Importancia clínica del distemper canino: una revisión

El VDC es causado por un Morbillivirus de la familia Paramyxoviridae similar al virus del sarampión humano, es una enfermedad grave y potencialmente mortal con distribución mundial. El agente causal del VDC puede llegar a infectar a caninos de todas las edades y razas, siendo más predisponentes los...

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Main Author: Beltrán Jimenéz, David Alejandro
Other Authors: Padilla Barreto, Mónica Yamile
Format: Thesis
Language:unknown
Published: Universidad Cooperativa de Colombia, Facultad de Ciencias de la Salud, Medicina Veterinaría y Zootecnia, Ibagué 2022
Subjects:
Virus del distemper canino (VDC)
Fiebre catarral infecciosa canina
Enfermedad viral
Inmunosupresión
TG 2022 MVZ 46450
Canine distemper virus (CDV)
Infectious canine catarrhal fever
Viral disease
Immunosuppression
Alta
Cachorros
Entrada
Fuerte
Sibirica
Online Access:https://repository.ucc.edu.co/handle/20.500.12494/46450
https://hdl.handle.net/20.500.12494/46450
id ftunivccolomb:oai:repository.ucc.edu.co:20.500.12494/46450
record_format openpolar
institution Open Polar
collection Repositorio Institucional UCC (Universidad Cooperativa de Colombia)
op_collection_id ftunivccolomb
language unknown
topic Virus del distemper canino (VDC)
Fiebre catarral infecciosa canina
Enfermedad viral
Inmunosupresión
TG 2022 MVZ 46450
Canine distemper virus (CDV)
Infectious canine catarrhal fever
Viral disease
Immunosuppression
spellingShingle Virus del distemper canino (VDC)
Fiebre catarral infecciosa canina
Enfermedad viral
Inmunosupresión
TG 2022 MVZ 46450
Canine distemper virus (CDV)
Infectious canine catarrhal fever
Viral disease
Immunosuppression
Beltrán Jimenéz, David Alejandro
Importancia clínica del distemper canino: una revisión
topic_facet Virus del distemper canino (VDC)
Fiebre catarral infecciosa canina
Enfermedad viral
Inmunosupresión
TG 2022 MVZ 46450
Canine distemper virus (CDV)
Infectious canine catarrhal fever
Viral disease
Immunosuppression
description El VDC es causado por un Morbillivirus de la familia Paramyxoviridae similar al virus del sarampión humano, es una enfermedad grave y potencialmente mortal con distribución mundial. El agente causal del VDC puede llegar a infectar a caninos de todas las edades y razas, siendo más predisponentes los cachorros; la diseminación se realiza a través de las secreciones biológicas, siendo la puerta de entrada el epitelio respiratorio superior, afectando principalmente a los linfocitos y macrófagos, generando como resultado una fuerte inmunosupresión. Los signos clínicos presentados son esencialmente en los sistemas respiratorio, gastrointestinal y nervioso central. El virus se transmite fácilmente entre huéspedes susceptibles y el canino sigue siendo el reservorio más importante de la infección, convirtiéndose en la enfermedad viral más conocida, temida y con la más alta prevalencia en caninos, causando más morbilidad y mortalidad que cualquier otro virus en caninos. CDV is caused by a Morbillivirus of the Paramyxoviridae family like to the human measles virus, it is a serious and deadly disease with worldwide distribution. The causal agent of CDV can infect canines of all ages and breeds, with puppies being more predisposed; the dissemination is carried out through biological secretions, the entrance door being the upper respiratory epithelium, hitting mainly the lymphocytes and macrophages, discovering as a result a strong immunosuppression. The clinical signs presented are frequent in the respiratory, gastrointestinal, and central nervous systems. The virus is easily transmitted between susceptible hosts and the canine remains the most important reservoir of infection, becoming the most well-known, feared and most prevalent viral disease in canines, causing more morbidity and mortality than any other virus in canines 1. Resumen. -- 2. Abstract. -- 3. Introducción. -- 4. Historia. -- 5. Etiología. -- 6. Epidemiologia. -- 7. Patogenia. -- 8. Signos clínicos. -- 9. Signos sistémicos. -- 10. Signos neurológicos. -- ...
