Impact of diabetes on maternal-fetal outcomes in Manitoba: Relationship with ethnic and environmental factors

Purpose: To examine the impact of gestational diabetes mellitus (GDM) on maternal-fetal outcomes in Manitoba. Methods: The rates of macrosomia, stillbirth, cesarean section (C/S) and shoulder dystocia (S/D) in 324,605 births in Manitoba during 1985-2004, and their relationships with diabetes and dem...

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Bibliographic Details
Published in:Clinical & Investigative Medicine
Main Authors: Aljohani, Naji, Rempel, Brenda M, Ludwig, Sora, Morris, Margaret, Cheang, Mary, Murray, Robert, Bruce, Sharon, Shen, Garry X
Format: Article in Journal/Newspaper
Language:English
Published: Canadian Society for Clinical Investigation 2008
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Online Access:https://cimonline.ca/index.php/cim/article/view/4919
https://doi.org/10.25011/cim.v31i6.4919
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Summary:Purpose: To examine the impact of gestational diabetes mellitus (GDM) on maternal-fetal outcomes in Manitoba. Methods: The rates of macrosomia, stillbirth, cesarean section (C/S) and shoulder dystocia (S/D) in 324,605 births in Manitoba during 1985-2004, and their relationships with diabetes and demographical factors were analyzed. Results: The incidence of macrosomia, stillbirth, C/S and S/D were 15.3%, 0.57%, 16.0%, and 1.2%, respectively. The rates of macrosomia were elevated in mothers with GDM, type 2 DM (T2DM), rural living, First Nations (FN) status, or ?35 years of age. Increased rates of stillbirth were associated with women with T2DM, FN status or ?35 years, but not those with GDM. C/S and S/D were increased in women with GDM or T2DM. FN status in combination with GDM increased the risk of S/D. Conclusions: GDM, T2DM, advanced maternal age, FN status or rural living affected pregnancy outcomes in Manitoba.