Multiple infections of rodents with zoonotic pathogens in Austria
Rodents are important reservoirs for a large number of zoonotic pathogens. We examined the occurrence of 11 viral, bacterial, and parasitic agents in rodent populations in Austria, including three different hantaviruses, lymphocytic choriomeningitis virus, orthopox virus, Leptospira spp., Borrelia s...
Published in: | Vector-Borne and Zoonotic Diseases |
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Format: | Article in Journal/Newspaper |
Language: | English |
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Mary Ann Liebert
2014
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ftunivbern:oai:boris.unibe.ch:71397 2023-08-20T04:07:59+02:00 Multiple infections of rodents with zoonotic pathogens in Austria Schmidt, Sabrina Essbauer, Sandra S. Mayer-Scholl, Anne Poppert, Sven Schmidt-Chanasit, Jonas Klempa, Boris Henning, Klaus Schares, Gereon Groschup, Martin H. Spitzenberger, Friederike Richter, Dania Heckel, Gerald Ulrich, Rainer G. 2014 application/pdf https://boris.unibe.ch/71397/1/vbz%252E2013%252E1504.pdf https://boris.unibe.ch/71397/ eng eng Mary Ann Liebert https://boris.unibe.ch/71397/ info:eu-repo/semantics/restrictedAccess Schmidt, Sabrina; Essbauer, Sandra S.; Mayer-Scholl, Anne; Poppert, Sven; Schmidt-Chanasit, Jonas; Klempa, Boris; Henning, Klaus; Schares, Gereon; Groschup, Martin H.; Spitzenberger, Friederike; Richter, Dania; Heckel, Gerald; Ulrich, Rainer G. (2014). Multiple infections of rodents with zoonotic pathogens in Austria. Vector-Borne and Zoonotic Diseases, 14(7), pp. 467-475. Mary Ann Liebert 10.1089/vbz.2013.1504 <http://dx.doi.org/10.1089/vbz.2013.1504> 570 Life sciences biology info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion PeerReviewed 2014 ftunivbern https://doi.org/10.1089/vbz.2013.1504 2023-07-31T21:19:38Z Rodents are important reservoirs for a large number of zoonotic pathogens. We examined the occurrence of 11 viral, bacterial, and parasitic agents in rodent populations in Austria, including three different hantaviruses, lymphocytic choriomeningitis virus, orthopox virus, Leptospira spp., Borrelia spp., Rickettsia spp., Bartonella spp., Coxiella burnetii, and Toxoplasma gondii. In 2008, 110 rodents of four species (40 Clethrionomys glareolus, 29 Apodemus flavicollis, 26 Apodemus sylvaticus, and 15 Microtus arvalis) were trapped at two rural sites in Lower Austria. Chest cavity fluid and samples of lung, spleen, kidney, liver, brain, and ear pinna skin were collected. We screened selected tissue samples for hantaviruses, lymphocytic choriomeningitis virus, orthopox viruses, Leptospira, Borrelia, Rickettsia, Bartonella spp., C. burnetii, and T. gondii by RT-PCR/PCR and detected nucleic acids of Tula hantavirus, Leptospira spp., Borrelia afzelii, Rickettsia spp., and different Bartonella species. Serological investigations were performed for hantaviruses, lymphocytic choriomeningitis virus, orthopox viruses, and Rickettsia spp. Here, Dobrava-Belgrade hantavirus-, Tula hantavirus-, lymphocytic choriomeningitis virus-, orthopox virus-, and rickettsia-specific antibodies were demonstrated. Puumala hantavirus, C. burnetii, and T. gondii were neither detected by RT-PCR/PCR nor by serological methods. In addition, multiple infections with up to three pathogens were shown in nine animals of three rodent species from different trapping sites. In conclusion, these results show that rodents in Austria may host multiple zoonotic pathogens. Our observation raises important questions regarding the interactions of different pathogens in the host, the countermeasures of the host's immune system, the impact of the host–pathogen interaction on the fitness of the host, and the spread of infectious agents among wild rodents and from those to other animals or humans. Article in Journal/Newspaper Microtus arvalis BORIS (Bern Open Repository and Information System, University of Bern) Tula ENVELOPE(-65.650,-65.650,-65.517,-65.517) Vector-Borne and Zoonotic Diseases 14 7 467 475 |
institution |
Open Polar |
collection |
BORIS (Bern Open Repository and Information System, University of Bern) |
op_collection_id |
ftunivbern |
language |
English |
topic |
570 Life sciences biology |
spellingShingle |
