Host-microbiota interactions shed light on mortality events in the striped venus clam Chamelea gallina
WOS:000487521600001 International audience Mass mortalities due to disease outbreaks have recently affected a number of major taxa in marine ecosystems. Climate- and pollution-induced stress may compromise host immune defenses, increasing the risk of opportunistic diseases. Despite growing evidence...
Published in: | Molecular Ecology |
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Main Authors: | , , , , , , , , , , , , , , , , , , |
Other Authors: | , , , , , , , , |
Format: | Article in Journal/Newspaper |
Language: | English |
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HAL CCSD
2019
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Subjects: | |
Online Access: | https://hal.science/hal-02873898 https://doi.org/10.1111/mec.15227 |
id |
ftunivbrest:oai:HAL:hal-02873898v1 |
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record_format |
openpolar |
institution |
Open Polar |
collection |
Université de Bretagne Occidentale: HAL |
op_collection_id |
ftunivbrest |
language |
English |
topic |
ACL oncorhynchus-mykiss rainbow-trout bivalve crassostrea-gigas pacific oysters mass mortality transcriptomics vibrio-splendidus adriatic sea damselae subsp damselae haliotis-diversicolor-supertexta host-microbiota interactions immune-response molluscs pollutant-pathogen interactions ssp damselae [SDE.BE]Environmental Sciences/Biodiversity and Ecology |
spellingShingle |
ACL oncorhynchus-mykiss rainbow-trout bivalve crassostrea-gigas pacific oysters mass mortality transcriptomics vibrio-splendidus adriatic sea damselae subsp damselae haliotis-diversicolor-supertexta host-microbiota interactions immune-response molluscs pollutant-pathogen interactions ssp damselae [SDE.BE]Environmental Sciences/Biodiversity and Ecology Milan, Massimo Smits, Morgan Dalla Rovere, Giulia Iori, Silvia Zampieri, Angela Carraro, Lisa Martino, Camillo Papetti, Chiara Ianni, Andrea Ferri, Nicola Iannaccone, Marco Patarnello, Tomaso Brunetta, Romina Ciofi, Claudio Grotta, Lisa Arcangeli, Giuseppe Bargelloni, Luca Cardazzo, Barbara Martino, Giuseppe Host-microbiota interactions shed light on mortality events in the striped venus clam Chamelea gallina |
topic_facet |
ACL oncorhynchus-mykiss rainbow-trout bivalve crassostrea-gigas pacific oysters mass mortality transcriptomics vibrio-splendidus adriatic sea damselae subsp damselae haliotis-diversicolor-supertexta host-microbiota interactions immune-response molluscs pollutant-pathogen interactions ssp damselae [SDE.BE]Environmental Sciences/Biodiversity and Ecology |
description |
WOS:000487521600001 International audience Mass mortalities due to disease outbreaks have recently affected a number of major taxa in marine ecosystems. Climate- and pollution-induced stress may compromise host immune defenses, increasing the risk of opportunistic diseases. Despite growing evidence that mass mortality events affecting marine species worldwide are strongly influenced by the interplay of numerous environmental factors, the reductionist approaches most frequently used to investigate these factors hindered the interpretation of these multifactorial pathologies. In this study, we propose a broader approach based on the combination of RNA-sequencing and 16S microbiota analyses to decipher the factors underlying mass mortality in the striped venus clam, Chamelea gallina, along the Adriatic coast. On one hand, gene expression profiling and functional analyses of microbial communities showed the over-expression of several genes and molecular pathways involved in xenobiotic metabolism, suggesting potential chemical contamination in mortality sites. On the other hand, the down-regulation of several genes involved in immune and stress response, and the over-representation of opportunistic pathogens such as Vibrio and Photobacterium spp. indicates that these microbial species may take advantage of compromised host immune pathways and defense mechanisms that are potentially affected by chemical exposure, resulting in periodic mortality events. We propose the application of our approach to interpret and anticipate the risks inherent in the combined effects of pollutants and microbes on marine animals in today's rapidly changing environment. |
