Spirometry is not enough to diagnose COPD in epidemiological studies: a follow-up study.

A hallmark of the diagnosis of chronic obstructive pulmonary disease (COPD) is the measurement of post-bronchodilator (post-BD) airflow obstruction (AO) by spirometry, but spirometry is not enough for the provision of a clinical diagnosis. In the majority of previous epidemiological studies, COPD di...

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Published in:npj Primary Care Respiratory Medicine
Main Authors: Andreeva, Elena, Pokhaznikova, Marina, Lebedev, Anatoly, Moiseeva, Irina, Kuznetsova, Olga, Degryse, Jean-Marie
Other Authors: UCL - SSS/IRSS - Institut de recherche santé et société, UCL - SSH/IACS - Institute of Analysis of Change in Contemporary and Historical Societies
Format: Article in Journal/Newspaper
Language:English
Published: Nature Publishing Group 2017
Subjects:
Online Access:http://hdl.handle.net/2078.1/189886
https://doi.org/10.1038/s41533-017-0062-6
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spelling ftunistlouisbrus:oai:dial.uclouvain.be:boreal:189886 2024-05-12T08:08:39+00:00 Spirometry is not enough to diagnose COPD in epidemiological studies: a follow-up study. Andreeva, Elena Pokhaznikova, Marina Lebedev, Anatoly Moiseeva, Irina Kuznetsova, Olga Degryse, Jean-Marie UCL - SSS/IRSS - Institut de recherche santé et société UCL - SSH/IACS - Institute of Analysis of Change in Contemporary and Historical Societies 2017 http://hdl.handle.net/2078.1/189886 https://doi.org/10.1038/s41533-017-0062-6 eng eng Nature Publishing Group boreal:189886 http://hdl.handle.net/2078.1/189886 doi:10.1038/s41533-017-0062-6 info:pmid/29138407 urn:EISSN:2055-1010 info:eu-repo/semantics/openAccess N P J Primary Care Respiratory Medicine, Vol. 27, no. 1, p. 62 [1-9] (2017) IRSS info:eu-repo/semantics/article 2017 ftunistlouisbrus https://doi.org/10.1038/s41533-017-0062-6 2024-04-18T17:34:18Z A hallmark of the diagnosis of chronic obstructive pulmonary disease (COPD) is the measurement of post-bronchodilator (post-BD) airflow obstruction (AO) by spirometry, but spirometry is not enough for the provision of a clinical diagnosis. In the majority of previous epidemiological studies, COPD diagnosis has been based on spirometry and a few clinical characteristics. The aim of our study was to identify outcomes in patients newly diagnosed with airflow obstruction (AO) based on a diagnostic work-up conducted as part of a population-based cross-sectional study in North-Western Russia. Spirometry was performed before (pre-BD) and after BD administration, and AO was defined using the FEV1/FVC <0.70 and FEV1/FVC <lower limit of normal cut-off values. Relevant symptoms were recorded. Participants with AO identified at baseline were then examined by a pulmonologist, including a clinical examination and second spirometry with BD test. Of the 102 participants with post-BD AO in the initial assessment, only 60.8% still had AO identified at the second examination; among these patients, the following final diagnoses were reported: COPD (n = 41), asthma (n = 5), asthma-COPD overlap syndrome (ACOS) (n = 4) and likely ACOS (n = 5). Of the 65 participants with pre-BD AO, 23.1% had post-BD AO at the second assessment, and these patients had been diagnosed with COPD (n = 12), asthma (n = 1), ACOS (n = 1), likely ACOS (n = 1). Serial spirometric assessments complemented by a comprehensive clinical evaluation are recommended in new epidemiological studies. Article in Journal/Newspaper North-Western Russia DIAL@USL-B (Université Saint-Louis, Bruxelles) npj Primary Care Respiratory Medicine 27 1
institution Open Polar
collection DIAL@USL-B (Université Saint-Louis, Bruxelles)
op_collection_id ftunistlouisbrus
language English
topic IRSS
spellingShingle IRSS
Andreeva, Elena
Pokhaznikova, Marina
Lebedev, Anatoly
Moiseeva, Irina
Kuznetsova, Olga
Degryse, Jean-Marie
Spirometry is not enough to diagnose COPD in epidemiological studies: a follow-up study.
topic_facet IRSS
description A hallmark of the diagnosis of chronic obstructive pulmonary disease (COPD) is the measurement of post-bronchodilator (post-BD) airflow obstruction (AO) by spirometry, but spirometry is not enough for the provision of a clinical diagnosis. In the majority of previous epidemiological studies, COPD diagnosis has been based on spirometry and a few clinical characteristics. The aim of our study was to identify outcomes in patients newly diagnosed with airflow obstruction (AO) based on a diagnostic work-up conducted as part of a population-based cross-sectional study in North-Western Russia. Spirometry was performed before (pre-BD) and after BD administration, and AO was defined using the FEV1/FVC <0.70 and FEV1/FVC <lower limit of normal cut-off values. Relevant symptoms were recorded. Participants with AO identified at baseline were then examined by a pulmonologist, including a clinical examination and second spirometry with BD test. Of the 102 participants with post-BD AO in the initial assessment, only 60.8% still had AO identified at the second examination; among these patients, the following final diagnoses were reported: COPD (n = 41), asthma (n = 5), asthma-COPD overlap syndrome (ACOS) (n = 4) and likely ACOS (n = 5). Of the 65 participants with pre-BD AO, 23.1% had post-BD AO at the second assessment, and these patients had been diagnosed with COPD (n = 12), asthma (n = 1), ACOS (n = 1), likely ACOS (n = 1). Serial spirometric assessments complemented by a comprehensive clinical evaluation are recommended in new epidemiological studies.
author2 UCL - SSS/IRSS - Institut de recherche santé et société
UCL - SSH/IACS - Institute of Analysis of Change in Contemporary and Historical Societies
format Article in Journal/Newspaper
author Andreeva, Elena
Pokhaznikova, Marina
Lebedev, Anatoly
Moiseeva, Irina
Kuznetsova, Olga
Degryse, Jean-Marie
author_facet Andreeva, Elena
Pokhaznikova, Marina
Lebedev, Anatoly
Moiseeva, Irina
Kuznetsova, Olga
Degryse, Jean-Marie
author_sort Andreeva, Elena
title Spirometry is not enough to diagnose COPD in epidemiological studies: a follow-up study.
title_short Spirometry is not enough to diagnose COPD in epidemiological studies: a follow-up study.
title_full Spirometry is not enough to diagnose COPD in epidemiological studies: a follow-up study.
title_fullStr Spirometry is not enough to diagnose COPD in epidemiological studies: a follow-up study.
title_full_unstemmed Spirometry is not enough to diagnose COPD in epidemiological studies: a follow-up study.
title_sort spirometry is not enough to diagnose copd in epidemiological studies: a follow-up study.
publisher Nature Publishing Group
publishDate 2017
url http://hdl.handle.net/2078.1/189886
https://doi.org/10.1038/s41533-017-0062-6
genre North-Western Russia
genre_facet North-Western Russia
op_source N P J Primary Care Respiratory Medicine, Vol. 27, no. 1, p. 62 [1-9] (2017)
op_relation boreal:189886
http://hdl.handle.net/2078.1/189886
doi:10.1038/s41533-017-0062-6
info:pmid/29138407
urn:EISSN:2055-1010
op_rights info:eu-repo/semantics/openAccess
op_doi https://doi.org/10.1038/s41533-017-0062-6
container_title npj Primary Care Respiratory Medicine
container_volume 27
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