Exploring lipid affinities of persistent organic pollutants and MeO-PBDEs in blubber of marine mammals
Although lipophilic compounds have been the focus of numerous studies in marine mammals, their association with lipids is widely accepted, but rarely scrutinized. This pilot study aimed to investigate potential relationships between individual lipids from different lipid classes identified through a...
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Online Access: | https://hdl.handle.net/2440/137132 https://doi.org/10.1016/j.chemosphere.2022.136448 |
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ftunivadelaidedl:oai:digital.library.adelaide.edu.au:2440/137132 2023-12-17T10:30:08+01:00 Exploring lipid affinities of persistent organic pollutants and MeO-PBDEs in blubber of marine mammals Weijs, L. Covaci, A. Carroll, A. Kemper, C. Melvin, S. 2022 https://hdl.handle.net/2440/137132 https://doi.org/10.1016/j.chemosphere.2022.136448 en eng Elsevier Ltd http://purl.org/au-research/grants/arc/DE160100468 Chemosphere, 2022; 308(Pt 3):136448- 0045-6535 1879-1298 https://hdl.handle.net/2440/137132 doi:10.1016/j.chemosphere.2022.136448 © 2022 Elsevier Ltd. All rights reserved. http://dx.doi.org/10.1016/j.chemosphere.2022.136448 Lipidomics Marine mammals Blubber Lipophilic POPs Adipose Tissue Animals Hexachlorobenzene Lipids Water Pollutants Chemical Pilot Projects Environmental Monitoring Fin Whale Sperm Whale Bottle-Nosed Dolphin Whales Pilot Halogenated Diphenyl Ethers Caniformia Persistent Organic Pollutants Journal article 2022 ftunivadelaidedl https://doi.org/10.1016/j.chemosphere.2022.136448 2023-11-20T23:29:46Z Although lipophilic compounds have been the focus of numerous studies in marine mammals, their association with lipids is widely accepted, but rarely scrutinized. This pilot study aimed to investigate potential relationships between individual lipids from different lipid classes identified through a non-targeted Nuclear Magnetic Resonance (NMR) based lipidomics approach and legacy POPs in the blubber of long-finned pilot whales, sperm whales, common bottlenose dolphins, and Indo-Pacific bottlenose dolphins. Concentrations of selected POPs such as HCB and HCHs in sperm whales from Tasmania were found to differ from those in long-finned pilot whales and common bottlenose dolphins from the same location. Profiles of NMR spectra measured in blubber of sperm whales were also distinctly different compared to the pilot whales and common bottlenose dolphins. Two groups of Indo-Pacific bottlenose dolphins from South Australia that were 20 years apart showed highly comparable profiles of NMR signals despite having higher concentrations of several POP classes in the more recent group. More specific correlations were investigated between selected POPs (n = 12) and all detected NMR signals (n = 63) in all species. Outcomes were species-specific, but difficult to interpret due to the lack of available literature for marine mammals and the small sample sizes per species. Because of the key role of lipids in the bioaccumulation of POPs and in the incidence of diseases, more attention should be given to the identification and characterization of lipid species in future toxicological studies. However, future studies should focus on one marine mammal species to increase sample sizes and limit the number of confounding factors, such as diet, that can influence POP and lipid levels and profiles. Liesbeth Weijs, Adrian Covaci, Anthony Carroll, Catherine Kemper, Steve Melvin Article in Journal/Newspaper Fin whale Sperm whale The University of Adelaide: Digital Library Pacific Chemosphere 308 136448 |
institution |
Open Polar |
collection |
The University of Adelaide: Digital Library |
op_collection_id |
ftunivadelaidedl |
language |
English |
topic |
Lipidomics Marine mammals Blubber Lipophilic POPs Adipose Tissue Animals Hexachlorobenzene Lipids Water Pollutants Chemical Pilot Projects Environmental Monitoring Fin Whale Sperm Whale Bottle-Nosed Dolphin Whales Pilot Halogenated Diphenyl Ethers Caniformia Persistent Organic Pollutants |
spellingShingle |
