Is metal contamination responsible for increasing aneuploidy levels in the Manila clam Ruditapes philippinarum?
The present study assessed the metal genotoxicity potential at chromosome-level in the bivalve Ruditapes philippinarum collected along different areas of the Tagus estuary. Higher levels of aneuploidy on gill cells were detected at the most sediment contaminated area both in May (31.7%) and October...
Published in: | Science of The Total Environment |
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Format: | Article in Journal/Newspaper |
Language: | English |
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Elsevier Science Bv
2017
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Online Access: | http://hdl.handle.net/10400.1/13260 https://doi.org/10.1016/j.scitotenv.2016.10.193 |
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ftunivalgarve:oai:sapientia.ualg.pt:10400.1/13260 2023-05-15T15:59:00+02:00 Is metal contamination responsible for increasing aneuploidy levels in the Manila clam Ruditapes philippinarum? Piló, David Carvalho, S. Pereira, P. Gaspar, Miguel Leitao, A. 2017-01 http://hdl.handle.net/10400.1/13260 https://doi.org/10.1016/j.scitotenv.2016.10.193 eng eng Elsevier Science Bv info:eu-repo/grantAgreement/FCT/SFRH/SFRH%2FBPD%2F69563%2F2010/PT info:eu-repo/grantAgreement/FCT/3599-PPCDT/121037/PT 0048-9697 1879-1026 http://hdl.handle.net/10400.1/13260 doi:10.1016/j.scitotenv.2016.10.193 restrictedAccess Tagus estuary Portugal Salt-marsh areas Crassostrea-gigas Pacific oyster Heavy-metal Mercury contamination Hemocyte parameters Cerastoderma-edule Bivalve mollusks Coastal lagoons article 2017 ftunivalgarve https://doi.org/10.1016/j.scitotenv.2016.10.193 2022-05-30T08:48:54Z The present study assessed the metal genotoxicity potential at chromosome-level in the bivalve Ruditapes philippinarum collected along different areas of the Tagus estuary. Higher levels of aneuploidy on gill cells were detected at the most sediment contaminated area both in May (31.7%) and October (36.0%) when compared to a less contaminated area over the same periods (203% and 29.0% respectively). Interestingly, metal bioaccumulation in gills was higher in the specimens collected at the least contaminated area with the exception of Pb. Indeed, the multivariate analysis revealed a stronger relation between aneuploidy and sediment contamination than between aneuploidy and the bioaccumulation of the metals. The temporal and spatial inconsistency found for the bioaccumulation of metals in It philippinarum and the positive correlation between sediment contamination and aneuploidy at the most contaminated area suggest that these chromosome-level effects might be due to chronic metal contamination occurring in the Tagus estuary, rather than a direct result of the temporal variation of bioavailable contaminants. The vertical transmission phenomenon of bivalve aneuploidy levels may then be perpetuating those levels on clams from the most contaminated area. The present results shed light about the effect of metal toxicity at the chromosome-level in species inhabiting chronic contaminated areas and highlight the use of aneuploidy as an effective tool to identify persistent contamination in worldwide transitional waters. (C) 2016 Elsevier B.V. All rights reserved. Fundacao para a Ciencia e Tecnologia (FCT) project "ECOAPPROACH" [PTDC/AAC-AMB/121037/2010] FCT [SFRH/BPD/69563/2010] "Estrutura de Missao para a Extensao da Plataforma Continental" (EMEPC) Article in Journal/Newspaper Crassostrea gigas Pacific oyster Universidade do Algarve: Sapienta Pacific Science of The Total Environment 577 340 348 |
institution |
Open Polar |
collection |
Universidade do Algarve: Sapienta |
op_collection_id |
ftunivalgarve |
language |
English |
topic |
Tagus estuary Portugal Salt-marsh areas Crassostrea-gigas Pacific oyster Heavy-metal Mercury contamination Hemocyte parameters Cerastoderma-edule Bivalve mollusks Coastal lagoons |
spellingShingle |