570 Life sciences biology Schmidt, Sabrina Essbauer, Sandra S. Mayer-Scholl, Anne Poppert, Sven Schmidt-Chanasit, Jonas Klempa, Boris Henning, Klaus Schares, Gereon Groschup, Martin H. Spitzenberger, Friederike Richter, Dania Heckel, Gerald Ulrich, Rainer G. Multiple infections of rodents with zoonotic pathogens in Austria |
topic_facet |
570 Life sciences biology |
description |
Rodents are important reservoirs for a large number of zoonotic pathogens. We examined the occurrence of 11 viral, bacterial, and parasitic agents in rodent populations in Austria, including three different hantaviruses, lymphocytic choriomeningitis virus, orthopox virus, Leptospira spp., Borrelia spp., Rickettsia spp., Bartonella spp., Coxiella burnetii, and Toxoplasma gondii. In 2008, 110 rodents of four species (40 Clethrionomys glareolus, 29 Apodemus flavicollis, 26 Apodemus sylvaticus, and 15 Microtus arvalis) were trapped at two rural sites in Lower Austria. Chest cavity fluid and samples of lung, spleen, kidney, liver, brain, and ear pinna skin were collected. We screened selected tissue samples for hantaviruses, lymphocytic choriomeningitis virus, orthopox viruses, Leptospira, Borrelia, Rickettsia, Bartonella spp., C. burnetii, and T. gondii by RT-PCR/PCR and detected nucleic acids of Tula hantavirus, Leptospira spp., Borrelia afzelii, Rickettsia spp., and different Bartonella species. Serological investigations were performed for hantaviruses, lymphocytic choriomeningitis virus, orthopox viruses, and Rickettsia spp. Here, Dobrava-Belgrade hantavirus-, Tula hantavirus-, lymphocytic choriomeningitis virus-, orthopox virus-, and rickettsia-specific antibodies were demonstrated. Puumala hantavirus, C. burnetii, and T. gondii were neither detected by RT-PCR/PCR nor by serological methods. In addition, multiple infections with up to three pathogens were shown in nine animals of three rodent species from different trapping sites. In conclusion, these results show that rodents in Austria may host multiple zoonotic pathogens. Our observation raises important questions regarding the interactions of different pathogens in the host, the countermeasures of the host's immune system, the impact of the host–pathogen interaction on the fitness of the host, and the spread of infectious agents among wild rodents and from those to other animals or humans. |
format |
Article in Journal/Newspaper |
author |
Schmidt, Sabrina Essbauer, Sandra S. Mayer-Scholl, Anne Poppert, Sven Schmidt-Chanasit, Jonas Klempa, Boris Henning, Klaus Schares, Gereon Groschup, Martin H. Spitzenberger, Friederike Richter, Dania Heckel, Gerald Ulrich, Rainer G. |
author_facet |
Schmidt, Sabrina Essbauer, Sandra S. Mayer-Scholl, Anne Poppert, Sven Schmidt-Chanasit, Jonas Klempa, Boris Henning, Klaus Schares, Gereon Groschup, Martin H. Spitzenberger, Friederike Richter, Dania Heckel, Gerald Ulrich, Rainer G. |
author_sort |
Schmidt, Sabrina |
title |
Multiple infections of rodents with zoonotic pathogens in Austria |
title_short |
Multiple infections of rodents with zoonotic pathogens in Austria |
title_full |
Multiple infections of rodents with zoonotic pathogens in Austria |
title_fullStr |
Multiple infections of rodents with zoonotic pathogens in Austria |
title_full_unstemmed |
Multiple infections of rodents with zoonotic pathogens in Austria |
title_sort |
multiple infections of rodents with zoonotic pathogens in austria |
publisher |
Mary Ann Liebert |
publishDate |
2014 |
url |
https://boris.unibe.ch/71397/1/vbz%252E2013%252E1504.pdf https://boris.unibe.ch/71397/ |
long_lat |
ENVELOPE(-65.650,-65.650,-65.517,-65.517) |
geographic |
Tula |
geographic_facet |
Tula |
genre |
Microtus arvalis |
genre_facet |
Microtus arvalis |
op_source |
Schmidt, Sabrina; Essbauer, Sandra S.; Mayer-Scholl, Anne; Poppert, Sven; Schmidt-Chanasit, Jonas; Klempa, Boris; Henning, Klaus; Schares, Gereon; Groschup, Martin H.; Spitzenberger, Friederike; Richter, Dania; Heckel, Gerald; Ulrich, Rainer G. (2014). Multiple infections of rodents with zoonotic pathogens in Austria. Vector-Borne and Zoonotic Diseases, 14(7), pp. 467-475. Mary Ann Liebert 10.1089/vbz.2013.1504 <http://dx.doi.org/10.1089/vbz.2013.1504> |
op_relation |
https://boris.unibe.ch/71397/ |
op_rights |
info:eu-repo/semantics/restrictedAccess |
op_doi |
https://doi.org/10.1089/vbz.2013.1504 |
container_title |
Vector-Borne and Zoonotic Diseases |
container_volume |
14 |
container_issue |
7 |
container_start_page |
467 |
op_container_end_page |
475 |
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1774719996980625408 |