Physiological effects of PFAS exposure in seabird chicks : a multi-species study of thyroid hormone triiodothyronine, body condition and telomere length in South Western France
Abstract: There is growing evidence that poly and perfluoroalkyl substances (PFAS) exposure leads to the disruption of thyroid hormones including thyroxine (T4) and triiodothyronine (T3), and may affect telomeres, repetitive nucleotide sequences which protect chromosome ends. Many seabird species ar...
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Online Access: | https://hdl.handle.net/10067/1992950151162165141 https://repository.uantwerpen.be/docstore/d:irua:19666 |
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ftunivantwerpen:c:irua:199295 2024-05-19T07:43:42+00:00 Physiological effects of PFAS exposure in seabird chicks : a multi-species study of thyroid hormone triiodothyronine, body condition and telomere length in South Western France Sebastiano, Manrico Jouanneau, W. Blevin, P. Angelier, F. Pallud, M. Ribout, C. Gernigon, J. Lemesle, J.C. Robin, F. Pardon, P. Budzinski, H. Labadie, P. Chastel, O. 2023 https://hdl.handle.net/10067/1992950151162165141 https://repository.uantwerpen.be/docstore/d:irua:19666 eng eng info:eu-repo/semantics/altIdentifier/doi/10.1016/J.SCITOTENV.2023.165920 info:eu-repo/semantics/altIdentifier/isi/001066220700001 info:eu-repo/semantics/openAccess 0048-9697 The science of the total environment Chemistry Biology info:eu-repo/semantics/article 2023 ftunivantwerpen https://doi.org/10.1016/J.SCITOTENV.2023.165920 2024-05-01T00:01:06Z Abstract: There is growing evidence that poly and perfluoroalkyl substances (PFAS) exposure leads to the disruption of thyroid hormones including thyroxine (T4) and triiodothyronine (T3), and may affect telomeres, repetitive nucleotide sequences which protect chromosome ends. Many seabird species are long-lived top predators thus exhibit high contaminant levels, and PFAS-disrupting effects on their physiology have been documented especially in relation to the endocrine system in adults. On the contrary, studies on the developmental period (i.e., chicks), during which exposure to environmental contaminants may have a greater impact on physiological traits, remain scarce to this date. We carried out a multi-species study with the aim to assess whether and to which extent chicks of four gull species (herring gull, great and lesser black-backed gull, yellow-legged gull) in South Western France are contaminated by PFAS, and to bring further evidence about their potential physiological consequences. Linear PFOS showed concentrations of concern as it was generally >10 times higher than the other PFAS, and exceeded a threshold toxicity level (calculated from previous studies in birds) in almost all sampled chicks. Nonetheless, in herring gull male chicks, total T3 levels were significantly and negatively associated with perfluorodecanoate (PFDA) and perfluorododecanoate (PFDoDA) and positively associated with perfluorotetradecanoate (PFTeDA) in female chicks. Total T3 levels were also positively associated with PFDoDA in great black backed gull male chicks and with perfluorotridecanoate (PFTrDA) in lesser black backed gull chicks. In lesser and great black-backed gulls, both females and males showed significant negative associations between several PFAS and their body condition, and a positive association between telomere length and L-PFOS in the yellow-legged gull was also found. These results corroborate previous findings and need to be further explored as they suggest that PFAS may interfere with the physiological ... Article in Journal/Newspaper Lesser black-backed gull IRUA - Institutional Repository van de Universiteit Antwerpen Science of The Total Environment 901 165920 |
institution |
Open Polar |
collection |
IRUA - Institutional Repository van de Universiteit Antwerpen |
op_collection_id |
ftunivantwerpen |
language |
English |
topic |
Chemistry Biology |
spellingShingle |
Chemistry Biology Sebastiano, Manrico Jouanneau, W. Blevin, P. Angelier, F. Pallud, M. Ribout, C. Gernigon, J. Lemesle, J.C. Robin, F. Pardon, P. Budzinski, H. Labadie, P. Chastel, O. Physiological effects of PFAS exposure in seabird chicks : a multi-species study of thyroid hormone triiodothyronine, body condition and telomere length in South Western France |
topic_facet |