author2 Padilla Barreto, Mónica Yamile
format Thesis
author Beltrán Jimenéz, David Alejandro
author_facet Beltrán Jimenéz, David Alejandro
author_sort Beltrán Jimenéz, David Alejandro
title Importancia clínica del distemper canino: una revisión
title_short Importancia clínica del distemper canino: una revisión
title_full Importancia clínica del distemper canino: una revisión
title_fullStr Importancia clínica del distemper canino: una revisión
title_full_unstemmed Importancia clínica del distemper canino: una revisión
title_sort importancia clínica del distemper canino: una revisión
publisher Universidad Cooperativa de Colombia, Facultad de Ciencias de la Salud, Medicina Veterinaría y Zootecnia, Ibagué
publishDate 2022
url https://repository.ucc.edu.co/handle/20.500.12494/46450
https://hdl.handle.net/20.500.12494/46450
long_lat ENVELOPE(-60.783,-60.783,-62.450,-62.450)
ENVELOPE(-60.552,-60.552,-62.998,-62.998)
ENVELOPE(-54.083,-54.083,-61.200,-61.200)
geographic Alta
Cachorros
Entrada
Fuerte
geographic_facet Alta
Cachorros
Entrada
Fuerte
genre Sibirica
genre_facet Sibirica
op_relation Guerrero Castro MC. Principales enfermedades Infecciosas de los mamíferos domésticos. Primera. del Tolima Universidad, editor. Bogota : 2009; 2009. 1–311 p.
Céspedes PF, Cruz P, Navarro CO. Modulación de la respuesta inmune durante la infección por virus distemper canino: implicancias terapéuticas y en el desarrollo de vacunas Modulation of immune response during canine distemper virus infection : therapeutic and vaccine development implica. Arch Med Vet [Internet]. 2010; 42:15–28. Available from: https://scielo.conicyt.cl/pdf/amv/v42n2/art03.pdf
Prager KC, Mazet JAK, Dubovi EJ, Frank LG, Munson L, Wagner AP, et al. Rabies virus and canine distemper virus in wild and domestic carnivores in Northern Kenya: Are domestic dogs the reservoir? Ecohealth. 2012;9(4).
Woma TY, van Vuuren M, Bosman AM, Quan M, Oosthuizen M. Phylogenetic analysis of the haemagglutinin gene of current wild-type canine distemper viruses from South Africa: Lineage Africa. Vet Microbiol. 2010;143(2–4).
Viana M, Cleaveland S, Matthiopoulos J, Halliday J, Packer C, Craft ME, et al. Dynamics of a morbillivirus at the domestic -wildlife interface: Canine distemper virus in domestic dogs and lions. Proc Natl Acad Sci U S A. 2015;112(5).
Davidson-Phillips S, Davidson-Phillips P, Canning G, Schroder B, Swart J, Burger A. Canine Distemper Virus Management in Lions (Panthera leo) on Welgevonden Game Reserve. Afr J Wildl Res. 2019;49(1).
Butina T v., Denikina NN, Belikov SI. Canine distemper virus diversity in Lake Baikal seal (Phoca sibirica) population. Vet Microbiol. 2010;144(1–2).
Bauer KL, Goertz CEC, Belovarac JA, Walton RW, Lawrence Dunn J, Tuomi P. Infectious disease and toxicological monitoring of stranded pacific harbor seals (Phoca vitulina richardsi) in cook inlet as surrogates for monitoring endangered belugas (Delphinapterus leucas). Journal of Zoo and Wildlife Medicine. 2016;47(3).
Stokholm I, Puryear W, Sawatzki K, Knudsen SW, Terkelsen T, Becher P, et al. Emergence and radiation of distemper viruses in terrestrial and marine mammals. Proceedings of the Royal Society B: Biological Sciences. 2021;288(1961).
Pinotti MA. Distemper Canino: Evaluación De Dos Alternativas Terapéuticas Y Caracterización De Aspectos Clínico-Epidemiológico En La Ciudad De Santa Fe. Universidad Nacional del Litorial. 2011;1–114.
Rohowsky-Kochan C, Davidow A, Dowling P, Cook SD. Increased frequency of canine distemper virus-specific antibodies in multiple sclerosis. Brain Behav. 2021;11(1):1–9.
