From notochord to vertebral column: studies on Atlantic salmon (Salmo salar L.)
The notochord initially form a single-cell file stage of chordoblasts covered by a three layered sheath comprising a basal lamina, a main collagenous layer and an external elastic membrane. During early ontogeny, the collagenous layer of the sheath goes through changes in configuration from a circul...
Published in: | Anatomy and Embryology |
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Main Author: | |
Format: | Doctoral or Postdoctoral Thesis |
Language: | English |
Published: |
The University of Bergen
2007
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Subjects: | |
Online Access: | http://hdl.handle.net/1956/2293 |
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ftunivbergen:oai:bora.uib.no:1956/2293 |
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record_format |
openpolar |
institution |
Open Polar |
collection |
University of Bergen: Bergen Open Research Archive (BORA-UiB) |
op_collection_id |
ftunivbergen |
language |
English |
topic |
Notochord Segmentation Vertebral body Ontogenesis Chordacentrum Teleost fish Atlantic salmon Arcocentrum VDP::Matematikk og Naturvitenskap: 400 |
spellingShingle |
Notochord Segmentation Vertebral body Ontogenesis Chordacentrum Teleost fish Atlantic salmon Arcocentrum VDP::Matematikk og Naturvitenskap: 400 Nordvik, Kari From notochord to vertebral column: studies on Atlantic salmon (Salmo salar L.) |
topic_facet |
Notochord Segmentation Vertebral body Ontogenesis Chordacentrum Teleost fish Atlantic salmon Arcocentrum VDP::Matematikk og Naturvitenskap: 400 |
description |
The notochord initially form a single-cell file stage of chordoblasts covered by a three layered sheath comprising a basal lamina, a main collagenous layer and an external elastic membrane. During early ontogeny, the collagenous layer of the sheath goes through changes in configuration from a circular orientation, with fibres oriented perpendicular to the long axis, and to a lamellar organization where alternating layers of parallel collagen fibres form helices, with a tangent angle of 75-80° to the long axis. The shift in collagen arrangement is taking place shortly after hatching and may reflect an adaptation of the notochord to functional demands related to stage of development. The serrated surfaces of the elastica externa encasing the notochord seem to provide an interconnection between the notochord and the myosepta, with a function related to transmission of force from the musculature. The subsequent segmentation process leading to formation of vertebral and intervertebral regions seems to be initiated within the notochord through formation of cellular chordoblast segments. Formation of the cellular segments is closely followed by a segmental pattern of ALP activity within the chordoblast layer and formation of mineralized chordacentra within the collagenous layer of the notochord sheath. Development of the vertebral column thus seem to involve a dual segmentation where notochord derived chordacentra define the vertebral segments and the sclerotome external to the notochord provide further growth to the vertebrae. The salmon vertebral column comprises notochord and sclerotome derived structures that tightly interconnect the vertebrae and the intervertebral regions. There are four distinct layers of bone and mineralized tissues that form the vertebral body. The two inner layers comprise the chordacentrum (mineralization of the notochord sheath) and the inner layer of the amphicoel (mineralization of the intervertebral ligament). The third layer is deposited by osteoblasts, forming the main portion of the ... |
format |
Doctoral or Postdoctoral Thesis |
author |
Nordvik, Kari |
author_facet |
Nordvik, Kari |
author_sort |
Nordvik, Kari |
title |
From notochord to vertebral column: studies on Atlantic salmon (Salmo salar L.) |
title_short |
From notochord to vertebral column: studies on Atlantic salmon (Salmo salar L.) |
title_full |
From notochord to vertebral column: studies on Atlantic salmon (Salmo salar L.) |
title_fullStr |
From notochord to vertebral column: studies on Atlantic salmon (Salmo salar L.) |
title_full_unstemmed |
From notochord to vertebral column: studies on Atlantic salmon (Salmo salar L.) |
title_sort |
from notochord to vertebral column: studies on atlantic salmon (salmo salar l.) |
publisher |
The University of Bergen |
publishDate |
2007 |
url |
http://hdl.handle.net/1956/2293 |
genre |
Atlantic salmon Salmo salar |
genre_facet |
Atlantic salmon Salmo salar |
op_relation |
Paper I: Anatomy and Embryology 207, Grotmol, S.; Kryvi, K.; Nordvik, K.; Totland, G. K.; Notochord segmentation may lay down the pathway for the development of the vertebral bodies in the Atlantic salmon, pp. 263-272. Copyright 2003 Springer-Verlag. Full-text not available in Bora due to publisher restrictions. http://dx.doi.org/10.1007/s00429-003-0349-y Paper II: Journal of Anatomy 206, Grotmol, S.; Nordvik, K.; Kryvi, H.; Totland, G. K.; A segmental pattern of alkaline phosphatase activity within the notochord coincides with the initial formation of the vertebral bodies, pp. 427-436. Copyright 2005 Blackwell Publishing. Full-text not available in Bora due to publisher restrictions. http://dx.doi.org/10.1111/j.1469-7580.2005.00408.x Paper III: Journal of Anatomy 206, Nordvik, K.; Kryvi, H.; Totland, G. K.; Grotmol, S.; The salmon vertebral body develops through mineralization of two preformed tissues that are encompassed by two layers of bone, pp. 103-114. Copyright 2005 Blackwell Publishing. Abstract only. Full-text not available in Bora due to publisher restrictions. http://dx.doi.org/10.1007/s00429-003-0349-y Paper IV: Journal of Anatomy 209, Grotmol, S.; Kryvi, K.; Keynes, R.; Krossøy, C.; Nordvik, K.; Totland, G. K.; Stepwise enforcement of the notochord and its intersection with the myoseptum: an evolutionary path leading to development of the vertebra?, pp. 339-357. Copyright 2006 Blackwell Publishing. Full-text not available in Bora due to publisher restrictions. http://dx.doi.org/ 10.1111/j.1469-7580.2006.00618.x urn:isbn:978-82-308-0367-7 (print version) http://hdl.handle.net/1956/2293 |
