Induction of tenacibaculosis in Atlantic salmon smolts using Tenacibaculum finnmarkense and the evaluation of a whole cell inactivated vaccine
Tenacibaculosis, an ulcerative disease characterised by skin lesions, mouth erosion, frayed fins and tail rot, is a significant fish welfare issue in marine aquaculture worldwide. The disease is a concern to the Atlantic salmon farming industry due to mortality losses and the use of antibiotics. The...
Published in: | Aquaculture |
---|---|
Main Authors: | , , , , , , , , , , |
Format: | Article in Journal/Newspaper |
Language: | English |
Published: |
Elsevier
2018
|
Subjects: | |
Online Access: | http://hdl.handle.net/1956/19439 https://doi.org/10.1016/j.aquaculture.2018.06.063 |
id |
ftunivbergen:oai:bora.uib.no:1956/19439 |
---|---|
record_format |
openpolar |
spelling |
ftunivbergen:oai:bora.uib.no:1956/19439 2023-05-15T15:31:34+02:00 Induction of tenacibaculosis in Atlantic salmon smolts using Tenacibaculum finnmarkense and the evaluation of a whole cell inactivated vaccine Småge, Sverre Bang Frisch, Kathleen Marie Vold, Vidar Duesund, Henrik Brevik, Øyvind Jakobsen Olsen, Rolf Hetlelid Sjaatil, Stine Klevan, Are Brudeseth, Bjørn Watanabe, Kuninori Nylund, Are 2018-10 application/pdf http://hdl.handle.net/1956/19439 https://doi.org/10.1016/j.aquaculture.2018.06.063 eng eng Elsevier urn:issn:0044-8486 http://hdl.handle.net/1956/19439 https://doi.org/10.1016/j.aquaculture.2018.06.063 cristin:1651443 Attribution CC BY http://creativecommons.org/licenses/by/4.0 Copyright 2018 The Author(s) Aquaculture 495 858-864 Peer reviewed Journal article 2018 ftunivbergen https://doi.org/10.1016/j.aquaculture.2018.06.063 2023-03-14T17:43:19Z Tenacibaculosis, an ulcerative disease characterised by skin lesions, mouth erosion, frayed fins and tail rot, is a significant fish welfare issue in marine aquaculture worldwide. The disease is a concern to the Atlantic salmon farming industry due to mortality losses and the use of antibiotics. The most commonly isolated bacterium from Northern Norwegian salmon farms during tenacibaculosis outbreaks is Tenacibaculum finnmarkense; however it has not been shown to be the causative agent. This study investigates the role of T. finnmarkense and closely related strains as the possible agent of tenacibaculosis in smolts recently transferred into seawater. The efficacy of whole cell inactivated vaccines using T. finnmarkense was also investigated using the developed challenge model. The results show that T. finnmarkense strain HFJT and strain Tsp.2 are causative agents of tenacibaculosis as it presents in Northern Norway without the need for any pre-stressor or co-infection, and that different strains vary in pathogenicity. The pathogen does not appear to spread easily from fish to fish and more work is therefore required to determine possible reservoirs and/or vectors. Even though a whole cell inactivated vaccine using T. finnmarkense strain HFJT induces an antibody response, this study did not manage to show any protection against tenacibaculosis induced through a bath infection. Future studies need to include determining pathogen-host interactions and identifying possible antigens for vaccine candidates. publishedVersion Article in Journal/Newspaper Atlantic salmon Northern Norway University of Bergen: Bergen Open Research Archive (BORA-UiB) Norway Aquaculture 495 858 864 |
institution |
Open Polar |
collection |
University of Bergen: Bergen Open Research Archive (BORA-UiB) |
op_collection_id |
ftunivbergen |
language |
English |
description |
