Cloning and unusual expression profile of the aldolase B gene from Atlantic salmon

A full-length clone of the aldolase B gene has been isolated from a cDNA library constructed from liver of Atlantic salmon (Salmo salar). Sequencing showed that the clone encodes a typical aldolase B, possessing a number of amino acid residues which are seen in aldolase B, but not in other aldolase...

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Bibliographic Details
Published in:Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression
Main Authors: Llewellyn, Lynda, Sweeney, Glen E., Ramsurn, Vimi P., Rogers, Sarah A., Wigham, Trevor
Format: Article in Journal/Newspaper
Language:unknown
Published: Elsevier 1998
Subjects:
Atlantic salmon
Salmo salar
Online Access:https://orca.cardiff.ac.uk/id/eprint/65593/
https://doi.org/10.1016/S0167-4781(98)00229-2
Description
Summary:A full-length clone of the aldolase B gene has been isolated from a cDNA library constructed from liver of Atlantic salmon (Salmo salar). Sequencing showed that the clone encodes a typical aldolase B, possessing a number of amino acid residues which are seen in aldolase B, but not in other aldolase isoforms. RT-PCR analysis showed that the gene is expressed in liver, kidney and intestine as expected. However, in contrast to mammalian and avian aldolase B, expression was also found in a number of other tissues. Levels of aldolase B mRNA in liver and kidney were not significantly altered during smoltification, the transformation of freshwater-dwelling salmon (parr) into saltwater-adapted salmon (smolts).

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