First molecular detection and characterization of herpesvirus and poxvirus in a Pacific walrus (Odobenus rosmarus divergens)
BACKGROUND Herpesvirus and poxvirus can infect a wide range of species: herpesvirus genetic material has been detected and amplified in five species of the superfamily Pinnipedia; poxvirus genetic material, in eight species of Pinnipedia. To date, however, genetic material of these viruses has not b...
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ftunivcmadrid:oai:docta.ucm.es:20.500.14352/35272 2024-05-12T08:03:12+00:00 First molecular detection and characterization of herpesvirus and poxvirus in a Pacific walrus (Odobenus rosmarus divergens) Melero Asensio, Mar García Párraga, Daniel Corpa, Juan Manuel Ortega, Joaquín Rubio Guerri, Consuelo Crespo, José Luis Rivera Arroyo, Belén Sánchez-Vizcaíno Rodríguez, José Manuel 2014-12-21 application/pdf https://hdl.handle.net/20.500.14352/35272 https://doi.org/10.1186/s12917-014-0308-2 http://bmcvetres.biomedcentral.com/articles/10.1186/s12917-014-0308-2 eng eng BioMedCentral https://hdl.handle.net/20.500.14352/35272 1746-6148 doi:10.1186/s12917-014-0308-2 http://bmcvetres.biomedcentral.com/articles/10.1186/s12917-014-0308-2 Atribución 3.0 España https://creativecommons.org/licenses/by/3.0/es/ open access Herpesvirus Poxvirus Walrus Pinniped Veterinaria 3109 Ciencias Veterinarias journal article 2014 ftunivcmadrid https://doi.org/20.500.14352/3527210.1186/s12917-014-0308-2 2024-04-17T14:03:29Z BACKGROUND Herpesvirus and poxvirus can infect a wide range of species: herpesvirus genetic material has been detected and amplified in five species of the superfamily Pinnipedia; poxvirus genetic material, in eight species of Pinnipedia. To date, however, genetic material of these viruses has not been detected in walrus (Odobenus rosmarus), another marine mammal of the Pinnipedia clade, even though anti-herpesvirus antibodies have been detected in these animals. CASE PRESENTATION In February 2013, a 9-year-old healthy captive female Pacific walrus died unexpectedly at L'Oceanografic (Valencia, Spain). Herpesvirus was detected in pharyngeal tonsil tissue by PCR. Phylogenetic analysis revealed that the virus belongs to the subfamily Gammaherpesvirinae. Poxvirus was also detected by PCR in skin, pre-scapular and tracheobronchial lymph nodes and tonsils. Gross lesions were not detected in any tissue, but histopathological analyses of pharyngeal tonsils and lymph nodes revealed remarkable lymphoid depletion and lymphocytolysis. Similar histopathological lesions have been previously described in bovine calves infected with an alphaherpesvirus, and in northern elephant seals infected with a gammaherpesvirus that is closely related to the herpesvirus found in this case. Intracytoplasmic eosinophilic inclusion bodies, consistent with poxviral infection, were also observed in the epithelium of the tonsilar mucosa. CONCLUSION To our knowledge, this is the first molecular identification of herpesvirus and poxvirus in a walrus. Neither virus was likely to have contributed directly to the death of our animal. Centro de Vigilancia Sanitaria Veterinaria (VISAVET) TRUE pub Article in Journal/Newspaper Elephant Seals Odobenus rosmarus walrus* Docta Complutense (Universidad Complutense de Madrid - UCM) Pacific BMC Veterinary Research 10 1 |
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Open Polar |
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Docta Complutense (Universidad Complutense de Madrid - UCM) |
op_collection_id |
ftunivcmadrid |
language |
English |
topic |
Herpesvirus Poxvirus Walrus Pinniped Veterinaria 3109 Ciencias Veterinarias |
spellingShingle |
Herpesvirus Poxvirus Walrus Pinniped Veterinaria 3109 Ciencias Veterinarias Melero Asensio, Mar García Párraga, Daniel Corpa, Juan Manuel Ortega, Joaquín Rubio Guerri, Consuelo Crespo, José Luis Rivera Arroyo, Belén Sánchez-Vizcaíno Rodríguez, José Manuel First molecular detection and characterization of herpesvirus and poxvirus in a Pacific walrus (Odobenus rosmarus divergens) |