op_doi |
https://doi.org/10.1007/s00429-003-0349-y10.1111/j.1469-7580.2005.00408.x |
container_title |
Anatomy and Embryology |
container_volume |
207 |
container_issue |
4-5 |
container_start_page |
263 |
op_container_end_page |
272 |
_version_ |
1766362513280073728 |
spelling |
ftunivbergen:oai:bora.uib.no:1956/2293 2023-05-15T15:32:01+02:00 From notochord to vertebral column: studies on Atlantic salmon (Salmo salar L.) Nordvik, Kari 2007-05-11 application/pdf http://hdl.handle.net/1956/2293 eng eng The University of Bergen Paper I: Anatomy and Embryology 207, Grotmol, S.; Kryvi, K.; Nordvik, K.; Totland, G. K.; Notochord segmentation may lay down the pathway for the development of the vertebral bodies in the Atlantic salmon, pp. 263-272. Copyright 2003 Springer-Verlag. Full-text not available in Bora due to publisher restrictions. http://dx.doi.org/10.1007/s00429-003-0349-y Paper II: Journal of Anatomy 206, Grotmol, S.; Nordvik, K.; Kryvi, H.; Totland, G. K.; A segmental pattern of alkaline phosphatase activity within the notochord coincides with the initial formation of the vertebral bodies, pp. 427-436. Copyright 2005 Blackwell Publishing. Full-text not available in Bora due to publisher restrictions. http://dx.doi.org/10.1111/j.1469-7580.2005.00408.x Paper III: Journal of Anatomy 206, Nordvik, K.; Kryvi, H.; Totland, G. K.; Grotmol, S.; The salmon vertebral body develops through mineralization of two preformed tissues that are encompassed by two layers of bone, pp. 103-114. Copyright 2005 Blackwell Publishing. Abstract only. Full-text not available in Bora due to publisher restrictions. http://dx.doi.org/10.1007/s00429-003-0349-y Paper IV: Journal of Anatomy 209, Grotmol, S.; Kryvi, K.; Keynes, R.; Krossøy, C.; Nordvik, K.; Totland, G. K.; Stepwise enforcement of the notochord and its intersection with the myoseptum: an evolutionary path leading to development of the vertebra?, pp. 339-357. Copyright 2006 Blackwell Publishing. Full-text not available in Bora due to publisher restrictions. http://dx.doi.org/ 10.1111/j.1469-7580.2006.00618.x urn:isbn:978-82-308-0367-7 (print version) http://hdl.handle.net/1956/2293 Notochord Segmentation Vertebral body Ontogenesis Chordacentrum Teleost fish Atlantic salmon Arcocentrum VDP::Matematikk og Naturvitenskap: 400 Doctoral thesis 2007 ftunivbergen https://doi.org/10.1007/s00429-003-0349-y10.1111/j.1469-7580.2005.00408.x 2023-03-14T17:41:26Z The notochord initially form a single-cell file stage of chordoblasts covered by a three layered sheath comprising a basal lamina, a main collagenous layer and an external elastic membrane. During early ontogeny, the collagenous layer of the sheath goes through changes in configuration from a circular orientation, with fibres oriented perpendicular to the long axis, and to a lamellar organization where alternating layers of parallel collagen fibres form helices, with a tangent angle of 75-80° to the long axis. The shift in collagen arrangement is taking place shortly after hatching and may reflect an adaptation of the notochord to functional demands related to stage of development. The serrated surfaces of the elastica externa encasing the notochord seem to provide an interconnection between the notochord and the myosepta, with a function related to transmission of force from the musculature. The subsequent segmentation process leading to formation of vertebral and intervertebral regions seems to be initiated within the notochord through formation of cellular chordoblast segments. Formation of the cellular segments is closely followed by a segmental pattern of ALP activity within the chordoblast layer and formation of mineralized chordacentra within the collagenous layer of the notochord sheath. Development of the vertebral column thus seem to involve a dual segmentation where notochord derived chordacentra define the vertebral segments and the sclerotome external to the notochord provide further growth to the vertebrae. The salmon vertebral column comprises notochord and sclerotome derived structures that tightly interconnect the vertebrae and the intervertebral regions. There are four distinct layers of bone and mineralized tissues that form the vertebral body. The two inner layers comprise the chordacentrum (mineralization of the notochord sheath) and the inner layer of the amphicoel (mineralization of the intervertebral ligament). The third layer is deposited by osteoblasts, forming the main portion of the ... Doctoral or Postdoctoral Thesis Atlantic salmon Salmo salar University of Bergen: Bergen Open Research Archive (BORA-UiB) Anatomy and Embryology 207 4-5 263 272 |