Production and characterization of a cement (CEMP1) recombining protein in Drosophila melanogaster (DML-2-23) cells
To the present date, molecular and cellular factors which regulate cement formation and mineralization processes are not well known. This is mainly due to the lack of a biological marker for this type of tissue. We have recently isolated, cloned and expressed a protein derived from human radicular (...
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ftuninamexicoojs:oai:ojs.pkp.sfu.ca:article/69712 2023-05-15T16:01:54+02:00 Production and characterization of a cement (CEMP1) recombining protein in Drosophila melanogaster (DML-2-23) cells Rivera Priego, Adriana Carmona Rodriguez, Bruno Arzate, Higinio 2019-05-17 application/pdf https://www.journals.unam.mx/index.php/rom/article/view/69712 spa spa Facultad de Odontología https://www.journals.unam.mx/index.php/rom/article/view/69712/61531 https://www.journals.unam.mx/index.php/rom/article/view/69712 Derechos de autor 2019 Universidad Nacional Autónoma de México Revista Odontológica Mexicana; Vol. 17 No. 2 (2013): Versión Inglés Revista Odontológica Mexicana; Vol. 17 Núm. 2 (2013): Versión Inglés 1870-199X Cementum CEMP1 cementogenesis periodontal regeneration info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion 2019 ftuninamexicoojs 2022-12-27T21:29:21Z To the present date, molecular and cellular factors which regulate cement formation and mineralization processes are not well known. This is mainly due to the lack of a biological marker for this type of tissue. We have recently isolated, cloned and expressed a protein derived from human radicular (root) cement, called cement protein. This protein is expressed by cementoblasts as well as periodontium progenitor cells. The aim of the present work was to express cement protein in Drosophila melanogaster cells, so as to determine, in the future, its post-translational modifi cations. Our results show we have established a cellular line which expresses protein cement in an essential and stable fashion. This fact is of unique importance, since in the mediate future these cells will become the vehicle for cement protein production in suffi cient amounts to determine in a predictable manner, its role during the process of de novo periodontium formation process in animal models. Article in Journal/Newspaper DML Revistas UNAM (Universidad Nacional Autónoma de México) |
institution |
Open Polar |
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Revistas UNAM (Universidad Nacional Autónoma de México) |
op_collection_id |
ftuninamexicoojs |
language |
Spanish |
topic |
Cementum CEMP1 cementogenesis periodontal regeneration |
spellingShingle |
Cementum CEMP1 cementogenesis periodontal regeneration Rivera Priego, Adriana Carmona Rodriguez, Bruno Arzate, Higinio Production and characterization of a cement (CEMP1) recombining protein in Drosophila melanogaster (DML-2-23) cells |
topic_facet |
Cementum CEMP1 cementogenesis periodontal regeneration |
description |
To the present date, molecular and cellular factors which regulate cement formation and mineralization processes are not well known. This is mainly due to the lack of a biological marker for this type of tissue. We have recently isolated, cloned and expressed a protein derived from human radicular (root) cement, called cement protein. This protein is expressed by cementoblasts as well as periodontium progenitor cells. The aim of the present work was to express cement protein in Drosophila melanogaster cells, so as to determine, in the future, its post-translational modifi cations. Our results show we have established a cellular line which expresses protein cement in an essential and stable fashion. This fact is of unique importance, since in the mediate future these cells will become the vehicle for cement protein production in suffi cient amounts to determine in a predictable manner, its role during the process of de novo periodontium formation process in animal models. |
format |
Article in Journal/Newspaper |
author |
Rivera Priego, Adriana Carmona Rodriguez, Bruno Arzate, Higinio |
author_facet |
Rivera Priego, Adriana Carmona Rodriguez, Bruno Arzate, Higinio |
author_sort |
Rivera Priego, Adriana |
title |
Production and characterization of a cement (CEMP1) recombining protein in Drosophila melanogaster (DML-2-23) cells |
title_short |
Production and characterization of a cement (CEMP1) recombining protein in Drosophila melanogaster (DML-2-23) cells |
title_full |
Production and characterization of a cement (CEMP1) recombining protein in Drosophila melanogaster (DML-2-23) cells |
title_fullStr |
Production and characterization of a cement (CEMP1) recombining protein in Drosophila melanogaster (DML-2-23) cells |
title_full_unstemmed |
Production and characterization of a cement (CEMP1) recombining protein in Drosophila melanogaster (DML-2-23) cells |
title_sort |
production and characterization of a cement (cemp1) recombining protein in drosophila melanogaster (dml-2-23) cells |
publisher |
Facultad de Odontología |
publishDate |
2019 |
url |
https://www.journals.unam.mx/index.php/rom/article/view/69712 |
genre |
DML |
genre_facet |
DML |
op_source |
Revista Odontológica Mexicana; Vol. 17 No. 2 (2013): Versión Inglés Revista Odontológica Mexicana; Vol. 17 Núm. 2 (2013): Versión Inglés 1870-199X |
op_relation |
https://www.journals.unam.mx/index.php/rom/article/view/69712/61531 https://www.journals.unam.mx/index.php/rom/article/view/69712 |
op_rights |
Derechos de autor 2019 Universidad Nacional Autónoma de México |
_version_ |
1766397584511860736 |