The Center for Food Security and Public Health. Peste De Los Pequeños Rumiantes (Ppr). Iowa State University. 2010;(17).
Quintero-Gil C, Rendon-Marin S, Martinez-Gutierrez M, Ruiz-Saenz J. Origin of canine distemper virus: Consolidating evidence to understand potential zoonoses. Front Microbiol. 2019;10(AUG):1–5.
Soto AR, Luna LRE, Rosadio RA, Maturrano LH. Molecular detection of canine distemper virus in clinical cases from unvaccinated domestic dogs and assessment of risk factors. Revista de Investigaciones Veterinarias del Peru. 2018;29(3):964–71.
de Vries RD, Paul Duprex W, de Swart RL. Morbillivirus infections: An introduction. Viruses. 2015;7(2):699–706.
Hospital XR, Molins V, Feliz G. Actualización en el diagnóstico del moquillo canino neurológico. 2018 Dec 24 [cited 2022 Aug 23]; Available from: https://www.researchgate.net/publication/329894324
Lempp C, Spitzbarth I, Puff C, Cana A, Kegler K, Techangamsuwan S, et al. New aspects of the pathogenesis of canine distemper leukoencephalitis. Viruses. 2014;6(7).
Loots AK, Mitchell E, Dalton DL, Kotzé A, Venter EH. Advances in canine distemper virus pathogenesis research: A wildlife perspective. Journal of General Virology. 2017;98(3):311–21.
Garde E, Pérez G, Acosta-Jamett G, Bronsvoort BM. Characteristics of a canine distemper virus outbreak in Dichato, Chile following the February 2010 earthquake. Animals. 2013;3(3):843–54.
Sanekata T, Fukuda T, Miura T, Morino H, Lee C, Maeda K, et al. Evaluation of the antiviral activity of chlorine dioxide and sodium hypochlorite against feline calicivirus, human influenza virus, measles virus, canine distemper virus, human herpesvirus, human adenovirus, canine adenovirus and canine parvovirus. Vol. 15, Biocontrol Science. 2010. p. 45–9.
Canales K´ana DH. Virus del distemper canino: Revisión actualizada del agente y la patogenia de la enfermedad. 2020;46. Available from: https://cybertesis.unmsm.edu.pe/bitstream/handle/20.500.12672/12267/Canales_kd.pdf?sequence=1&isAllowed=y
Codina MG, de Cueto M, Vicente D, Echevarría JE, Prats G. Microbiological diagnosis of central nervous system infections. Enferm Infecc Microbiol Clin. 2011;29(2):127–34.
Zachary JF. Pathologic Basis of Veterinary Disease. Pathologic Basis of Veterinary Disease. 2017.
Headley SA, Shirota K, Baba T, Ikeda T, Sukura A. Diagnostic exercise: Tyzzer’s disease, distemper, and coccidiosis in a pup. Vet Pathol. 2010;46(1):151–4.
Åkerstedt J, Lillehaug A, Larsen IL, Eide NE, Arnemo JM, Handeland K. Serosurvey for canine distemper virus, canine adenovirus, leptospira interrogans, andtoxoplasma gondii in free-ranging canids in Scandinavia And Svalbard. J Wildl Dis. 2010;46(2):474–80.
Beineke A, Baumgärtner W, Wohlsein P. Cross-species transmission of canine distemper virus-an update. One Health [Internet]. 2015; 1:49–59. Available from: http://dx.doi.org/10.1016/j.onehlt.2015.09.002
Megid J, Teixeira CR, Cortez A, Heinemann MB, Antunes JMAP, Fornazari F, et al. Canine distemper virus infection in a lesser grison (Galictis cuja): First report and virus phylogeny. Pesquisa Veterinaria Brasileira. 2013;33(2):247–50.
Zhao N, Li M, Luo J, Wang S, Liu S, Wang S, et al. Impacts of canine distemper virus infection on the giant panda population from the perspective of gut microbiota. Sci Rep [Internet]. 2017;7(November 2016):1–10. Available from: http://dx.doi.org/10.1038/srep39954
Bunting B. Canine Distemper and Raccoons. 2019;15–8. Available from: https://cwhl.vet.cornell.edu/article/canine-distemper-and-raccoons
Debesa Belizário Granjeiro M, Lima Kavasaki M, Morgado TO, Avelino Dandolini Pavelegini L, Alves de Barros M, Fontana C, et al. First report of a canine morbillivirus infection in a giant anteater (Myrmecophaga tridactyla) in Brazil. Vet Med Sci. 2020;6(3):606–11.
