Evolutionary conservation and divergence of the transcriptional regulation of bivalve shell secretion across life-history stages.
Peer reviewed: True Adult molluscs produce shells with diverse morphologies and ornamentations, different colour patterns and microstructures. The larval shell, however, is a phenotypically more conserved structure. How do developmental and evolutionary processes generate varying diversity at differ...
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ftunivcam:oai:www.repository.cam.ac.uk:1810/348709 2024-02-04T09:54:28+01:00 Evolutionary conservation and divergence of the transcriptional regulation of bivalve shell secretion across life-history stages. Cavallo, Alessandro Clark, Melody S Peck, Lloyd S Harper, Elizabeth M Sleight, Victoria A 2023-04-17T12:00:41Z application/pdf text/xml https://www.repository.cam.ac.uk/handle/1810/348709 https://doi.org/10.17863/CAM.96135 en eng eng The Royal Society http://dx.doi.org/10.1098/rsos.221022 R Soc Open Sci https://www.repository.cam.ac.uk/handle/1810/348709 doi:10.17863/CAM.96135 biomineralization evo devo mollusc shell development Article 2023 ftunivcam https://doi.org/10.17863/CAM.96135 2024-01-11T23:21:07Z Peer reviewed: True Adult molluscs produce shells with diverse morphologies and ornamentations, different colour patterns and microstructures. The larval shell, however, is a phenotypically more conserved structure. How do developmental and evolutionary processes generate varying diversity at different life-history stages within a species? Using live imaging, histology, scanning electron microscopy and transcriptomic profiling, we have described shell development in a heteroconchian bivalve, the Antarctic clam, Laternula elliptica, and compared it to adult shell secretion processes in the same species. Adult downstream shell genes, such as those encoding extracellular matrix proteins and biomineralization enzymes, were largely not expressed during shell development. Instead, a development-specific downstream gene repertoire was expressed. Upstream regulatory genes such as transcription factors and signalling molecules were largely conserved between developmental and adult shell secretion. Comparing heteroconchian data with recently reported pteriomorphian larval shell development data suggests that, despite being phenotypically more conserved, the downstream effectors constituting the larval shell 'tool-kit' may be as diverse as that of adults. Overall, our new data suggest that a larval shell formed using development-specific downstream effector genes is a conserved and ancestral feature of the bivalve lineage, and possibly more broadly across the molluscs. Article in Journal/Newspaper Antarc* Antarctic Apollo - University of Cambridge Repository Antarctic The Antarctic |
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Apollo - University of Cambridge Repository |
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language |
English |
topic |
biomineralization evo devo mollusc shell development |
spellingShingle |
biomineralization evo devo mollusc shell development Cavallo, Alessandro Clark, Melody S Peck, Lloyd S Harper, Elizabeth M Sleight, Victoria A Evolutionary conservation and divergence of the transcriptional regulation of bivalve shell secretion across life-history stages. |
topic_facet |
biomineralization evo devo mollusc shell development |
description |
Peer reviewed: True Adult molluscs produce shells with diverse morphologies and ornamentations, different colour patterns and microstructures. The larval shell, however, is a phenotypically more conserved structure. How do developmental and evolutionary processes generate varying diversity at different life-history stages within a species? Using live imaging, histology, scanning electron microscopy and transcriptomic profiling, we have described shell development in a heteroconchian bivalve, the Antarctic clam, Laternula elliptica, and compared it to adult shell secretion processes in the same species. Adult downstream shell genes, such as those encoding extracellular matrix proteins and biomineralization enzymes, were largely not expressed during shell development. Instead, a development-specific downstream gene repertoire was expressed. Upstream regulatory genes such as transcription factors and signalling molecules were largely conserved between developmental and adult shell secretion. Comparing heteroconchian data with recently reported pteriomorphian larval shell development data suggests that, despite being phenotypically more conserved, the downstream effectors constituting the larval shell 'tool-kit' may be as diverse as that of adults. Overall, our new data suggest that a larval shell formed using development-specific downstream effector genes is a conserved and ancestral feature of the bivalve lineage, and possibly more broadly across the molluscs. |
format |
Article in Journal/Newspaper |
author |
Cavallo, Alessandro Clark, Melody S Peck, Lloyd S Harper, Elizabeth M Sleight, Victoria A |
author_facet |
Cavallo, Alessandro Clark, Melody S Peck, Lloyd S Harper, Elizabeth M Sleight, Victoria A |
author_sort |
Cavallo, Alessandro |
title |
Evolutionary conservation and divergence of the transcriptional regulation of bivalve shell secretion across life-history stages. |
title_short |
Evolutionary conservation and divergence of the transcriptional regulation of bivalve shell secretion across life-history stages. |
title_full |
Evolutionary conservation and divergence of the transcriptional regulation of bivalve shell secretion across life-history stages. |
title_fullStr |
Evolutionary conservation and divergence of the transcriptional regulation of bivalve shell secretion across life-history stages. |
title_full_unstemmed |
Evolutionary conservation and divergence of the transcriptional regulation of bivalve shell secretion across life-history stages. |
title_sort |
evolutionary conservation and divergence of the transcriptional regulation of bivalve shell secretion across life-history stages. |
publisher |
The Royal Society |
publishDate |
2023 |
url |
https://www.repository.cam.ac.uk/handle/1810/348709 https://doi.org/10.17863/CAM.96135 |
geographic |
Antarctic The Antarctic |
geographic_facet |
Antarctic The Antarctic |
genre |
Antarc* Antarctic |
genre_facet |
Antarc* Antarctic |
op_relation |
https://www.repository.cam.ac.uk/handle/1810/348709 doi:10.17863/CAM.96135 |
op_doi |
https://doi.org/10.17863/CAM.96135 |
_version_ |
1789974159368912896 |