Speeding-up Enzyme-Catalyzed Synthesis of Polyamides using ω-Amino-α-Alkoxy-Acetate as Monomer

• Published in: Polymer
• Main Authors: Poulhès, Florent, Mouysset, Dominique, Gil, Gérard, Bertrand, Michèle. P., Gastaldi, Stéphane
• Other Authors: Institut de Chimie Radicalaire (ICR), Aix Marseille Université (AMU)-Institut de Chimie - CNRS Chimie (INC-CNRS)-Centre National de la Recherche Scientifique (CNRS), Institut des Sciences Moléculaires de Marseille (ISM2), Aix Marseille Université (AMU)-École Centrale de Marseille (ECM)-Institut de Chimie - CNRS Chimie (INC-CNRS)-Centre National de la Recherche Scientifique (CNRS)
• Format: Article in Journal/Newspaper
• Language: English
• Published: HAL CCSD 2013
• Subjects: polyamides; enzymes; monomers; [CHIM.ORGA]Chemical Sciences/Organic chemistry; Antarc*; Antarctica
• Online Access: https://amu.hal.science/hal-01408694; https://amu.hal.science/hal-01408694/document; https://amu.hal.science/hal-01408694/file/Polymer-Florent%202013-revised.pdf; https://doi.org/10.1016/j.polymer.2013.05.011

International audience The design of ω-amino-α-alkoxy-acetate as monomer enables to dramatically speed up the formation of polyamides catalyzed by the supported lipase B of Candida antarctica. Only 30 min are needed to reach 93% conversion whereas 240 h are necessary to observe the same level of conversion with a monomer devoided of an oxygen atom in position β relative to the electrophilic carbonyl group. Yields, Mn, Mw, DPn and PDI reach very good values for an enzymatic synthesis of polyamides.