HLA genes in Barranquilla (North Colombia): Searching for cryptic Amerindian genes

• Published in: Human Immunology
• Main Authors: Arnaiz Villena, Antonio, Bayona, Brayan, Palacio, Jose, Hernández Aguirre, Enio Armando, Muñiz, Ester, Campos, Cristina, Juarez, Ignacio, Gomez, Eduardo, Martín, Jose, Silvera, Carlos
• Format: Article in Journal/Newspaper
• Language: unknown
• Published: Universidad Cooperativa de Colombia, Facultad de Ciencias de la Salud, Medicina, Santa Marta 2018
• Subjects: Amerindian; Colombia; Barranquilla; Caucasoid; African; Cuba; eskimo*
• Online Access: https://hdl.handle.net/20.500.12494/4817

Investigación sobre las moléculas HLA, para caracterizar geneticamente la población de Barranquilla America First Inhabitants population (Amerindians, Na Dene and Eskimos) underwent a drastic population reduction and gene exchange after Europeans and Africans arrival after 1492 AD. Barranquilla population may be a good model to study present day population admixture in South America. HLA-A, -B and -DRB1 DNA typing has been performed in 188 unrelated individuals originated in the area and speak Spanish language; they showed apparent European/African and mixed characters. HLA genetic European/African features were found and only 1.85% Amerindian one. This contrasts with neighboring Cuban population where 10% HLA Amerindian characters appear. [e-mail] [e-mail]