to Biodiversity: The Example of Cocaine Effects on the Ovaries of Anguilla anguilla Fontes, Mayana Karoline Rosati, Luigi Di Lorenzo, Mariana Pereira, Camilo Dias Seabra Maranho, Luciane Alves Laforgia, Vincenza Capaldo, Anna Universidade Estadual Paulista (UNESP) 2022-07-01 http://hdl.handle.net/11449/241518 https://doi.org/10.3390/ani12141766 eng eng Animals http://dx.doi.org/10.3390/ani12141766 Animals, v. 12, n. 14, 2022. 2076-2615 http://hdl.handle.net/11449/241518 doi:10.3390/ani12141766 2-s2.0-85136162407 Anguilla anguilla cocaine gonadotropins oogenesis enzymes ovary info:eu-repo/semantics/article 2022 ftunivespir https://doi.org/10.3390/ani12141766 2023-06-12T17:45:41Z Pollution is one of the main causes of the loss of biodiversity, currently one of the most important environmental problems. Important sources of aquatic pollution are illicit drugs, whose presence in waters is closely related to human consumption; their psychoactive properties and biological activity suggest potential adverse effects on non-target organisms, such as aquatic biota. In this study, we evaluated the effect of an environmentally relevant concentration of cocaine (20 ng L−1), an illicit drug widely found in surface waters, on the ovaries of Anguilla anguilla, a species critically endangered and able to accumulate cocaine in its tissues following chronic exposure. The following parameters were evaluated: (1) the morphology of the ovaries; (2) the presence and distribution of enzymes involved in oogenesis; (3) serum cortisol, FSH, and LH levels. The eels exposed to cocaine showed a smaller follicular area and a higher percentage of connective tissue than controls (p < 0.05), as well as many previtellogenic oocytes compared with controls having numerous fully vitellogenic and early vitellogenic oocytes. In addition, the presence and location of 3β-hydroxysteroid dehydrogenase, 17β-hydroxysteroid dehydrogenase, and P450 aromatase differed in the two groups. Finally, cocaine exposure decreased FSH and LH levels, while it increased cortisol levels. These findings show that even a low environmental concentration of cocaine affects the ovarian morphology and activity of A. anguilla, suggesting a potential impact on reproduction in this species. Article in Journal/Newspaper Anguilla anguilla Universidade Estadual Paulista São Paulo: Repositório Institucional UNESP Animals 12 14 1766 |
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Universidade Estadual Paulista São Paulo: Repositório Institucional UNESP |
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language |
English |
topic |
Anguilla anguilla cocaine gonadotropins oogenesis enzymes ovary |
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Anguilla anguilla cocaine gonadotropins oogenesis enzymes ovary Fontes, Mayana Karoline Rosati, Luigi Di Lorenzo, Mariana Pereira, Camilo Dias Seabra Maranho, Luciane Alves Laforgia, Vincenza Capaldo, Anna Aquatic Pollution and Risks to Biodiversity: The Example of Cocaine Effects on the Ovaries of Anguilla anguilla |
topic_facet |
Anguilla anguilla cocaine gonadotropins oogenesis enzymes ovary |
description |
Pollution is one of the main causes of the loss of biodiversity, currently one of the most important environmental problems. Important sources of aquatic pollution are illicit drugs, whose presence in waters is closely related to human consumption; their psychoactive properties and biological activity suggest potential adverse effects on non-target organisms, such as aquatic biota. In this study, we evaluated the effect of an environmentally relevant concentration of cocaine (20 ng L−1), an illicit drug widely found in surface waters, on the ovaries of Anguilla anguilla, a species critically endangered and able to accumulate cocaine in its tissues following chronic exposure. The following parameters were evaluated: (1) the morphology of the ovaries; (2) the presence and distribution of enzymes involved in oogenesis; (3) serum cortisol, FSH, and LH levels. The eels exposed to cocaine showed a smaller follicular area and a higher percentage of connective tissue than controls (p < 0.05), as well as many previtellogenic oocytes compared with controls having numerous fully vitellogenic and early vitellogenic oocytes. In addition, the presence and location of 3β-hydroxysteroid dehydrogenase, 17β-hydroxysteroid dehydrogenase, and P450 aromatase differed in the two groups. Finally, cocaine exposure decreased FSH and LH levels, while it increased cortisol levels. These findings show that even a low environmental concentration of cocaine affects the ovarian morphology and activity of A. anguilla, suggesting a potential impact on reproduction in this species. |
author2 |
Universidade Estadual Paulista (UNESP) |
format |
Article in Journal/Newspaper |
author |
Fontes, Mayana Karoline Rosati, Luigi Di Lorenzo, Mariana Pereira, Camilo Dias Seabra Maranho, Luciane Alves Laforgia, Vincenza Capaldo, Anna |
author_facet |
Fontes, Mayana Karoline Rosati, Luigi Di Lorenzo, Mariana Pereira, Camilo Dias Seabra Maranho, Luciane Alves Laforgia, Vincenza Capaldo, Anna |
author_sort |
Fontes, Mayana Karoline |
title |
Aquatic Pollution and Risks to Biodiversity: The Example of Cocaine Effects on the Ovaries of Anguilla anguilla |
title_short |
Aquatic Pollution and Risks to Biodiversity: The Example of Cocaine Effects on the Ovaries of Anguilla anguilla |
title_full |
Aquatic Pollution and Risks to Biodiversity: The Example of Cocaine Effects on the Ovaries of Anguilla anguilla |
title_fullStr |
Aquatic Pollution and Risks to Biodiversity: The Example of Cocaine Effects on the Ovaries of Anguilla anguilla |
title_full_unstemmed |
Aquatic Pollution and Risks to Biodiversity: The Example of Cocaine Effects on the Ovaries of Anguilla anguilla |
title_sort |
aquatic pollution and risks to biodiversity: the example of cocaine effects on the ovaries of anguilla anguilla |
publishDate |
2022 |
url |
http://hdl.handle.net/11449/241518 https://doi.org/10.3390/ani12141766 |
genre |
Anguilla anguilla |
genre_facet |
Anguilla anguilla |
op_relation |
Animals http://dx.doi.org/10.3390/ani12141766 Animals, v. 12, n. 14, 2022. 2076-2615 http://hdl.handle.net/11449/241518 doi:10.3390/ani12141766 2-s2.0-85136162407 |
op_doi |
https://doi.org/10.3390/ani12141766 |
container_title |
Animals |
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12 |
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14 |
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1766 |
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1770275469295353856 |