HLA genes in Barranquilla (North Colombia): Searching for cryptic Amerindian genes

• Published in: Journal of Molecular Liquids
• Main Authors: Arnaiz-Villena A., Bayona B., Palacio-Gruber J., Hernandez Aguirre, Enio Armando, Muñiz E., Campos C., Juarez I., Gomez-Casado E., Martín-Villa J.M., Silvera C.
• Format: Article in Journal/Newspaper
• Language: unknown
• Published: Elsevier Inc. 2017
• Subjects: African; Amerindian; Barranquilla; Caucasoid; Colombia; Cuba; HLA; eskimo*
• Online Access: https://hdl.handle.net/20.500.12494/41466; https://doi.org/10.1016/j.molliq.2014.06.006

America First Inhabitants population (Amerindians, Na Dene and Eskimos) underwent a drastic population reduction and gene exchange after Europeans and Africans arrival after 1492 AD. Barranquilla population may be a good model to study present day population admixture in South America. HLA-A, -B and -DRB1 DNA typing has been performed in 188 unrelated individuals originated in the area and speak Spanish language; they showed apparent European/African and mixed characters. HLA genetic European/African features were found and only 1.85% Amerindian one. This contrasts with neighboring Cuban population where 10% HLA Amerindian characters appear. © 2017.