Tenacibaculosis, an ulcerative disease characterised by skin lesions, mouth erosion, frayed fins and tail rot, is a significant fish welfare issue in marine aquaculture worldwide. The disease is a concern to the Atlantic salmon farming industry due to mortality losses and the use of antibiotics. The most commonly isolated bacterium from Northern Norwegian salmon farms during tenacibaculosis outbreaks is Tenacibaculum finnmarkense; however it has not been shown to be the causative agent. This study investigates the role of T. finnmarkense and closely related strains as the possible agent of tenacibaculosis in smolts recently transferred into seawater. The efficacy of whole cell inactivated vaccines using T. finnmarkense was also investigated using the developed challenge model. The results show that T. finnmarkense strain HFJT and strain Tsp.2 are causative agents of tenacibaculosis as it presents in Northern Norway without the need for any pre-stressor or co-infection, and that different strains vary in pathogenicity. The pathogen does not appear to spread easily from fish to fish and more work is therefore required to determine possible reservoirs and/or vectors. Even though a whole cell inactivated vaccine using T. finnmarkense strain HFJT induces an antibody response, this study did not manage to show any protection against tenacibaculosis induced through a bath infection. Future studies need to include determining pathogen-host interactions and identifying possible antigens for vaccine candidates. publishedVersion |
format |
Article in Journal/Newspaper |
author |
Småge, Sverre Bang Frisch, Kathleen Marie Vold, Vidar Duesund, Henrik Brevik, Øyvind Jakobsen Olsen, Rolf Hetlelid Sjaatil, Stine Klevan, Are Brudeseth, Bjørn Watanabe, Kuninori Nylund, Are |
spellingShingle |
Småge, Sverre Bang Frisch, Kathleen Marie Vold, Vidar Duesund, Henrik Brevik, Øyvind Jakobsen Olsen, Rolf Hetlelid Sjaatil, Stine Klevan, Are Brudeseth, Bjørn Watanabe, Kuninori Nylund, Are Induction of tenacibaculosis in Atlantic salmon smolts using Tenacibaculum finnmarkense and the evaluation of a whole cell inactivated vaccine |
author_facet |
Småge, Sverre Bang Frisch, Kathleen Marie Vold, Vidar Duesund, Henrik Brevik, Øyvind Jakobsen Olsen, Rolf Hetlelid Sjaatil, Stine Klevan, Are Brudeseth, Bjørn Watanabe, Kuninori Nylund, Are |
author_sort |
Småge, Sverre Bang |
title |
Induction of tenacibaculosis in Atlantic salmon smolts using Tenacibaculum finnmarkense and the evaluation of a whole cell inactivated vaccine |
title_short |
Induction of tenacibaculosis in Atlantic salmon smolts using Tenacibaculum finnmarkense and the evaluation of a whole cell inactivated vaccine |
title_full |
Induction of tenacibaculosis in Atlantic salmon smolts using Tenacibaculum finnmarkense and the evaluation of a whole cell inactivated vaccine |
title_fullStr |
Induction of tenacibaculosis in Atlantic salmon smolts using Tenacibaculum finnmarkense and the evaluation of a whole cell inactivated vaccine |
title_full_unstemmed |
Induction of tenacibaculosis in Atlantic salmon smolts using Tenacibaculum finnmarkense and the evaluation of a whole cell inactivated vaccine |
title_sort |
induction of tenacibaculosis in atlantic salmon smolts using tenacibaculum finnmarkense and the evaluation of a whole cell inactivated vaccine |
publisher |
Elsevier |
publishDate |
2018 |
url |
http://hdl.handle.net/1956/19439 https://doi.org/10.1016/j.aquaculture.2018.06.063 |
geographic |
Norway |
geographic_facet |
Norway |
genre |
Atlantic salmon Northern Norway |
genre_facet |
Atlantic salmon Northern Norway |
op_source |
Aquaculture 495 858-864 |
op_relation |
urn:issn:0044-8486 http://hdl.handle.net/1956/19439 https://doi.org/10.1016/j.aquaculture.2018.06.063 cristin:1651443 |
op_rights |
Attribution CC BY http://creativecommons.org/licenses/by/4.0 Copyright 2018 The Author(s) |
op_doi |
https://doi.org/10.1016/j.aquaculture.2018.06.063 |
container_title |
Aquaculture |
container_volume |
495 |
container_start_page |
858 |
op_container_end_page |
864 |
_version_ |
1766362089788538880 |