European Surveillance of Antimicrobial Consumption (ESAC): outpatient parenteral antibiotic treatment in Europe
Abstract: Objectives: To assess the proportion of parenteral treatment of the total outpatient antibiotic use in Europe, and to identify the antibiotic groups and individual antibiotics most commonly administered in this way. Methods: Within the European Surveillance of Antimicrobial Consumption (ES...
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ftunivantwerpen:c:irua:75818 2024-10-06T13:50:04+00:00 European Surveillance of Antimicrobial Consumption (ESAC): outpatient parenteral antibiotic treatment in Europe Coenen, Samuel Muller, Arno Adriaenssens, Niels Vankerckhoven, Vanessa Hendrickx, Erik Goossens, Herman ESAC Project Group 2009 pdf https://hdl.handle.net/10067/758180151162165141 eng eng info:eu-repo/semantics/altIdentifier/isi/000266962100031 info:eu-repo/semantics/altIdentifier/doi/10.1093/JAC/DKP135 info:eu-repo/semantics/closedAccess 0305-7453 The journal of antimicrobial chemotherapy Human medicine info:eu-repo/semantics/article 2009 ftunivantwerpen https://doi.org/10.1093/JAC/DKP135 2024-09-10T04:06:32Z Abstract: Objectives: To assess the proportion of parenteral treatment of the total outpatient antibiotic use in Europe, and to identify the antibiotic groups and individual antibiotics most commonly administered in this way. Methods: Within the European Surveillance of Antimicrobial Consumption (ESAC; www.esac.ua.ac.be), using the anatomic therapeutic chemical (ATC) and defined daily dose (DDD) classification, data on outpatient use of antibacterials for systemic use (ATC J01), aggregated at the level of the active substance and expressed in DDD per 1000 inhabitants per day (DID; WHO version 2007), were extracted for 2006 by route of administration and by country. Parenteral use was expressed as a percentage of the total outpatient use in DID. Results: In 20 European countries, the total outpatient antibiotic use ranged from 27.91 DID in France to 9.58 DID in Russia. The proportion of outpatient parenteral antibiotic treatment ranged from 6.75% in Russia to 0.001% in Iceland. The three most commonly used antibiotic groups for parenteral treatment in Europe were the cephalosporins (J01D; 44.58%), the aminoglycosides (J01G; 25.27%) and the penicillins (J01C; 17.78%). Four antibiotics [gentamicin (J01GB03) 18.53%; ceftriaxone (J01DD04) 17.85%; cefazolin (J01DB04) 13.16%; and lincomycin (J01FF02) 5.47%] represented more than half of the use. Conclusions: In all 20 European countries studied together, 2.04% of outpatient antibiotics were used for parenteral treatment. However, as for the total outpatient antibiotic use and the use of different antibiotic groups and antibiotics, there is a striking variation in the proportions of parenteral antibiotic use in Europe. More in-depth data on outpatient antibiotic use are needed to explain this variation. Article in Journal/Newspaper Iceland IRUA - Institutional Repository van de Universiteit Antwerpen Journal of Antimicrobial Chemotherapy 64 1 200 205 |
institution |
Open Polar |
collection |
IRUA - Institutional Repository van de Universiteit Antwerpen |
op_collection_id |
ftunivantwerpen |
language |
English |
topic |
Human medicine |
spellingShingle |
Human medicine Coenen, Samuel Muller, Arno Adriaenssens, Niels Vankerckhoven, Vanessa Hendrickx, Erik Goossens, Herman European Surveillance of Antimicrobial Consumption (ESAC): outpatient parenteral antibiotic treatment in Europe |
topic_facet |
Human medicine |
description |
Abstract: Objectives: To assess the proportion of parenteral treatment of the total outpatient antibiotic use in Europe, and to identify the antibiotic groups and individual antibiotics most commonly administered in this way. Methods: Within the European Surveillance of Antimicrobial Consumption (ESAC; www.esac.ua.ac.be), using the anatomic therapeutic chemical (ATC) and defined daily dose (DDD) classification, data on outpatient use of antibacterials for systemic use (ATC J01), aggregated at the level of the active substance and expressed in DDD per 1000 inhabitants per day (DID; WHO version 2007), were extracted for 2006 by route of administration and by country. Parenteral use was expressed as a percentage of the total outpatient use in DID. Results: In 20 European countries, the total outpatient antibiotic use ranged from 27.91 DID in France to 9.58 DID in Russia. The proportion of outpatient parenteral antibiotic treatment ranged from 6.75% in Russia to 0.001% in Iceland. The three most commonly used antibiotic groups for parenteral treatment in Europe were the cephalosporins (J01D; 44.58%), the aminoglycosides (J01G; 25.27%) and the penicillins (J01C; 17.78%). Four antibiotics [gentamicin (J01GB03) 18.53%; ceftriaxone (J01DD04) 17.85%; cefazolin (J01DB04) 13.16%; and lincomycin (J01FF02) 5.47%] represented more than half of the use. Conclusions: In all 20 European countries studied together, 2.04% of outpatient antibiotics were used for parenteral treatment. However, as for the total outpatient antibiotic use and the use of different antibiotic groups and antibiotics, there is a striking variation in the proportions of parenteral antibiotic use in Europe. More in-depth data on outpatient antibiotic use are needed to explain this variation. |
author2 |
ESAC Project Group |
format |
Article in Journal/Newspaper |
author |
Coenen, Samuel Muller, Arno Adriaenssens, Niels Vankerckhoven, Vanessa Hendrickx, Erik Goossens, Herman |
author_facet |
Coenen, Samuel Muller, Arno Adriaenssens, Niels Vankerckhoven, Vanessa Hendrickx, Erik Goossens, Herman |
author_sort |
Coenen, Samuel |
title |
European Surveillance of Antimicrobial Consumption (ESAC): outpatient parenteral antibiotic treatment in Europe |
title_short |
European Surveillance of Antimicrobial Consumption (ESAC): outpatient parenteral antibiotic treatment in Europe |
title_full |
European Surveillance of Antimicrobial Consumption (ESAC): outpatient parenteral antibiotic treatment in Europe |
title_fullStr |
European Surveillance of Antimicrobial Consumption (ESAC): outpatient parenteral antibiotic treatment in Europe |
title_full_unstemmed |
European Surveillance of Antimicrobial Consumption (ESAC): outpatient parenteral antibiotic treatment in Europe |
title_sort |
european surveillance of antimicrobial consumption (esac): outpatient parenteral antibiotic treatment in europe |
publishDate |
2009 |
url |
https://hdl.handle.net/10067/758180151162165141 |
genre |
Iceland |
genre_facet |
Iceland |
op_source |
0305-7453 The journal of antimicrobial chemotherapy |
op_relation |
info:eu-repo/semantics/altIdentifier/isi/000266962100031 info:eu-repo/semantics/altIdentifier/doi/10.1093/JAC/DKP135 |
op_rights |
info:eu-repo/semantics/closedAccess |
op_doi |
https://doi.org/10.1093/JAC/DKP135 |
container_title |
Journal of Antimicrobial Chemotherapy |
container_volume |
64 |
container_issue |
1 |
container_start_page |
200 |
op_container_end_page |
205 |
_version_ |
1812178143408029696 |