Rossinones A and B, biologically active meroterpenoids from the Antarctic Ascidian, aplidium species

Rossinones A (1) and B (2), biologically active meroterpene derivatives, were isolated from an Antarctic collection of the ascidian Aplidium species and structurally characterized with spectroscopic methods. The absolute configuration of 1 was deduced by using the modified Mosher method. The rossino...

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Bibliographic Details
Published in:The Journal of Organic Chemistry
Main Authors: Appleton, DR, Chuen, CS, Berridge, MV, Webb, VL, Copp, BR
Format: Article in Journal/Newspaper
Language:English
Published: AMER CHEMICAL SOC 2009
Subjects:
NEUTROPHIL RESPIRATORY BURST
NATURAL-PRODUCTS
KIGELIA-PINNATA
PALMEROLIDE-A
ALKALOIDS
METABOLITES
DERIVATIVES
INHIBITORS
AGENTS
Antarctic
The Antarctic
Antarc*
Online Access:http://hdl.handle.net/2292/8372
https://doi.org/10.1021/jo901846j
Description
Summary:Rossinones A (1) and B (2), biologically active meroterpene derivatives, were isolated from an Antarctic collection of the ascidian Aplidium species and structurally characterized with spectroscopic methods. The absolute configuration of 1 was deduced by using the modified Mosher method. The rossinones exhibit anti-inflammatory, antiviral and antiproliferative activities.

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