Dietary fatty acid source has little effect on the development of the immune system in the pyloric caeca of Atlantic salmon fry
The quality and relative amounts of dietary lipids may affect the health and growth of cultured Atlantic salmon. So far, little is known about their effects on the performance of the fish immune system during early life stages and, in particular their importance in the transition from endogenous nut...
Published in: | Scientific Reports |
---|---|
Main Authors: | , , , , , , , , , |
Format: | Article in Journal/Newspaper |
Language: | English |
Published: |
2019
|
Subjects: | |
Online Access: | http://hdl.handle.net/11368/2939560 https://doi.org/10.1038/s41598-018-37266-3 https://www.nature.com/articles/s41598-018-37266-3 |
id |
ftunitriestiris:oai:arts.units.it:11368/2939560 |
---|---|
record_format |
openpolar |
spelling |
ftunitriestiris:oai:arts.units.it:11368/2939560 2023-05-15T15:30:23+02:00 Dietary fatty acid source has little effect on the development of the immune system in the pyloric caeca of Atlantic salmon fry Jalili, Mahsa Jin, Yang Bones, Atle M. Olsen, Yngvar Vadstein, Olav Østensen, Mari-Ann Buonocore, Francesco Gerdol, Marco Pallavicini, Alberto Scapigliati, Giuseppe Jalili, Mahsa Jin, Yang Bones, Atle M. Olsen, Yngvar Vadstein, Olav Østensen, Mari-Ann Buonocore, Francesco Gerdol, Marco Pallavicini, Alberto Scapigliati, Giuseppe 2019 http://hdl.handle.net/11368/2939560 https://doi.org/10.1038/s41598-018-37266-3 https://www.nature.com/articles/s41598-018-37266-3 eng eng info:eu-repo/semantics/altIdentifier/pmid/30631091 info:eu-repo/semantics/altIdentifier/wos/WOS:000455352400010 volume:9 issue:1 firstpage:27 lastpage:27 numberofpages:1 journal:SCIENTIFIC REPORTS http://hdl.handle.net/11368/2939560 doi:10.1038/s41598-018-37266-3 info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85059828491 https://www.nature.com/articles/s41598-018-37266-3 info:eu-repo/semantics/openAccess Atlantic salmon mucosal immunity immunoglobulin complement system pyloric caeca info:eu-repo/semantics/article 2019 ftunitriestiris https://doi.org/10.1038/s41598-018-37266-3 2023-04-09T06:16:36Z The quality and relative amounts of dietary lipids may affect the health and growth of cultured Atlantic salmon. So far, little is known about their effects on the performance of the fish immune system during early life stages and, in particular their importance in the transition from endogenous nutrition (yolk) in the alevin stage to exogenous nutrition in the later fry stage. We investigated the immunomodulatory effects of fish oil, vegetable oil and phospholipid-rich oil in feeds for farmed Atlantic salmon using a transcriptomic approach. The experiment allowed a fine-scale monitoring of gene expression profiles in two tissues, the pyloric caeca of the intestine and the liver, in a 94 days-long first feeding experiment. The analysis of transcriptional profiles revealed that first feeding induced a strong immunomodulation in the pyloric caeca after 48 days of feeding, lasting up to day 94 and possibly beyond. On the other hand, the differential effect of the three dietary regimes was negligible. We interpret this upregulation, undetectable in liver, as a potentiation of the immune system upon the first contact of the digestive system with exogenous feed. This process involved a complex network of gene products involved in both cellular and humoral immunity. We identified the classical pathway of the complement system, acting at the crossroads between innate and adaptive immunity, as a key process modulated in response to the switch from endogenous to exogenous nutrition. Article in Journal/Newspaper Atlantic salmon Università degli studi di Trieste: ArTS (Archivio della ricerca di Trieste) Scientific Reports 9 1 |
institution |
Open Polar |
collection |
Università degli studi di Trieste: ArTS (Archivio della ricerca di Trieste) |
op_collection_id |
ftunitriestiris |
language |
English |
topic |
Atlantic salmon mucosal immunity immunoglobulin complement system pyloric caeca |
spellingShingle |
