Pathogenicity, population genetics and dissemination of Bacillus anthracis.

• Published in: Infection, Genetics and Evolution
• Main Authors: Pilo, Paola, Frey, Joachim
• Format: Article in Journal/Newspaper
• Language: English
• Published: Elsevier 2018
• Subjects: 630 Agriculture; Lawrence River; Bering Land Bridge
• Online Access: https://boris.unibe.ch/123633/1/2018%20Anthrax%20Review.pdf; https://boris.unibe.ch/123633/

Bacillus anthracis, the etiological agent of anthrax, procures its particular virulence by a capsule and two AB type toxins: the lethal factor LF and the edema factor EF. These toxins primarily disable immune cells. Both toxins are translocated to the host cell by the adhesin-internalin subunit call...