Ocean acidification affects the expression of neuroplasticity and neuromodulation markers in seabream
A possible explanation for acidification-induced changes in fish behaviour is that acidification interferes with neurogenesis and modifies the plasticity of neuronal circuitry in the brain. We tested the effects on the olfactory system and brain of gilthead seabream (Sparus aurata) to 4 weeks'...
Published in: | Biology Open |
---|---|
Main Authors: | , , , |
Format: | Article in Journal/Newspaper |
Language: | English |
Published: |
Company Biologists LTD
2022
|
Subjects: | |
Online Access: | http://hdl.handle.net/10400.1/19261 https://doi.org/10.1242/bio.059073 |
id |
ftunivalgarve:oai:sapientia.ualg.pt:10400.1/19261 |
---|---|
record_format |
openpolar |
spelling |
ftunivalgarve:oai:sapientia.ualg.pt:10400.1/19261 2023-05-15T17:50:01+02:00 Ocean acidification affects the expression of neuroplasticity and neuromodulation markers in seabream A Costa, Rita Olvera, Aurora Power, Deborah Mary Velez, Zélia 2022-03 http://hdl.handle.net/10400.1/19261 https://doi.org/10.1242/bio.059073 eng eng Company Biologists LTD info:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDB%2F04326%2F2020/PT info:eu-repo/grantAgreement/FCT/9471 - RIDTI/PTDC%2FBIA-BMA%2F30262%2F2017/PT info:eu-repo/grantAgreement/FCT/OE/SFRH%2FBPD%2F100409%2F2014/PT 2046-6390 http://hdl.handle.net/10400.1/19261 doi:10.1242/bio.059073 openAccess http://creativecommons.org/licenses/by/4.0/ Ocean acidification Gilthead seabream Olfactory epithelium Thyroid hormones Neuroplasticity Neuromodulation article 2022 ftunivalgarve https://doi.org/10.1242/bio.059073 2023-03-22T01:04:44Z A possible explanation for acidification-induced changes in fish behaviour is that acidification interferes with neurogenesis and modifies the plasticity of neuronal circuitry in the brain. We tested the effects on the olfactory system and brain of gilthead seabream (Sparus aurata) to 4 weeks' exposure to ocean acidification (OA). Olfactory epithelium (OE) morphology changed shortly after OA exposure and persisted over the 4 weeks. Expression of genes related to olfactory transduction, neuronal excitability, synaptic plasticity, GABAergic innervation, and cell proliferation were unchanged in the OE and olfactory bulb (OB) after 4 weeks' exposure. Short-term changes in the ionic content of plasma and extradural fluid (EDF) returned to control levels after 4 weeks' exposure, except for [Cl-], which remained elevated. This suggests that, in general, there is an early physiological response to OA and by 4 weeks a new homeostatic status is achieved. However, expression of genes involved in proliferation, differentiation and survival of undifferentiated neurons were modified in the brain. In the same brain areas, expression of thyroid hormone signalling genes was altered suggesting modifications in the thyroid-system may be linked to the changes in neuroplasticity and neurogenesis. Overall, the results of the current study are consistent with and effect of OA on neuroplasticity. Mexican national funds from CONACYT -Consejo Nacional de Ciencia y Tecnologi'a, Mexico 2018-000022-01 info:eu-repo/semantics/publishedVersion Article in Journal/Newspaper Ocean acidification Universidade do Algarve: Sapienta Biology Open 11 3 |
institution |
Open Polar |
collection |
Universidade do Algarve: Sapienta |
op_collection_id |
ftunivalgarve |
language |
English |
topic |
Ocean acidification Gilthead seabream Olfactory epithelium Thyroid hormones Neuroplasticity Neuromodulation |
spellingShingle |
Ocean acidification Gilthead seabream Olfactory epithelium Thyroid hormones Neuroplasticity Neuromodulation A Costa, Rita Olvera, Aurora Power, Deborah Mary Velez, Zélia Ocean acidification affects the expression of neuroplasticity and neuromodulation markers in seabream |
topic_facet |
Ocean acidification Gilthead seabream Olfactory epithelium Thyroid hormones Neuroplasticity Neuromodulation |
description |
A possible explanation for acidification-induced changes in fish behaviour is that acidification interferes with neurogenesis and modifies the plasticity of neuronal circuitry in the brain. We tested the effects on the olfactory system and brain of gilthead seabream (Sparus aurata) to 4 weeks' exposure to ocean acidification (OA). Olfactory epithelium (OE) morphology changed shortly after OA exposure and persisted over the 4 weeks. Expression of genes related to olfactory transduction, neuronal excitability, synaptic plasticity, GABAergic innervation, and cell proliferation were unchanged in the OE and olfactory bulb (OB) after 4 weeks' exposure. Short-term changes in the ionic content of plasma and extradural fluid (EDF) returned to control levels after 4 weeks' exposure, except for [Cl-], which remained elevated. This suggests that, in general, there is an early physiological response to OA and by 4 weeks a new homeostatic status is achieved. However, expression of genes involved in proliferation, differentiation and survival of undifferentiated neurons were modified in the brain. In the same brain areas, expression of thyroid hormone signalling genes was altered suggesting modifications in the thyroid-system may be linked to the changes in neuroplasticity and neurogenesis. Overall, the results of the current study are consistent with and effect of OA on neuroplasticity. Mexican national funds from CONACYT -Consejo Nacional de Ciencia y Tecnologi'a, Mexico 2018-000022-01 info:eu-repo/semantics/publishedVersion |
format |
Article in Journal/Newspaper |
author |
A Costa, Rita Olvera, Aurora Power, Deborah Mary Velez, Zélia |
author_facet |
A Costa, Rita Olvera, Aurora Power, Deborah Mary Velez, Zélia |
author_sort |
A Costa, Rita |
title |
Ocean acidification affects the expression of neuroplasticity and neuromodulation markers in seabream |
title_short |
Ocean acidification affects the expression of neuroplasticity and neuromodulation markers in seabream |
title_full |
Ocean acidification affects the expression of neuroplasticity and neuromodulation markers in seabream |
title_fullStr |
Ocean acidification affects the expression of neuroplasticity and neuromodulation markers in seabream |
title_full_unstemmed |
Ocean acidification affects the expression of neuroplasticity and neuromodulation markers in seabream |
title_sort |
ocean acidification affects the expression of neuroplasticity and neuromodulation markers in seabream |
publisher |
Company Biologists LTD |
publishDate |
2022 |
url |
http://hdl.handle.net/10400.1/19261 https://doi.org/10.1242/bio.059073 |
genre |
Ocean acidification |
genre_facet |
Ocean acidification |
op_relation |
info:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDB%2F04326%2F2020/PT info:eu-repo/grantAgreement/FCT/9471 - RIDTI/PTDC%2FBIA-BMA%2F30262%2F2017/PT info:eu-repo/grantAgreement/FCT/OE/SFRH%2FBPD%2F100409%2F2014/PT 2046-6390 http://hdl.handle.net/10400.1/19261 doi:10.1242/bio.059073 |
op_rights |
openAccess http://creativecommons.org/licenses/by/4.0/ |
op_doi |
https://doi.org/10.1242/bio.059073 |
container_title |
Biology Open |
container_volume |
11 |
container_issue |
3 |
_version_ |
1766156579086794752 |