Atlantic salmon mucosal immunity immunoglobulin complement system pyloric caeca Jalili, Mahsa Jin, Yang Bones, Atle M. Olsen, Yngvar Vadstein, Olav Østensen, Mari-Ann Buonocore, Francesco Gerdol, Marco Pallavicini, Alberto Scapigliati, Giuseppe Dietary fatty acid source has little effect on the development of the immune system in the pyloric caeca of Atlantic salmon fry |
topic_facet |
Atlantic salmon mucosal immunity immunoglobulin complement system pyloric caeca |
description |
The quality and relative amounts of dietary lipids may affect the health and growth of cultured Atlantic salmon. So far, little is known about their effects on the performance of the fish immune system during early life stages and, in particular their importance in the transition from endogenous nutrition (yolk) in the alevin stage to exogenous nutrition in the later fry stage. We investigated the immunomodulatory effects of fish oil, vegetable oil and phospholipid-rich oil in feeds for farmed Atlantic salmon using a transcriptomic approach. The experiment allowed a fine-scale monitoring of gene expression profiles in two tissues, the pyloric caeca of the intestine and the liver, in a 94 days-long first feeding experiment. The analysis of transcriptional profiles revealed that first feeding induced a strong immunomodulation in the pyloric caeca after 48 days of feeding, lasting up to day 94 and possibly beyond. On the other hand, the differential effect of the three dietary regimes was negligible. We interpret this upregulation, undetectable in liver, as a potentiation of the immune system upon the first contact of the digestive system with exogenous feed. This process involved a complex network of gene products involved in both cellular and humoral immunity. We identified the classical pathway of the complement system, acting at the crossroads between innate and adaptive immunity, as a key process modulated in response to the switch from endogenous to exogenous nutrition. |
author2 |
Jalili, Mahsa Jin, Yang Bones, Atle M. Olsen, Yngvar Vadstein, Olav Østensen, Mari-Ann Buonocore, Francesco Gerdol, Marco Pallavicini, Alberto Scapigliati, Giuseppe |
format |
Article in Journal/Newspaper |
author |
Jalili, Mahsa Jin, Yang Bones, Atle M. Olsen, Yngvar Vadstein, Olav Østensen, Mari-Ann Buonocore, Francesco Gerdol, Marco Pallavicini, Alberto Scapigliati, Giuseppe |
author_facet |
Jalili, Mahsa Jin, Yang Bones, Atle M. Olsen, Yngvar Vadstein, Olav Østensen, Mari-Ann Buonocore, Francesco Gerdol, Marco Pallavicini, Alberto Scapigliati, Giuseppe |
author_sort |
Jalili, Mahsa |
title |
Dietary fatty acid source has little effect on the development of the immune system in the pyloric caeca of Atlantic salmon fry |
title_short |
Dietary fatty acid source has little effect on the development of the immune system in the pyloric caeca of Atlantic salmon fry |
title_full |
Dietary fatty acid source has little effect on the development of the immune system in the pyloric caeca of Atlantic salmon fry |
title_fullStr |
Dietary fatty acid source has little effect on the development of the immune system in the pyloric caeca of Atlantic salmon fry |
title_full_unstemmed |
Dietary fatty acid source has little effect on the development of the immune system in the pyloric caeca of Atlantic salmon fry |
title_sort |
dietary fatty acid source has little effect on the development of the immune system in the pyloric caeca of atlantic salmon fry |
publishDate |
2019 |
url |
http://hdl.handle.net/11368/2939560 https://doi.org/10.1038/s41598-018-37266-3 https://www.nature.com/articles/s41598-018-37266-3 |
genre |
Atlantic salmon |
genre_facet |
Atlantic salmon |
op_relation |
info:eu-repo/semantics/altIdentifier/pmid/30631091 info:eu-repo/semantics/altIdentifier/wos/WOS:000455352400010 volume:9 issue:1 firstpage:27 lastpage:27 numberofpages:1 journal:SCIENTIFIC REPORTS http://hdl.handle.net/11368/2939560 doi:10.1038/s41598-018-37266-3 info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85059828491 https://www.nature.com/articles/s41598-018-37266-3 |
op_rights |
info:eu-repo/semantics/openAccess |
op_doi |
https://doi.org/10.1038/s41598-018-37266-3 |
container_title |
Scientific Reports |
container_volume |
9 |
container_issue |
1 |
_version_ |
1766360839512653824 |