Michelazzo M de MZ, de Oliveira TES, Viana NE, de Moraes W, Cubas ZS, Headley SA. Immunohistochemical evidence of canine morbillivirus (canine distemper) infection in coatis (Nasua nasua) from Southern Brazil. Transbound Emerg Dis. 2020;67(S2):178–84.
Jubb K& P. Pathology of domestic animals: Sixth edition. Vol. 1, Jubb, Kennedy & Palmer’s Pathology of Domestic Animals: Sixth Edition. 2015. 1–798 p.
Abdullah N, Kelly JT, Graham SC, Birch J, Gonçalves-Carneiro D, Mitchell T, et al. Structure-Guided Identification of a Nonhuman Morbillivirus with Zoonotic Potential. J Virol. 2018;92(23).
Schumaker BA, Miller MM, Grosdidier P, Cavender JL, Montgomery DL, Cornish TE, et al. Canine distemper outbreak in pet store puppies linked to a high-volume dog breeder. Journal of Veterinary Diagnostic Investigation. 2012;24(6):1094–8.
Vila Nova B, Cunha E, Sepúlveda N, Oliveira M, São Braz B, Tavares L, et al. Evaluation of the humoral immune response induced by vaccination for canine distemper and parvovirus: A pilot study. BMC Vet Res. 2018;14(1):1–8.
Cunha RDS, da Silva Junior CL, Costa CA, de Aguiar HM, Junqueira Júnior DG. Comparison of immunity against canine distemper, adenovirus and parvovirus after vaccination with two multivalent canine vaccines. Vet Med Sci. 2020;6(3):330–4.
Headley SA, Oliveira TES, Pereira AHT, Moreira JR, Michelazzo MMZ, Pires BG, et al. Canine morbillivirus (canine distemper virus) with concomitant canine adenovirus, canine parvovirus-2, and Neospora caninum in puppies: a retrospective immunohistochemical study. Sci Rep. 2018;8(1):1–16.
Amude AM, Alfieri AA, Arias MVB, Alfieri AF. Clinical syndromes of nervous distemper in dogs initially presented without conventional evidences of CDV infection. Semina:Ciencias Agrarias. 2012;33(6):2347–57.
Awad R. Rapid Approaches for Diagnosis of Canine Distemper Virus in Live and Dead Dogs in Egypt. Egyptian Journal of Veterinary Sciences. 2019;50(1):47–56.
Taques IIGG, Morgado TO, Braga ÍA, Paz RCR, Corrêa SHR, Fritzen JTT, et al. Antibodies against canine distemper virus, parvovirus and Ehrlichia spp. in wild captive carnivores in midwestern Brazil. Pesquisa Veterinaria Brasileira. 2018;38(8):1681–4.