Tagus estuary Portugal Salt-marsh areas Crassostrea-gigas Pacific oyster Heavy-metal Mercury contamination Hemocyte parameters Cerastoderma-edule Bivalve mollusks Coastal lagoons Piló, David Carvalho, S. Pereira, P. Gaspar, Miguel Leitao, A. Is metal contamination responsible for increasing aneuploidy levels in the Manila clam Ruditapes philippinarum? |
topic_facet |
Tagus estuary Portugal Salt-marsh areas Crassostrea-gigas Pacific oyster Heavy-metal Mercury contamination Hemocyte parameters Cerastoderma-edule Bivalve mollusks Coastal lagoons |
description |
The present study assessed the metal genotoxicity potential at chromosome-level in the bivalve Ruditapes philippinarum collected along different areas of the Tagus estuary. Higher levels of aneuploidy on gill cells were detected at the most sediment contaminated area both in May (31.7%) and October (36.0%) when compared to a less contaminated area over the same periods (203% and 29.0% respectively). Interestingly, metal bioaccumulation in gills was higher in the specimens collected at the least contaminated area with the exception of Pb. Indeed, the multivariate analysis revealed a stronger relation between aneuploidy and sediment contamination than between aneuploidy and the bioaccumulation of the metals. The temporal and spatial inconsistency found for the bioaccumulation of metals in It philippinarum and the positive correlation between sediment contamination and aneuploidy at the most contaminated area suggest that these chromosome-level effects might be due to chronic metal contamination occurring in the Tagus estuary, rather than a direct result of the temporal variation of bioavailable contaminants. The vertical transmission phenomenon of bivalve aneuploidy levels may then be perpetuating those levels on clams from the most contaminated area. The present results shed light about the effect of metal toxicity at the chromosome-level in species inhabiting chronic contaminated areas and highlight the use of aneuploidy as an effective tool to identify persistent contamination in worldwide transitional waters. (C) 2016 Elsevier B.V. All rights reserved. Fundacao para a Ciencia e Tecnologia (FCT) project "ECOAPPROACH" [PTDC/AAC-AMB/121037/2010] FCT [SFRH/BPD/69563/2010] "Estrutura de Missao para a Extensao da Plataforma Continental" (EMEPC) |
format |
Article in Journal/Newspaper |
author |
Piló, David Carvalho, S. Pereira, P. Gaspar, Miguel Leitao, A. |
author_facet |
Piló, David Carvalho, S. Pereira, P. Gaspar, Miguel Leitao, A. |
author_sort |
Piló, David |
title |
Is metal contamination responsible for increasing aneuploidy levels in the Manila clam Ruditapes philippinarum? |
title_short |
Is metal contamination responsible for increasing aneuploidy levels in the Manila clam Ruditapes philippinarum? |
title_full |
Is metal contamination responsible for increasing aneuploidy levels in the Manila clam Ruditapes philippinarum? |
title_fullStr |
Is metal contamination responsible for increasing aneuploidy levels in the Manila clam Ruditapes philippinarum? |
title_full_unstemmed |
Is metal contamination responsible for increasing aneuploidy levels in the Manila clam Ruditapes philippinarum? |
title_sort |
is metal contamination responsible for increasing aneuploidy levels in the manila clam ruditapes philippinarum? |
publisher |
Elsevier Science Bv |
publishDate |
2017 |
url |
http://hdl.handle.net/10400.1/13260 https://doi.org/10.1016/j.scitotenv.2016.10.193 |
geographic |
Pacific |
geographic_facet |
Pacific |
genre |
Crassostrea gigas Pacific oyster |
genre_facet |
Crassostrea gigas Pacific oyster |
op_relation |
info:eu-repo/grantAgreement/FCT/SFRH/SFRH%2FBPD%2F69563%2F2010/PT info:eu-repo/grantAgreement/FCT/3599-PPCDT/121037/PT 0048-9697 1879-1026 http://hdl.handle.net/10400.1/13260 doi:10.1016/j.scitotenv.2016.10.193 |
op_rights |
restrictedAccess |
op_doi |
https://doi.org/10.1016/j.scitotenv.2016.10.193 |
container_title |
Science of The Total Environment |
container_volume |
577 |
container_start_page |
340 |
op_container_end_page |
348 |
_version_ |
1766394785048821760 |