Collagen-based bioactive bromelain hydrolysate from salt-cured cod skin
Considerable amounts of fish processing by-products are discarded each year. About 30% of this material may be skin and bone. Fish skin has more than 80% of its total protein content as collagen. Furthermore, in recent years, there has been a growing demand for collagen-based peptides due to their b...
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Online Access: | http://hdl.handle.net/10400.14/34996 https://doi.org/10.3390/app11188538 |
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ftunivcplisboa:oai:repositorio.ucp.pt:10400.14/34996 2023-05-15T15:27:27+02:00 Collagen-based bioactive bromelain hydrolysate from salt-cured cod skin Coscueta, Ezequiel R. Brassesco, Maria Emilia Pintado, Manuela 2021-09-20T11:33:53Z http://hdl.handle.net/10400.14/34996 https://doi.org/10.3390/app11188538 eng eng 2076-3417 http://hdl.handle.net/10400.14/34996 doi:10.3390/app11188538 85115099262 000699716400001 openAccess http://creativecommons.org/licenses/by/4.0/ CC-BY Atlantic cod skin Enzymatic hydrolysis Collagen Fishery by-products Bioactive peptides Bromelain Antioxidant Antihypertensive article 2021 ftunivcplisboa https://doi.org/10.3390/app11188538 2021-10-13T00:01:15Z Considerable amounts of fish processing by-products are discarded each year. About 30% of this material may be skin and bone. Fish skin has more than 80% of its total protein content as collagen. Furthermore, in recent years, there has been a growing demand for collagen-based peptides due to their beneficial health effects. So, the objective of the present study was to optimise the obtaining bioactive hydrolysates from salt-cured cod skin using the protease Bromelain at 0.5% (w/w) concentration. This study developed a sustainable process that consumes less time and energy and uses an alternative source as raw material. In addition, bromelain allows hydrolysates with important antioxidant (ORAC, 514 μmol Trolox Equivalent/g protein) and antihypertensive activities (inhibition of ACE, IC50 of 166 μg protein/mL) as well as excellent biocompatibility with dermal and subcutaneous cells. info:eu-repo/semantics/publishedVersion Article in Journal/Newspaper atlantic cod Universidade Católica Portuguesa: Veritati - Repositório Institucional Applied Sciences 11 18 8538 |
institution |
Open Polar |
collection |
Universidade Católica Portuguesa: Veritati - Repositório Institucional |
op_collection_id |
ftunivcplisboa |
language |
English |
topic |
Atlantic cod skin Enzymatic hydrolysis Collagen Fishery by-products Bioactive peptides Bromelain Antioxidant Antihypertensive |
spellingShingle |
Atlantic cod skin Enzymatic hydrolysis Collagen Fishery by-products Bioactive peptides Bromelain Antioxidant Antihypertensive Coscueta, Ezequiel R. Brassesco, Maria Emilia Pintado, Manuela Collagen-based bioactive bromelain hydrolysate from salt-cured cod skin |
topic_facet |
Atlantic cod skin Enzymatic hydrolysis Collagen Fishery by-products Bioactive peptides Bromelain Antioxidant Antihypertensive |
description |
Considerable amounts of fish processing by-products are discarded each year. About 30% of this material may be skin and bone. Fish skin has more than 80% of its total protein content as collagen. Furthermore, in recent years, there has been a growing demand for collagen-based peptides due to their beneficial health effects. So, the objective of the present study was to optimise the obtaining bioactive hydrolysates from salt-cured cod skin using the protease Bromelain at 0.5% (w/w) concentration. This study developed a sustainable process that consumes less time and energy and uses an alternative source as raw material. In addition, bromelain allows hydrolysates with important antioxidant (ORAC, 514 μmol Trolox Equivalent/g protein) and antihypertensive activities (inhibition of ACE, IC50 of 166 μg protein/mL) as well as excellent biocompatibility with dermal and subcutaneous cells. info:eu-repo/semantics/publishedVersion |
format |
Article in Journal/Newspaper |
author |
Coscueta, Ezequiel R. Brassesco, Maria Emilia Pintado, Manuela |
author_facet |
Coscueta, Ezequiel R. Brassesco, Maria Emilia Pintado, Manuela |
author_sort |
Coscueta, Ezequiel R. |
title |
Collagen-based bioactive bromelain hydrolysate from salt-cured cod skin |
title_short |
Collagen-based bioactive bromelain hydrolysate from salt-cured cod skin |
title_full |
Collagen-based bioactive bromelain hydrolysate from salt-cured cod skin |
title_fullStr |
Collagen-based bioactive bromelain hydrolysate from salt-cured cod skin |
title_full_unstemmed |
Collagen-based bioactive bromelain hydrolysate from salt-cured cod skin |
title_sort |
collagen-based bioactive bromelain hydrolysate from salt-cured cod skin |
publishDate |
2021 |
url |
http://hdl.handle.net/10400.14/34996 https://doi.org/10.3390/app11188538 |
genre |
atlantic cod |
genre_facet |
atlantic cod |
op_relation |
2076-3417 http://hdl.handle.net/10400.14/34996 doi:10.3390/app11188538 85115099262 000699716400001 |
op_rights |
openAccess http://creativecommons.org/licenses/by/4.0/ |
op_rightsnorm |
CC-BY |
op_doi |
https://doi.org/10.3390/app11188538 |
container_title |
Applied Sciences |
container_volume |
11 |
container_issue |
18 |
container_start_page |
8538 |
_version_ |
1766357892730978304 |