Metabolomic Profile of the Fungus Cryomyces antarcticus Under Simulated Martian and Space Conditions as Support for Life-Detection Missions on Mars
The identification of traces of life beyond Earth (e.g., Mars, icy moons) is a challenging task because terrestrial chemical-based molecules may be destroyed by the harsh conditions experienced on extraterrestrial planetary surfaces. For this reason, studying the effects on biomolecules of extremoph...
Published in: | Frontiers in Microbiology |
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Online Access: | https://hdl.handle.net/10278/5033163 https://doi.org/10.3389/fmicb.2022.749396 |
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ftuniveneziairis:oai:iris.unive.it:10278/5033163 2024-04-14T08:03:52+00:00 Metabolomic Profile of the Fungus Cryomyces antarcticus Under Simulated Martian and Space Conditions as Support for Life-Detection Missions on Mars Gevi, F. Leo, P. Cassaro, A. Pacelli, C. de Vera, J. -P. P. Rabbow, E. Timperio, A. M. Onofri, S. Gevi, F. Leo, P. Cassaro, A. Pacelli, C. de Vera, J. -P. P. Rabbow, E. Timperio, A. M. Onofri, S. 2022 https://hdl.handle.net/10278/5033163 https://doi.org/10.3389/fmicb.2022.749396 eng eng info:eu-repo/semantics/altIdentifier/pmid/35633719 info:eu-repo/semantics/altIdentifier/wos/WOS:000802178500001 volume:13 firstpage:749396 journal:FRONTIERS IN MICROBIOLOGY https://hdl.handle.net/10278/5033163 doi:10.3389/fmicb.2022.749396 info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85131214532 LC-MS biosignature extremophilic microorganism metabolite osmolyte stress resistance Settore BIO/10 - Biochimica Settore BIO/11 - Biologia Molecolare Settore BIO/19 - Microbiologia Generale info:eu-repo/semantics/article 2022 ftuniveneziairis https://doi.org/10.3389/fmicb.2022.749396 2024-03-21T17:57:10Z The identification of traces of life beyond Earth (e.g., Mars, icy moons) is a challenging task because terrestrial chemical-based molecules may be destroyed by the harsh conditions experienced on extraterrestrial planetary surfaces. For this reason, studying the effects on biomolecules of extremophilic microorganisms through astrobiological ground-based space simulation experiments is significant to support the interpretation of the data that will be gained and collected during the ongoing and future space exploration missions. Here, the stability of the biomolecules of the cryptoendolithic black fungus Cryomyces antarcticus, grown on two Martian regolith analogues and on Antarctic sandstone, were analysed through a metabolomic approach, after its exposure to Science Verification Tests (SVTs) performed in the frame of the European Space Agency (ESA) Biology and Mars Experiment (BIOMEX) project. These tests are building a set of ground-based experiments performed before the space exposure aboard the International Space Station (ISS). The analysis aimed to investigate the effects of different mineral mixtures on fungal colonies and the stability of the biomolecules synthetised by the fungus under simulated Martian and space conditions. The identification of a specific group of molecules showing good stability after the treatments allow the creation of a molecular database that should support the analysis of future data sets that will be collected in the ongoing and next space exploration missions. Article in Journal/Newspaper Antarc* Antarctic antarcticus Università Ca’ Foscari Venezia: ARCA (Archivio Istituzionale della Ricerca) Antarctic Frontiers in Microbiology 13 |
institution |
Open Polar |
collection |
Università Ca’ Foscari Venezia: ARCA (Archivio Istituzionale della Ricerca) |
op_collection_id |
ftuniveneziairis |
language |
English |
topic |
LC-MS biosignature extremophilic microorganism metabolite osmolyte stress resistance Settore BIO/10 - Biochimica Settore BIO/11 - Biologia Molecolare Settore BIO/19 - Microbiologia Generale |
spellingShingle |