author2 |
Università degli Studi di Padova = University of Padua (Unipd) Laboratoire des Sciences de l'Environnement Marin (LEMAR) (LEMAR) Institut de Recherche pour le Développement (IRD)-Institut Français de Recherche pour l'Exploitation de la Mer (IFREMER)-Université de Brest (UBO)-Institut Universitaire Européen de la Mer (IUEM) Institut de Recherche pour le Développement (IRD)-Institut national des sciences de l'Univers (INSU - CNRS)-Université de Brest (UBO)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD)-Institut national des sciences de l'Univers (INSU - CNRS)-Université de Brest (UBO)-Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS) Università degli Studi di Perugia = University of Perugia (UNIPG) Facoltà di Bioscienze e tecnologie agro-alimentari e ambientali - Faculty of Bioscience and Agro-Food and Environmental Technology Teramo Università degli Studi di Teramo (UniTE) Istituto Zooprofilattico Sperimentale delle Venezie (IZSVe) Università degli Studi di Firenze = University of Florence = Université de Florence (UniFI) |
format |
Article in Journal/Newspaper |
author |
Milan, Massimo Smits, Morgan Dalla Rovere, Giulia Iori, Silvia Zampieri, Angela Carraro, Lisa Martino, Camillo Papetti, Chiara Ianni, Andrea Ferri, Nicola Iannaccone, Marco Patarnello, Tomaso Brunetta, Romina Ciofi, Claudio Grotta, Lisa Arcangeli, Giuseppe Bargelloni, Luca Cardazzo, Barbara Martino, Giuseppe |
author_facet |
Milan, Massimo Smits, Morgan Dalla Rovere, Giulia Iori, Silvia Zampieri, Angela Carraro, Lisa Martino, Camillo Papetti, Chiara Ianni, Andrea Ferri, Nicola Iannaccone, Marco Patarnello, Tomaso Brunetta, Romina Ciofi, Claudio Grotta, Lisa Arcangeli, Giuseppe Bargelloni, Luca Cardazzo, Barbara Martino, Giuseppe |
author_sort |
Milan, Massimo |
title |
Host-microbiota interactions shed light on mortality events in the striped venus clam Chamelea gallina |
title_short |
Host-microbiota interactions shed light on mortality events in the striped venus clam Chamelea gallina |
title_full |
Host-microbiota interactions shed light on mortality events in the striped venus clam Chamelea gallina |
title_fullStr |
Host-microbiota interactions shed light on mortality events in the striped venus clam Chamelea gallina |
title_full_unstemmed |
Host-microbiota interactions shed light on mortality events in the striped venus clam Chamelea gallina |
title_sort |
host-microbiota interactions shed light on mortality events in the striped venus clam chamelea gallina |
publisher |
HAL CCSD |
publishDate |
2019 |
url |
https://hal.science/hal-02873898 https://doi.org/10.1111/mec.15227 |
long_lat |
ENVELOPE(-57.842,-57.842,-61.925,-61.925) |
geographic |
Pacific Venus |
geographic_facet |
Pacific Venus |
genre |
Crassostrea gigas |
genre_facet |
Crassostrea gigas |
op_source |
ISSN: 0962-1083 EISSN: 1365-294X Molecular Ecology https://hal.science/hal-02873898 Molecular Ecology, 2019, 28 (19), pp.4486-4499. ⟨10.1111/mec.15227⟩ |
op_relation |
info:eu-repo/semantics/altIdentifier/doi/10.1111/mec.15227 hal-02873898 https://hal.science/hal-02873898 doi:10.1111/mec.15227 |
op_doi |
https://doi.org/10.1111/mec.15227 |
container_title |
Molecular Ecology |
container_volume |
28 |
container_issue |
19 |
container_start_page |
4486 |
op_container_end_page |
4499 |
_version_ |
1798844913320722432 |
spelling |
