Comprehensive annotation and evolutionary insights into the canine (Canis lupus familiaris) antigen receptor loci

• Main Authors: Martin, JNE, Ponstingl, H, Lefranc, M, Archer, J, Sargan, D, Bradley, A
• Format: Article in Journal/Newspaper
• Language: English
• Published: Springer Nature 2018
• Subjects: Canine; Antigen receptor; Immunoglobulin; T cell receptor; Lambda; Canis lupus
• Online Access: https://www.repository.cam.ac.uk/handle/1810/267510; https://doi.org/10.17863/CAM.13449

Dogs are an excellent model for human disease. For example, the treatment of canine lymphoma has been predictive of the human response to that treatment. However, an incomplete picture of canine (Canis lupus familiaris) immunoglobulin (IG) and T cell receptor (TR) - or antigen receptor (AR) - gene l...