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op_rights Atribución – No comercial – Compartir igual
openAccess
op_doi https://doi.org/20.500.12494/4645010.1016/j.onehlt.2015.09.00210.1038/srep3995410.22192/ijarbs.2021.08.06.001
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spelling ftunivccolomb:oai:repository.ucc.edu.co:20.500.12494/46450 2024-02-11T10:08:34+01:00 Importancia clínica del distemper canino: una revisión Beltrán Jimenéz, David Alejandro Padilla Barreto, Mónica Yamile 2022-09-09 29 p. application/pdf https://repository.ucc.edu.co/handle/20.500.12494/46450 https://hdl.handle.net/20.500.12494/46450 unknown Universidad Cooperativa de Colombia, Facultad de Ciencias de la Salud, Medicina Veterinaría y Zootecnia, Ibagué Ibagué Medicina veterinaria y zootecnia Guerrero Castro MC. Principales enfermedades Infecciosas de los mamíferos domésticos. Primera. del Tolima Universidad, editor. Bogota : 2009; 2009. 1–311 p. Céspedes PF, Cruz P, Navarro CO. Modulación de la respuesta inmune durante la infección por virus distemper canino: implicancias terapéuticas y en el desarrollo de vacunas Modulation of immune response during canine distemper virus infection : therapeutic and vaccine development implica. Arch Med Vet [Internet]. 2010; 42:15–28. Available from: https://scielo.conicyt.cl/pdf/amv/v42n2/art03.pdf Prager KC, Mazet JAK, Dubovi EJ, Frank LG, Munson L, Wagner AP, et al. Rabies virus and canine distemper virus in wild and domestic carnivores in Northern Kenya: Are domestic dogs the reservoir? Ecohealth. 2012;9(4). Woma TY, van Vuuren M, Bosman AM, Quan M, Oosthuizen M. Phylogenetic analysis of the haemagglutinin gene of current wild-type canine distemper viruses from South Africa: Lineage Africa. Vet Microbiol. 2010;143(2–4). Viana M, Cleaveland S, Matthiopoulos J, Halliday J, Packer C, Craft ME, et al. Dynamics of a morbillivirus at the domestic -wildlife interface: Canine distemper virus in domestic dogs and lions. Proc Natl Acad Sci U S A. 2015;112(5). Davidson-Phillips S, Davidson-Phillips P, Canning G, Schroder B, Swart J, Burger A. Canine Distemper Virus Management in Lions (Panthera leo) on Welgevonden Game Reserve. Afr J Wildl Res. 2019;49(1). Butina T v., Denikina NN, Belikov SI. Canine distemper virus diversity in Lake Baikal seal (Phoca sibirica) population. Vet Microbiol. 2010;144(1–2). Bauer KL, Goertz CEC, Belovarac JA, Walton RW, Lawrence Dunn J, Tuomi P. Infectious disease and toxicological monitoring of stranded pacific harbor seals (Phoca vitulina richardsi) in cook inlet as surrogates for monitoring endangered belugas (Delphinapterus leucas). Journal of Zoo and Wildlife Medicine. 2016;47(3). Stokholm I, Puryear W, Sawatzki K, Knudsen SW, Terkelsen T, Becher P, et al. Emergence and radiation of distemper viruses in terrestrial and marine mammals. Proceedings of the Royal Society B: Biological Sciences. 2021;288(1961). Pinotti MA. Distemper Canino: Evaluación De Dos Alternativas Terapéuticas Y Caracterización De Aspectos Clínico-Epidemiológico En La Ciudad De Santa Fe. Universidad Nacional del Litorial. 2011;1–114. Rohowsky-Kochan C, Davidow A, Dowling P, Cook SD. Increased frequency of canine distemper virus-specific antibodies in multiple sclerosis. Brain Behav. 2021;11(1):1–9. The Center for Food Security and Public Health. Peste De Los Pequeños Rumiantes (Ppr). Iowa State University. 2010;(17). Quintero-Gil C, Rendon-Marin S, Martinez-Gutierrez M, Ruiz-Saenz J. Origin of canine distemper virus: Consolidating evidence to understand potential zoonoses. Front Microbiol. 2019;10(AUG):1–5. Soto AR, Luna LRE, Rosadio RA, Maturrano LH. Molecular detection of canine distemper virus in clinical cases from unvaccinated domestic dogs and assessment of risk factors. Revista de Investigaciones Veterinarias del Peru. 2018;29(3):964–71. de Vries RD, Paul Duprex W, de Swart RL. Morbillivirus infections: An introduction. Viruses. 2015;7(2):699–706. Hospital XR, Molins V, Feliz G. Actualización en el diagnóstico del moquillo canino neurológico. 