ftunivbrest:oai:HAL:hal-02873898v1 2024-05-12T08:02:46+00:00 Host-microbiota interactions shed light on mortality events in the striped venus clam Chamelea gallina Milan, Massimo Smits, Morgan Dalla Rovere, Giulia Iori, Silvia Zampieri, Angela Carraro, Lisa Martino, Camillo Papetti, Chiara Ianni, Andrea Ferri, Nicola Iannaccone, Marco Patarnello, Tomaso Brunetta, Romina Ciofi, Claudio Grotta, Lisa Arcangeli, Giuseppe Bargelloni, Luca Cardazzo, Barbara Martino, Giuseppe Università degli Studi di Padova = University of Padua (Unipd) Laboratoire des Sciences de l'Environnement Marin (LEMAR) (LEMAR) Institut de Recherche pour le Développement (IRD)-Institut Français de Recherche pour l'Exploitation de la Mer (IFREMER)-Université de Brest (UBO)-Institut Universitaire Européen de la Mer (IUEM) Institut de Recherche pour le Développement (IRD)-Institut national des sciences de l'Univers (INSU - CNRS)-Université de Brest (UBO)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD)-Institut national des sciences de l'Univers (INSU - CNRS)-Université de Brest (UBO)-Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS) Università degli Studi di Perugia = University of Perugia (UNIPG) Facoltà di Bioscienze e tecnologie agro-alimentari e ambientali - Faculty of Bioscience and Agro-Food and Environmental Technology Teramo Università degli Studi di Teramo (UniTE) Istituto Zooprofilattico Sperimentale delle Venezie (IZSVe) Università degli Studi di Firenze = University of Florence = Université de Florence (UniFI) 2019 https://hal.science/hal-02873898 https://doi.org/10.1111/mec.15227 en eng HAL CCSD Wiley info:eu-repo/semantics/altIdentifier/doi/10.1111/mec.15227 hal-02873898 https://hal.science/hal-02873898 doi:10.1111/mec.15227 ISSN: 0962-1083 EISSN: 1365-294X Molecular Ecology https://hal.science/hal-02873898 Molecular Ecology, 2019, 28 (19), pp.4486-4499. ⟨10.1111/mec.15227⟩ ACL oncorhynchus-mykiss rainbow-trout bivalve crassostrea-gigas pacific oysters mass mortality transcriptomics vibrio-splendidus adriatic sea damselae subsp damselae haliotis-diversicolor-supertexta host-microbiota interactions immune-response molluscs pollutant-pathogen interactions ssp damselae [SDE.BE]Environmental Sciences/Biodiversity and Ecology info:eu-repo/semantics/article Journal articles 2019 ftunivbrest https://doi.org/10.1111/mec.15227 2024-04-17T23:53:48Z WOS:000487521600001 International audience Mass mortalities due to disease outbreaks have recently affected a number of major taxa in marine ecosystems. Climate- and pollution-induced stress may compromise host immune defenses, increasing the risk of opportunistic diseases. Despite growing evidence that mass mortality events affecting marine species worldwide are strongly influenced by the interplay of numerous environmental factors, the reductionist approaches most frequently used to investigate these factors hindered the interpretation of these multifactorial pathologies. In this study, we propose a broader approach based on the combination of RNA-sequencing and 16S microbiota analyses to decipher the factors underlying mass mortality in the striped venus clam, Chamelea gallina, along the Adriatic coast. On one hand, gene expression profiling and functional analyses of microbial communities showed the over-expression of several genes and molecular pathways involved in xenobiotic metabolism, suggesting potential chemical contamination in mortality sites. On the other hand, the down-regulation of several genes involved in immune and stress response, and the over-representation of opportunistic pathogens such as Vibrio and Photobacterium spp. indicates that these microbial species may take advantage of compromised host immune pathways and defense mechanisms that are potentially affected by chemical exposure, resulting in periodic mortality events. We propose the application of our approach to interpret and anticipate the risks inherent in the combined effects of pollutants and microbes on marine animals in today's rapidly changing environment. Article in Journal/Newspaper Crassostrea gigas Université de Bretagne Occidentale: HAL Pacific Venus ENVELOPE(-57.842,-57.842,-61.925,-61.925) Molecular Ecology 28 19 4486 4499 |