Fish polyomaviruses belong to two distinct evolutionary lineages.

The Polyomaviridae is a diverse family of circular double-stranded DNA viruses. Polyomaviruses have been isolated from a wide array of animal hosts. An understanding of the evolutionary and ecological dynamics of these viruses is essential to understanding the pathogenicity of polyomaviruses. Using...

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Bibliographic Details
Published in:Journal of General Virology
Main Authors: Van Doorslaer K, Kraberger S, Austin C, Farkas K, Bergeman M, Paunil E, Davison W, Varsani A
Format: Article in Journal/Newspaper
Language:English
Published: 2018
Subjects:
Polyomaviridae
Antarctica
emerald notothen
Trematomus bernacchii
Fields of Research::31 - Biological sciences::3107 - Microbiology::310706 - Virology
Fields of Research::31 - Biological sciences::3104 - Evolutionary biology::310410 - Phylogeny and comparative analysis
Ross Sea
Antarc*
Online Access:http://hdl.handle.net/10092/16229
https://doi.org/10.1099/jgv.0.001041
Description
Summary:The Polyomaviridae is a diverse family of circular double-stranded DNA viruses. Polyomaviruses have been isolated from a wide array of animal hosts. An understanding of the evolutionary and ecological dynamics of these viruses is essential to understanding the pathogenicity of polyomaviruses. Using a high throughput sequencing approach, we identified a novel polyomavirus in an emerald notothen (Trematomus bernacchii) sampled in the Ross sea (Antarctica), expanding the known number of fish-associated polyomaviruses. Our analysis suggests that polyomaviruses belong to three main evolutionary clades; the first clade is made up of all recognized terrestrial polyomaviruses. The fish-associated polyomaviruses are not monophyletic, and belong to two divergent evolutionary lineages. The fish viruses provide evidence that the evolution of the key viral large T protein involves gain and loss of distinct domains.

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