LC-MS biosignature extremophilic microorganism metabolite osmolyte stress resistance Settore BIO/10 - Biochimica Settore BIO/11 - Biologia Molecolare Settore BIO/19 - Microbiologia Generale Gevi, F. Leo, P. Cassaro, A. Pacelli, C. de Vera, J. -P. P. Rabbow, E. Timperio, A. M. Onofri, S. Metabolomic Profile of the Fungus Cryomyces antarcticus Under Simulated Martian and Space Conditions as Support for Life-Detection Missions on Mars |
topic_facet |
LC-MS biosignature extremophilic microorganism metabolite osmolyte stress resistance Settore BIO/10 - Biochimica Settore BIO/11 - Biologia Molecolare Settore BIO/19 - Microbiologia Generale |
description |
The identification of traces of life beyond Earth (e.g., Mars, icy moons) is a challenging task because terrestrial chemical-based molecules may be destroyed by the harsh conditions experienced on extraterrestrial planetary surfaces. For this reason, studying the effects on biomolecules of extremophilic microorganisms through astrobiological ground-based space simulation experiments is significant to support the interpretation of the data that will be gained and collected during the ongoing and future space exploration missions. Here, the stability of the biomolecules of the cryptoendolithic black fungus Cryomyces antarcticus, grown on two Martian regolith analogues and on Antarctic sandstone, were analysed through a metabolomic approach, after its exposure to Science Verification Tests (SVTs) performed in the frame of the European Space Agency (ESA) Biology and Mars Experiment (BIOMEX) project. These tests are building a set of ground-based experiments performed before the space exposure aboard the International Space Station (ISS). The analysis aimed to investigate the effects of different mineral mixtures on fungal colonies and the stability of the biomolecules synthetised by the fungus under simulated Martian and space conditions. The identification of a specific group of molecules showing good stability after the treatments allow the creation of a molecular database that should support the analysis of future data sets that will be collected in the ongoing and next space exploration missions. |
author2 |
Gevi, F. Leo, P. Cassaro, A. Pacelli, C. de Vera, J. -P. P. Rabbow, E. Timperio, A. M. Onofri, S. |
format |
Article in Journal/Newspaper |
author |
Gevi, F. Leo, P. Cassaro, A. Pacelli, C. de Vera, J. -P. P. Rabbow, E. Timperio, A. M. Onofri, S. |
author_facet |
Gevi, F. Leo, P. Cassaro, A. Pacelli, C. de Vera, J. -P. P. Rabbow, E. Timperio, A. M. Onofri, S. |
author_sort |
Gevi, F. |
title |
Metabolomic Profile of the Fungus Cryomyces antarcticus Under Simulated Martian and Space Conditions as Support for Life-Detection Missions on Mars |
title_short |
Metabolomic Profile of the Fungus Cryomyces antarcticus Under Simulated Martian and Space Conditions as Support for Life-Detection Missions on Mars |
title_full |
Metabolomic Profile of the Fungus Cryomyces antarcticus Under Simulated Martian and Space Conditions as Support for Life-Detection Missions on Mars |
title_fullStr |
Metabolomic Profile of the Fungus Cryomyces antarcticus Under Simulated Martian and Space Conditions as Support for Life-Detection Missions on Mars |
title_full_unstemmed |
Metabolomic Profile of the Fungus Cryomyces antarcticus Under Simulated Martian and Space Conditions as Support for Life-Detection Missions on Mars |
title_sort |
metabolomic profile of the fungus cryomyces antarcticus under simulated martian and space conditions as support for life-detection missions on mars |
publishDate |
2022 |
url |
https://hdl.handle.net/10278/5033163 https://doi.org/10.3389/fmicb.2022.749396 |
geographic |
Antarctic |
geographic_facet |
Antarctic |
genre |
Antarc* Antarctic antarcticus |
genre_facet |
Antarc* Antarctic antarcticus |
op_relation |
info:eu-repo/semantics/altIdentifier/pmid/35633719 info:eu-repo/semantics/altIdentifier/wos/WOS:000802178500001 volume:13 firstpage:749396 journal:FRONTIERS IN MICROBIOLOGY https://hdl.handle.net/10278/5033163 doi:10.3389/fmicb.2022.749396 info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85131214532 |
op_doi |
https://doi.org/10.3389/fmicb.2022.749396 |
container_title |
Frontiers in Microbiology |
container_volume |
13 |
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1796300177353474048 |