2018 Dec 24 [cited 2022 Aug 23]; Available from: https://www.researchgate.net/publication/329894324 Lempp C, Spitzbarth I, Puff C, Cana A, Kegler K, Techangamsuwan S, et al. New aspects of the pathogenesis of canine distemper leukoencephalitis. Viruses. 2014;6(7). Loots AK, Mitchell E, Dalton DL, Kotzé A, Venter EH. Advances in canine distemper virus pathogenesis research: A wildlife perspective. Journal of General Virology. 2017;98(3):311–21. Garde E, Pérez G, Acosta-Jamett G, Bronsvoort BM. Characteristics of a canine distemper virus outbreak in Dichato, Chile following the February 2010 earthquake. Animals. 2013;3(3):843–54. Sanekata T, Fukuda T, Miura T, Morino H, Lee C, Maeda K, et al. Evaluation of the antiviral activity of chlorine dioxide and sodium hypochlorite against feline calicivirus, human influenza virus, measles virus, canine distemper virus, human herpesvirus, human adenovirus, canine adenovirus and canine parvovirus. Vol. 15, Biocontrol Science. 2010. p. 45–9. Canales K´ana DH. Virus del distemper canino: Revisión actualizada del agente y la patogenia de la enfermedad. 2020;46. Available from: https://cybertesis.unmsm.edu.pe/bitstream/handle/20.500.12672/12267/Canales_kd.pdf?sequence=1&isAllowed=y Codina MG, de Cueto M, Vicente D, Echevarría JE, Prats G. Microbiological diagnosis of central nervous system infections. Enferm Infecc Microbiol Clin. 2011;29(2):127–34. Zachary JF. Pathologic Basis of Veterinary Disease. Pathologic Basis of Veterinary Disease. 2017. Headley SA, Shirota K, Baba T, Ikeda T, Sukura A. Diagnostic exercise: Tyzzer’s disease, distemper, and coccidiosis in a pup. Vet Pathol. 2010;46(1):151–4. Åkerstedt J, Lillehaug A, Larsen IL, Eide NE, Arnemo JM, Handeland K. Serosurvey for canine distemper virus, canine adenovirus, leptospira interrogans, andtoxoplasma gondii in free-ranging canids in Scandinavia And Svalbard. J Wildl Dis. 2010;46(2):474–80. Beineke A, Baumgärtner W, Wohlsein P. Cross-species transmission of canine distemper virus-an update. One Health [Internet]. 2015; 1:49–59. Available from: http://dx.doi.org/10.1016/j.onehlt.2015.09.002 Megid J, Teixeira CR, Cortez A, Heinemann MB, Antunes JMAP, Fornazari F, et al. Canine distemper virus infection in a lesser grison (Galictis cuja): First report and virus phylogeny. Pesquisa Veterinaria Brasileira. 2013;33(2):247–50. Zhao N, Li M, Luo J, Wang S, Liu S, Wang S, et al. Impacts of canine distemper virus infection on the giant panda population from the perspective of gut microbiota. Sci Rep [Internet]. 2017;7(November 2016):1–10. Available from: http://dx.doi.org/10.1038/srep39954 Bunting B. Canine Distemper and Raccoons. 2019;15–8. Available from: https://cwhl.vet.cornell.edu/article/canine-distemper-and-raccoons Debesa Belizário Granjeiro M, Lima Kavasaki M, Morgado TO, Avelino Dandolini Pavelegini L, Alves de Barros M, Fontana C, et al. First report of a canine morbillivirus infection in a giant anteater (Myrmecophaga tridactyla) in Brazil. Vet Med Sci. 2020;6(3):606–11. Michelazzo M de MZ, de Oliveira TES, Viana NE, de Moraes W, Cubas ZS, Headley SA. Immunohistochemical evidence of canine morbillivirus (canine distemper) infection in coatis (Nasua nasua) from Southern Brazil. Transbound Emerg Dis. 2020;67(S2):178–84. Jubb K& P. Pathology of domestic animals: Sixth edition. Vol. 1, Jubb, Kennedy & Palmer’s Pathology of Domestic Animals: Sixth Edition. 2015. 1–798 p. Abdullah N, Kelly JT, Graham SC, Birch J, Gonçalves-Carneiro D, Mitchell T, et al. Structure-Guided Identification of a Nonhuman Morbillivirus with Zoonotic Potential. J Virol. 2018;92(23). Schumaker BA, Miller MM, Grosdidier P, Cavender JL, Montgomery DL, Cornish TE, et al. Canine distemper outbreak in pet store puppies linked to a high-volume dog breeder. Journal of Veterinary Diagnostic Investigation. 