Clinical remission of asthma and allergic rhinitis-in a longitudinal population study

Background: Although asthma and allergic rhinitis are chronic diseases, some patients experience periods of remission. Information on prognostic factors associated with the remission of asthma and allergic rhinitis is valuable in resource prioritization. This study investigated factors associated wi...

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Published in:Journal of Asthma and Allergy
Main Authors: Heldin, Johanna, Malinovschi, Andrei, Johannessen, Ane, Alving, Kjell, Holm, Mathias, Franklin, Karl A., Forsberg, Bertil, Schlünssen, Vivi, Jögi, Rain, Gislason, Thorarinn, Benediktsdottir, Bryndis, Svanes, Cecilie, Janson, Christer
Format: Article in Journal/Newspaper
Language:English
Published: DovePress 2022
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Online Access:https://hdl.handle.net/11250/3040095
https://doi.org/10.2147/JAA.S378584
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spelling ftunivbergen:oai:bora.uib.no:11250/3040095 2023-05-15T16:52:11+02:00 Clinical remission of asthma and allergic rhinitis-in a longitudinal population study Heldin, Johanna Malinovschi, Andrei Johannessen, Ane Alving, Kjell Holm, Mathias Franklin, Karl A. Forsberg, Bertil Schlünssen, Vivi Jögi, Rain Gislason, Thorarinn Benediktsdottir, Bryndis Svanes, Cecilie Janson, Christer 2022 application/pdf https://hdl.handle.net/11250/3040095 https://doi.org/10.2147/JAA.S378584 eng eng DovePress urn:issn:1178-6965 https://hdl.handle.net/11250/3040095 https://doi.org/10.2147/JAA.S378584 cristin:2081674 Journal of Asthma and Allergy. 2022, 15, 1569-1578. Navngivelse-Ikkekommersiell 4.0 Internasjonal http://creativecommons.org/licenses/by-nc/4.0/deed.no Copyright 2022 The Author(s) Journal of Asthma and Allergy 1569-1578 15 Journal article Peer reviewed 2022 ftunivbergen https://doi.org/10.2147/JAA.S378584 2023-03-14T17:43:55Z Background: Although asthma and allergic rhinitis are chronic diseases, some patients experience periods of remission. Information on prognostic factors associated with the remission of asthma and allergic rhinitis is valuable in resource prioritization. This study investigated factors associated with the clinical remission of asthma and allergic rhinitis. Methods: In the Respiratory Health In Northern Europe (RHINE) study, data was collected with questionnaires in stage one (RHINE I, 1989– 1992) and two follow-ups (RHINE II, 1999– 2001 and RHINE III, 2010– 2012) from Sweden, Norway, Denmark, Iceland and Estonia. Clinical remission was defined as having reported asthma or allergic rhinitis in RHINE I or RHINE II but not in RHINE III. Results: Of 13,052 participants, 975 (7.5%) reported asthma in RHINE I or RHINE II, and 3379 (25.9%) allergic rhinitis. Clinical remission of asthma and allergic rhinitis was found in 46.4% and 31.8%, respectively. Living in Estonia (OR (95% CI) 2.44 (1.22– 4.85)) and living in an apartment (1.45 (1.06– 1.98)) were related to remission of asthma, while subjects reporting allergic rhinitis (0.68 (0.51– 0.90)), asthma onset ≤ 12 years of age (0.49 (0.35– 0.68)), receiving treatment with antibiotics for respiratory illness (0.64 (0.47– 0.87)) were less likely to have asthma remission. Factors related to a higher likelihood of remission of allergic rhinitis were no asthma at baseline, age ≥ 58 years in RHINE III, allergic rhinitis onset after 12 years of age, living in rural areas as a child, having only a primary school education and not being pregnant. Conclusion: Clinical remission was found in almost one-half of those with asthma and one-third of persons with allergic rhinitis. Coexisting allergic symptoms were associated with less clinical asthma remission. Age, asthma symptoms and environmental factors in childhood, such as living in a rural area, were found to influence the clinical remission of allergic rhinitis. publishedVersion Article in Journal/Newspaper Iceland University of Bergen: Bergen Open Research Archive (BORA-UiB) Norway Journal of Asthma and Allergy Volume 15 1569 1578
institution Open Polar
collection University of Bergen: Bergen Open Research Archive (BORA-UiB)
op_collection_id ftunivbergen
language English