topic_facet |
Herpesvirus Poxvirus Walrus Pinniped Veterinaria 3109 Ciencias Veterinarias |
description |
BACKGROUND Herpesvirus and poxvirus can infect a wide range of species: herpesvirus genetic material has been detected and amplified in five species of the superfamily Pinnipedia; poxvirus genetic material, in eight species of Pinnipedia. To date, however, genetic material of these viruses has not been detected in walrus (Odobenus rosmarus), another marine mammal of the Pinnipedia clade, even though anti-herpesvirus antibodies have been detected in these animals. CASE PRESENTATION In February 2013, a 9-year-old healthy captive female Pacific walrus died unexpectedly at L'Oceanografic (Valencia, Spain). Herpesvirus was detected in pharyngeal tonsil tissue by PCR. Phylogenetic analysis revealed that the virus belongs to the subfamily Gammaherpesvirinae. Poxvirus was also detected by PCR in skin, pre-scapular and tracheobronchial lymph nodes and tonsils. Gross lesions were not detected in any tissue, but histopathological analyses of pharyngeal tonsils and lymph nodes revealed remarkable lymphoid depletion and lymphocytolysis. Similar histopathological lesions have been previously described in bovine calves infected with an alphaherpesvirus, and in northern elephant seals infected with a gammaherpesvirus that is closely related to the herpesvirus found in this case. Intracytoplasmic eosinophilic inclusion bodies, consistent with poxviral infection, were also observed in the epithelium of the tonsilar mucosa. CONCLUSION To our knowledge, this is the first molecular identification of herpesvirus and poxvirus in a walrus. Neither virus was likely to have contributed directly to the death of our animal. Centro de Vigilancia Sanitaria Veterinaria (VISAVET) TRUE pub |
format |
Article in Journal/Newspaper |
author |
Melero Asensio, Mar García Párraga, Daniel Corpa, Juan Manuel Ortega, Joaquín Rubio Guerri, Consuelo Crespo, José Luis Rivera Arroyo, Belén Sánchez-Vizcaíno Rodríguez, José Manuel |
author_facet |
Melero Asensio, Mar García Párraga, Daniel Corpa, Juan Manuel Ortega, Joaquín Rubio Guerri, Consuelo Crespo, José Luis Rivera Arroyo, Belén Sánchez-Vizcaíno Rodríguez, José Manuel |
author_sort |
Melero Asensio, Mar |
title |
First molecular detection and characterization of herpesvirus and poxvirus in a Pacific walrus (Odobenus rosmarus divergens) |
title_short |
First molecular detection and characterization of herpesvirus and poxvirus in a Pacific walrus (Odobenus rosmarus divergens) |
title_full |
First molecular detection and characterization of herpesvirus and poxvirus in a Pacific walrus (Odobenus rosmarus divergens) |
title_fullStr |
First molecular detection and characterization of herpesvirus and poxvirus in a Pacific walrus (Odobenus rosmarus divergens) |
title_full_unstemmed |
First molecular detection and characterization of herpesvirus and poxvirus in a Pacific walrus (Odobenus rosmarus divergens) |
title_sort |
first molecular detection and characterization of herpesvirus and poxvirus in a pacific walrus (odobenus rosmarus divergens) |
publisher |
BioMedCentral |
publishDate |
2014 |
url |
https://hdl.handle.net/20.500.14352/35272 https://doi.org/10.1186/s12917-014-0308-2 http://bmcvetres.biomedcentral.com/articles/10.1186/s12917-014-0308-2 |
geographic |
Pacific |
geographic_facet |
Pacific |
genre |
Elephant Seals Odobenus rosmarus walrus* |
genre_facet |
Elephant Seals Odobenus rosmarus walrus* |
op_relation |
https://hdl.handle.net/20.500.14352/35272 1746-6148 doi:10.1186/s12917-014-0308-2 http://bmcvetres.biomedcentral.com/articles/10.1186/s12917-014-0308-2 |
op_rights |
Atribución 3.0 España https://creativecommons.org/licenses/by/3.0/es/ open access |
op_doi |
https://doi.org/20.500.14352/3527210.1186/s12917-014-0308-2 |
container_title |
BMC Veterinary Research |
container_volume |
10 |
container_issue |
1 |
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1798845303914233856 |