2012;24(6):1094–8. Vila Nova B, Cunha E, Sepúlveda N, Oliveira M, São Braz B, Tavares L, et al. Evaluation of the humoral immune response induced by vaccination for canine distemper and parvovirus: A pilot study. BMC Vet Res. 2018;14(1):1–8. Cunha RDS, da Silva Junior CL, Costa CA, de Aguiar HM, Junqueira Júnior DG. Comparison of immunity against canine distemper, adenovirus and parvovirus after vaccination with two multivalent canine vaccines. Vet Med Sci. 2020;6(3):330–4. Headley SA, Oliveira TES, Pereira AHT, Moreira JR, Michelazzo MMZ, Pires BG, et al. Canine morbillivirus (canine distemper virus) with concomitant canine adenovirus, canine parvovirus-2, and Neospora caninum in puppies: a retrospective immunohistochemical study. Sci Rep. 2018;8(1):1–16. Amude AM, Alfieri AA, Arias MVB, Alfieri AF. Clinical syndromes of nervous distemper in dogs initially presented without conventional evidences of CDV infection. Semina:Ciencias Agrarias. 2012;33(6):2347–57. Awad R. Rapid Approaches for Diagnosis of Canine Distemper Virus in Live and Dead Dogs in Egypt. 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The nervous form of canine distemper. Veterinária e Zootecnia. 2018;13(2):125–36. Maboni G, Seguel M, Lorton A, Berghaus R, Sanchez S. Canine infectious respiratory disease: New insights into the etiology and epidemiology of associated pathogens. PLoS One. 2019;14(4). Atribución – No comercial – Compartir igual openAccess Virus del distemper canino (VDC) Fiebre catarral infecciosa canina Enfermedad viral Inmunosupresión TG 2022 MVZ 46450 Canine distemper virus (CDV) Infectious canine catarrhal fever Viral disease Immunosuppression Trabajos de grado - Pregrado 2022 ftunivccolomb https://doi.org/20.500.12494/4645010.1016/j.onehlt.2015.09.00210.1038/srep3995410.22192/ijarbs.2021.08.06.001 2024-01-21T19:11:56Z El VDC es causado por un Morbillivirus de la familia Paramyxoviridae similar al virus del sarampión humano, es una enfermedad grave y potencialmente mortal con distribución mundial. El agente causal del VDC puede llegar a infectar a caninos de todas las edades y razas, siendo más predisponentes los cachorros; la diseminación se realiza a través de las secreciones biológicas, siendo la puerta de entrada el epitelio respiratorio superior, afectando principalmente a los linfocitos y macrófagos, generando como resultado una fuerte inmunosupresión. Los signos clínicos presentados son esencialmente en los sistemas respiratorio, gastrointestinal y nervioso central. El virus se transmite fácilmente entre huéspedes susceptibles y el canino sigue siendo el reservorio más importante de la infección, convirtiéndose en la enfermedad viral más conocida, temida y con la más alta prevalencia en caninos, causando más morbilidad y mortalidad que cualquier otro virus en caninos. CDV is caused by a Morbillivirus of the Paramyxoviridae family like to the human measles virus, it is a serious and deadly disease with worldwide distribution. The causal agent of CDV can infect canines of all ages and breeds, with puppies being more predisposed; the dissemination is carried out through biological secretions, the entrance door being the upper respiratory epithelium, hitting mainly the lymphocytes and macrophages, discovering as a result a strong immunosuppression. The clinical signs presented are frequent in the respiratory, gastrointestinal, and central nervous systems. The virus is easily transmitted between susceptible hosts and the canine remains the most important reservoir of infection, becoming the most well-known, feared and most prevalent viral disease in canines, causing more morbidity and mortality than any other virus in canines 1. Resumen. -- 2. Abstract. -- 3. Introducción. -- 4. Historia. -- 5. Etiología. -- 6. Epidemiologia. -- 7. Patogenia. -- 8. Signos clínicos. -- 9. Signos sistémicos. -- 10. Signos neurológicos. -- ... Thesis Sibirica Repositorio Institucional UCC (Universidad Cooperativa de Colombia) Alta Cachorros ENVELOPE(-60.783,-60.783,-62.450,-62.450) Entrada ENVELOPE(-60.552,-60.552,-62.998,-62.998) Fuerte ENVELOPE(-54.083,-54.083,-61.200,-61.200)

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