description Background: Although asthma and allergic rhinitis are chronic diseases, some patients experience periods of remission. Information on prognostic factors associated with the remission of asthma and allergic rhinitis is valuable in resource prioritization. This study investigated factors associated with the clinical remission of asthma and allergic rhinitis. Methods: In the Respiratory Health In Northern Europe (RHINE) study, data was collected with questionnaires in stage one (RHINE I, 1989– 1992) and two follow-ups (RHINE II, 1999– 2001 and RHINE III, 2010– 2012) from Sweden, Norway, Denmark, Iceland and Estonia. Clinical remission was defined as having reported asthma or allergic rhinitis in RHINE I or RHINE II but not in RHINE III. Results: Of 13,052 participants, 975 (7.5%) reported asthma in RHINE I or RHINE II, and 3379 (25.9%) allergic rhinitis. Clinical remission of asthma and allergic rhinitis was found in 46.4% and 31.8%, respectively. Living in Estonia (OR (95% CI) 2.44 (1.22– 4.85)) and living in an apartment (1.45 (1.06– 1.98)) were related to remission of asthma, while subjects reporting allergic rhinitis (0.68 (0.51– 0.90)), asthma onset ≤ 12 years of age (0.49 (0.35– 0.68)), receiving treatment with antibiotics for respiratory illness (0.64 (0.47– 0.87)) were less likely to have asthma remission. Factors related to a higher likelihood of remission of allergic rhinitis were no asthma at baseline, age ≥ 58 years in RHINE III, allergic rhinitis onset after 12 years of age, living in rural areas as a child, having only a primary school education and not being pregnant. Conclusion: Clinical remission was found in almost one-half of those with asthma and one-third of persons with allergic rhinitis. Coexisting allergic symptoms were associated with less clinical asthma remission. Age, asthma symptoms and environmental factors in childhood, such as living in a rural area, were found to influence the clinical remission of allergic rhinitis. publishedVersion
format Article in Journal/Newspaper
author Heldin, Johanna
Malinovschi, Andrei
Johannessen, Ane
Alving, Kjell
Holm, Mathias
Franklin, Karl A.
Forsberg, Bertil
Schlünssen, Vivi
Jögi, Rain
Gislason, Thorarinn
Benediktsdottir, Bryndis
Svanes, Cecilie
Janson, Christer
spellingShingle Heldin, Johanna
Malinovschi, Andrei
Johannessen, Ane
Alving, Kjell
Holm, Mathias
Franklin, Karl A.
Forsberg, Bertil
Schlünssen, Vivi
Jögi, Rain
Gislason, Thorarinn
Benediktsdottir, Bryndis
Svanes, Cecilie
Janson, Christer
Clinical remission of asthma and allergic rhinitis-in a longitudinal population study
author_facet Heldin, Johanna
Malinovschi, Andrei
Johannessen, Ane
Alving, Kjell
Holm, Mathias
Franklin, Karl A.
Forsberg, Bertil
Schlünssen, Vivi
Jögi, Rain
Gislason, Thorarinn
Benediktsdottir, Bryndis
Svanes, Cecilie
Janson, Christer
author_sort Heldin, Johanna
title Clinical remission of asthma and allergic rhinitis-in a longitudinal population study
title_short Clinical remission of asthma and allergic rhinitis-in a longitudinal population study
title_full Clinical remission of asthma and allergic rhinitis-in a longitudinal population study
title_fullStr Clinical remission of asthma and allergic rhinitis-in a longitudinal population study
title_full_unstemmed Clinical remission of asthma and allergic rhinitis-in a longitudinal population study
title_sort clinical remission of asthma and allergic rhinitis-in a longitudinal population study
publisher DovePress
publishDate 2022
url https://hdl.handle.net/11250/3040095
https://doi.org/10.2147/JAA.S378584
geographic Norway
geographic_facet Norway
genre Iceland
genre_facet Iceland
op_source Journal of Asthma and Allergy
1569-1578
15
op_relation urn:issn:1178-6965
https://hdl.handle.net/11250/3040095
https://doi.org/10.2147/JAA.S378584
cristin:2081674
Journal of Asthma and Allergy. 2022, 15, 1569-1578.
op_rights Navngivelse-Ikkekommersiell 4.0 Internasjonal
http://creativecommons.org/licenses/by-nc/4.0/deed.no
Copyright 2022 The Author(s)
op_doi https://doi.org/10.2147/JAA.S378584
container_title Journal of Asthma and Allergy
container_volume Volume 15
container_start_page 1569
op_container_end_page 1578
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