Lipidomics Marine mammals Blubber Lipophilic POPs Adipose Tissue Animals Hexachlorobenzene Lipids Water Pollutants Chemical Pilot Projects Environmental Monitoring Fin Whale Sperm Whale Bottle-Nosed Dolphin Whales Pilot Halogenated Diphenyl Ethers Caniformia Persistent Organic Pollutants Weijs, L. Covaci, A. Carroll, A. Kemper, C. Melvin, S. Exploring lipid affinities of persistent organic pollutants and MeO-PBDEs in blubber of marine mammals |
topic_facet |
Lipidomics Marine mammals Blubber Lipophilic POPs Adipose Tissue Animals Hexachlorobenzene Lipids Water Pollutants Chemical Pilot Projects Environmental Monitoring Fin Whale Sperm Whale Bottle-Nosed Dolphin Whales Pilot Halogenated Diphenyl Ethers Caniformia Persistent Organic Pollutants |
description |
Although lipophilic compounds have been the focus of numerous studies in marine mammals, their association with lipids is widely accepted, but rarely scrutinized. This pilot study aimed to investigate potential relationships between individual lipids from different lipid classes identified through a non-targeted Nuclear Magnetic Resonance (NMR) based lipidomics approach and legacy POPs in the blubber of long-finned pilot whales, sperm whales, common bottlenose dolphins, and Indo-Pacific bottlenose dolphins. Concentrations of selected POPs such as HCB and HCHs in sperm whales from Tasmania were found to differ from those in long-finned pilot whales and common bottlenose dolphins from the same location. Profiles of NMR spectra measured in blubber of sperm whales were also distinctly different compared to the pilot whales and common bottlenose dolphins. Two groups of Indo-Pacific bottlenose dolphins from South Australia that were 20 years apart showed highly comparable profiles of NMR signals despite having higher concentrations of several POP classes in the more recent group. More specific correlations were investigated between selected POPs (n = 12) and all detected NMR signals (n = 63) in all species. Outcomes were species-specific, but difficult to interpret due to the lack of available literature for marine mammals and the small sample sizes per species. Because of the key role of lipids in the bioaccumulation of POPs and in the incidence of diseases, more attention should be given to the identification and characterization of lipid species in future toxicological studies. However, future studies should focus on one marine mammal species to increase sample sizes and limit the number of confounding factors, such as diet, that can influence POP and lipid levels and profiles. Liesbeth Weijs, Adrian Covaci, Anthony Carroll, Catherine Kemper, Steve Melvin |
format |
Article in Journal/Newspaper |
author |
Weijs, L. Covaci, A. Carroll, A. Kemper, C. Melvin, S. |
author_facet |
Weijs, L. Covaci, A. Carroll, A. Kemper, C. Melvin, S. |
author_sort |
Weijs, L. |
title |
Exploring lipid affinities of persistent organic pollutants and MeO-PBDEs in blubber of marine mammals |
title_short |
Exploring lipid affinities of persistent organic pollutants and MeO-PBDEs in blubber of marine mammals |
title_full |
Exploring lipid affinities of persistent organic pollutants and MeO-PBDEs in blubber of marine mammals |
title_fullStr |
Exploring lipid affinities of persistent organic pollutants and MeO-PBDEs in blubber of marine mammals |
title_full_unstemmed |
Exploring lipid affinities of persistent organic pollutants and MeO-PBDEs in blubber of marine mammals |
title_sort |
exploring lipid affinities of persistent organic pollutants and meo-pbdes in blubber of marine mammals |
publisher |
Elsevier Ltd |
publishDate |
2022 |
url |
https://hdl.handle.net/2440/137132 https://doi.org/10.1016/j.chemosphere.2022.136448 |
geographic |
Pacific |
geographic_facet |
Pacific |
genre |
Fin whale Sperm whale |
genre_facet |
Fin whale Sperm whale |
op_source |
http://dx.doi.org/10.1016/j.chemosphere.2022.136448 |
op_relation |
http://purl.org/au-research/grants/arc/DE160100468 Chemosphere, 2022; 308(Pt 3):136448- 0045-6535 1879-1298 https://hdl.handle.net/2440/137132 doi:10.1016/j.chemosphere.2022.136448 |
op_rights |
© 2022 Elsevier Ltd. All rights reserved. |
op_doi |
https://doi.org/10.1016/j.chemosphere.2022.136448 |
container_title |
Chemosphere |
container_volume |
308 |
container_start_page |
136448 |
_version_ |
1785583041481015296 |