Vertebral Column Deformity and hypoxia in Salmo salar Hipoxia relacionada a deformidad de columna vertebral en Salmo salar
Vertebral Column Deformity (VCD) is a common pathology in Chilean salmon farms, lowering the quality and commercialization of the product. Hypoxia has been related to other musculoskeletal deformities, but not to VCD. This work analyzes the morphology of the vertebral column of Salmo salar alevins,...
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ftunivchile:oai:repositorio.uchile.cl:2250/165503 2023-05-15T18:09:42+02:00 Vertebral Column Deformity and hypoxia in Salmo salar Hipoxia relacionada a deformidad de columna vertebral en Salmo salar Sánchez, Rodrigo Castro Obregón, Eduardo Bustos Rauco, Mariana Rojas 2011 application/pdf https://repositorio.uchile.cl/handle/2250/165503 en eng International Journal of Morphology, Volumen 29, Issue 4, 2018, Pages 1291-1295 07179367 07179502 https://repositorio.uchile.cl/handle/2250/165503 Attribution-NonCommercial-NoDerivs 3.0 Chile http://creativecommons.org/licenses/by-nc-nd/3.0/cl/ CC-BY-NC-ND International Journal of Morphology Deformity Hypoxia Salmon Vertebral column Artículo de revista 2011 ftunivchile 2023-01-22T00:53:10Z Vertebral Column Deformity (VCD) is a common pathology in Chilean salmon farms, lowering the quality and commercialization of the product. Hypoxia has been related to other musculoskeletal deformities, but not to VCD. This work analyzes the morphology of the vertebral column of Salmo salar alevins, cultured under hypoxic conditions (60% O2 saturation in the water tanks) for different time periods after hatching (2, 4, 6 and 8 days). They are compared with their normoxic controls (100% O2 saturation). Using histological (H/E), and morphometric techniques, it was found that the time of exposure to hypoxia is inversely proportional to the body length, notochordal diameter and thickness of its sheath. The organic response to hypoxia was quantified by immunohistochemistry for HIF-1a as the sensor of hypoxia. Its expression increased significantly (p<0.05) in the experimental groups that exhibit VCD. Although etiology for VCD is probably multifactorial, this study allows for the conclusion t Article in Journal/Newspaper Salmo salar Universidad de Chile: Repositorio académico |
institution |
Open Polar |
collection |
Universidad de Chile: Repositorio académico |
op_collection_id |
ftunivchile |
language |
English |
topic |
Deformity Hypoxia Salmon Vertebral column |
spellingShingle |
Deformity Hypoxia Salmon Vertebral column Sánchez, Rodrigo Castro Obregón, Eduardo Bustos Rauco, Mariana Rojas Vertebral Column Deformity and hypoxia in Salmo salar Hipoxia relacionada a deformidad de columna vertebral en Salmo salar |
topic_facet |
Deformity Hypoxia Salmon Vertebral column |
description |
Vertebral Column Deformity (VCD) is a common pathology in Chilean salmon farms, lowering the quality and commercialization of the product. Hypoxia has been related to other musculoskeletal deformities, but not to VCD. This work analyzes the morphology of the vertebral column of Salmo salar alevins, cultured under hypoxic conditions (60% O2 saturation in the water tanks) for different time periods after hatching (2, 4, 6 and 8 days). They are compared with their normoxic controls (100% O2 saturation). Using histological (H/E), and morphometric techniques, it was found that the time of exposure to hypoxia is inversely proportional to the body length, notochordal diameter and thickness of its sheath. The organic response to hypoxia was quantified by immunohistochemistry for HIF-1a as the sensor of hypoxia. Its expression increased significantly (p<0.05) in the experimental groups that exhibit VCD. Although etiology for VCD is probably multifactorial, this study allows for the conclusion t |
format |
Article in Journal/Newspaper |
author |
Sánchez, Rodrigo Castro Obregón, Eduardo Bustos Rauco, Mariana Rojas |
author_facet |
Sánchez, Rodrigo Castro Obregón, Eduardo Bustos Rauco, Mariana Rojas |
author_sort |
Sánchez, Rodrigo Castro |
title |
Vertebral Column Deformity and hypoxia in Salmo salar Hipoxia relacionada a deformidad de columna vertebral en Salmo salar |
title_short |
Vertebral Column Deformity and hypoxia in Salmo salar Hipoxia relacionada a deformidad de columna vertebral en Salmo salar |
title_full |
Vertebral Column Deformity and hypoxia in Salmo salar Hipoxia relacionada a deformidad de columna vertebral en Salmo salar |
title_fullStr |
Vertebral Column Deformity and hypoxia in Salmo salar Hipoxia relacionada a deformidad de columna vertebral en Salmo salar |
title_full_unstemmed |
Vertebral Column Deformity and hypoxia in Salmo salar Hipoxia relacionada a deformidad de columna vertebral en Salmo salar |
title_sort |
vertebral column deformity and hypoxia in salmo salar hipoxia relacionada a deformidad de columna vertebral en salmo salar |
publishDate |
2011 |
url |
https://repositorio.uchile.cl/handle/2250/165503 |
genre |
Salmo salar |
genre_facet |
Salmo salar |
op_source |
International Journal of Morphology |
op_relation |
International Journal of Morphology, Volumen 29, Issue 4, 2018, Pages 1291-1295 07179367 07179502 https://repositorio.uchile.cl/handle/2250/165503 |
op_rights |
Attribution-NonCommercial-NoDerivs 3.0 Chile http://creativecommons.org/licenses/by-nc-nd/3.0/cl/ |
op_rightsnorm |
CC-BY-NC-ND |
_version_ |
1766182332764520448 |