Chemistry Biology |
description |
Abstract: There is growing evidence that poly and perfluoroalkyl substances (PFAS) exposure leads to the disruption of thyroid hormones including thyroxine (T4) and triiodothyronine (T3), and may affect telomeres, repetitive nucleotide sequences which protect chromosome ends. Many seabird species are long-lived top predators thus exhibit high contaminant levels, and PFAS-disrupting effects on their physiology have been documented especially in relation to the endocrine system in adults. On the contrary, studies on the developmental period (i.e., chicks), during which exposure to environmental contaminants may have a greater impact on physiological traits, remain scarce to this date. We carried out a multi-species study with the aim to assess whether and to which extent chicks of four gull species (herring gull, great and lesser black-backed gull, yellow-legged gull) in South Western France are contaminated by PFAS, and to bring further evidence about their potential physiological consequences. Linear PFOS showed concentrations of concern as it was generally >10 times higher than the other PFAS, and exceeded a threshold toxicity level (calculated from previous studies in birds) in almost all sampled chicks. Nonetheless, in herring gull male chicks, total T3 levels were significantly and negatively associated with perfluorodecanoate (PFDA) and perfluorododecanoate (PFDoDA) and positively associated with perfluorotetradecanoate (PFTeDA) in female chicks. Total T3 levels were also positively associated with PFDoDA in great black backed gull male chicks and with perfluorotridecanoate (PFTrDA) in lesser black backed gull chicks. In lesser and great black-backed gulls, both females and males showed significant negative associations between several PFAS and their body condition, and a positive association between telomere length and L-PFOS in the yellow-legged gull was also found. These results corroborate previous findings and need to be further explored as they suggest that PFAS may interfere with the physiological ... |
format |
Article in Journal/Newspaper |
author |
Sebastiano, Manrico Jouanneau, W. Blevin, P. Angelier, F. Pallud, M. Ribout, C. Gernigon, J. Lemesle, J.C. Robin, F. Pardon, P. Budzinski, H. Labadie, P. Chastel, O. |
author_facet |
Sebastiano, Manrico Jouanneau, W. Blevin, P. Angelier, F. Pallud, M. Ribout, C. Gernigon, J. Lemesle, J.C. Robin, F. Pardon, P. Budzinski, H. Labadie, P. Chastel, O. |
author_sort |
Sebastiano, Manrico |
title |
Physiological effects of PFAS exposure in seabird chicks : a multi-species study of thyroid hormone triiodothyronine, body condition and telomere length in South Western France |
title_short |
Physiological effects of PFAS exposure in seabird chicks : a multi-species study of thyroid hormone triiodothyronine, body condition and telomere length in South Western France |
title_full |
Physiological effects of PFAS exposure in seabird chicks : a multi-species study of thyroid hormone triiodothyronine, body condition and telomere length in South Western France |
title_fullStr |
Physiological effects of PFAS exposure in seabird chicks : a multi-species study of thyroid hormone triiodothyronine, body condition and telomere length in South Western France |
title_full_unstemmed |
Physiological effects of PFAS exposure in seabird chicks : a multi-species study of thyroid hormone triiodothyronine, body condition and telomere length in South Western France |
title_sort |
physiological effects of pfas exposure in seabird chicks : a multi-species study of thyroid hormone triiodothyronine, body condition and telomere length in south western france |
publishDate |
2023 |
url |
https://hdl.handle.net/10067/1992950151162165141 https://repository.uantwerpen.be/docstore/d:irua:19666 |
genre |
Lesser black-backed gull |
genre_facet |
Lesser black-backed gull |
op_source |
0048-9697 The science of the total environment |
op_relation |
info:eu-repo/semantics/altIdentifier/doi/10.1016/J.SCITOTENV.2023.165920 info:eu-repo/semantics/altIdentifier/isi/001066220700001 |
op_rights |
info:eu-repo/semantics/openAccess |
op_doi |
https://doi.org/10.1016/J.SCITOTENV.2023.165920 |
container_title |
Science of The Total Environment |
container_volume |
901 |
container_start_page |
165920 |
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1799483452770222080 |