Improving the Stability and Antioxidant Properties of Sesame Oil: Water-Soluble Spray-Dried Emulsions from New Transesterified Phenolic Derivatives

• Published in: Journal of Agricultural and Food Chemistry
• Main Authors: Alencar, Juliana, Gosset, Gaelle, Robin, Maxime, Pique, Valérie, Culcasi, Marcel, Mercier, Anne, Pietri, Sylvia
• Other Authors: Institut de Chimie Radicalaire (ICR), Aix Marseille Université (AMU)-Institut de Chimie - CNRS Chimie (INC-CNRS)-Centre National de la Recherche Scientifique (CNRS)
• Format: Article in Journal/Newspaper
• Language: English
• Published: HAL CCSD 2009
• Subjects: DEPMPO; 3T3 fibroblasts; UV irradiation; spray-dried emulsions; antioxidant capacity; ESR spin trapping; Sesame oil; enzymatic transesterification; vanillyl alcohol; [CHIM]Chemical Sciences; Antarc*; Antarctica
• Online Access: https://amu.hal.science/hal-01142289; https://doi.org/10.1021/jf9010627

International audience Hydrosoluble sesame oil fatty acid transesters having enhanced antioxidant activities were synthesizedin a two-step process. The key step involved the biocatalyzed (lipase from Candida antarctica)acylation of sesame oil methanolic ester with either vanillyl (VNA) or piperonyl benzylic alcohols, or5-hydroxymethyl resorcinol (5-HMR). These substrates were selected to introduce phenolic orsesamol structurally related frameworks. The VNA and 5-HMR-derived transesters were obtainedwith 20-40% yields and retained the starting proportions of sesame oil linoleic, oleic, and saturatedacids, these fatty acids also being the only constituents of the nonesterified fraction. The VNAderivedtransester showed the best antioxidant capacity in standard assays and was processed asthe unique lipid phase of spray-dried emulsions containing a high level of linoleic acid phenolic ester.These emulsions provided a high degree of protection to UV-irradiated fibroblasts, through thepotential synergy between VNA antioxidant action and replenishment of damaged membranes byunsaturated fatty acids.