Transgenerational plasticity and antiviral immunity in the Pacific oyster (Crassostrea gigas) against Ostreid herpesvirus 1 (OsHV-1)
International audience The oyster's immune system is capable of adapting upon exposure to a pathogen-associated molecular pattern (PAMP) to have an enhanced secondary response against the same type of pathogen. This has been demonstrated using poly(I:C) to elicit an antiviral response in the Pa...
Published in: | Developmental & Comparative Immunology |
---|---|
Main Authors: | , , , , , |
Other Authors: | , , , , , , |
Format: | Article in Journal/Newspaper |
Language: | English |
Published: |
HAL CCSD
2019
|
Subjects: | |
Online Access: | https://hal.science/hal-01904719 https://hal.science/hal-01904719/document https://hal.science/hal-01904719/file/Lafont-2019-DevComIm-Transgenerational-MANUSCRIT.pdf https://doi.org/10.1016/j.dci.2018.09.022 |
id |
ftunimontpellier:oai:HAL:hal-01904719v1 |
---|---|
record_format |
openpolar |
spelling |
ftunimontpellier:oai:HAL:hal-01904719v1 2024-02-11T10:03:02+01:00 Transgenerational plasticity and antiviral immunity in the Pacific oyster (Crassostrea gigas) against Ostreid herpesvirus 1 (OsHV-1) Lafont, Maxime Goncalves, Priscila Guo, Ximing Montagnani, Caroline Raftos, David Green, Timothy Interactions Hôtes-Pathogènes-Environnements (IHPE) Université de Perpignan Via Domitia (UPVD)-Institut Français de Recherche pour l'Exploitation de la Mer (IFREMER)-Centre National de la Recherche Scientifique (CNRS)-Université de Montpellier (UM) Sydney Institute of Marine Science Macquarie University Sydney Haskin Shellfish Research Laboratory (HSRL) Rutgers, The State University of New Jersey New Brunswick (RU) Rutgers University System (Rutgers)-Rutgers University System (Rutgers) 2019 https://hal.science/hal-01904719 https://hal.science/hal-01904719/document https://hal.science/hal-01904719/file/Lafont-2019-DevComIm-Transgenerational-MANUSCRIT.pdf https://doi.org/10.1016/j.dci.2018.09.022 en eng HAL CCSD Elsevier info:eu-repo/semantics/altIdentifier/doi/10.1016/j.dci.2018.09.022 hal-01904719 https://hal.science/hal-01904719 https://hal.science/hal-01904719/document https://hal.science/hal-01904719/file/Lafont-2019-DevComIm-Transgenerational-MANUSCRIT.pdf doi:10.1016/j.dci.2018.09.022 info:eu-repo/semantics/OpenAccess ISSN: 0145-305X Developmental and Comparative Immunology https://hal.science/hal-01904719 Developmental and Comparative Immunology, 2019, 91, pp.17 - 25. ⟨10.1016/j.dci.2018.09.022⟩ Crassostrea gigas OsHV-1 Transgenerational immune priming Trained immunity RNA-seq [SDV.IMM.II]Life Sciences [q-bio]/Immunology/Innate immunity [SDV.IMM.IA]Life Sciences [q-bio]/Immunology/Adaptive immunology [SDV.BA.ZI]Life Sciences [q-bio]/Animal biology/Invertebrate Zoology info:eu-repo/semantics/article Journal articles 2019 ftunimontpellier https://doi.org/10.1016/j.dci.2018.09.022 2024-01-23T23:39:51Z International audience The oyster's immune system is capable of adapting upon exposure to a pathogen-associated molecular pattern (PAMP) to have an enhanced secondary response against the same type of pathogen. This has been demonstrated using poly(I:C) to elicit an antiviral response in the Pacific oyster (Crassostrea gigas) against Ostreid herpesvirus (OsHV-1). Improved survival following exposure to poly(I:C) has been found in later life stages (within-generational immune priming) and in the next generation (transgenerational immune priming). The mechanism that the oyster uses to transfer immunity to the next generation is unknown. Here we show that oyster larvae have higher survival to OsHV-1 when their mothers, but not their fathers, are exposed to poly(I:C) prior to spawning. RNA-seq provided no evidence to suggest that parental exposure to poly(I:C) reconfigures antiviral gene expression in unchallenged larvae. We conclude that the improved survival of larvae might occur via maternal provisioning of antiviral compounds in the eggs. Article in Journal/Newspaper Crassostrea gigas Pacific oyster Université de Montpellier: HAL Pacific Developmental & Comparative Immunology 91 17 25 |
institution |
Open Polar |
collection |
Université de Montpellier: HAL |
op_collection_id |
ftunimontpellier |
language |
English |
topic |
Crassostrea gigas OsHV-1 Transgenerational immune priming Trained immunity RNA-seq [SDV.IMM.II]Life Sciences [q-bio]/Immunology/Innate immunity [SDV.IMM.IA]Life Sciences [q-bio]/Immunology/Adaptive immunology [SDV.BA.ZI]Life Sciences [q-bio]/Animal biology/Invertebrate Zoology |
spellingShingle |
Crassostrea gigas OsHV-1 Transgenerational immune priming Trained immunity RNA-seq [SDV.IMM.II]Life Sciences [q-bio]/Immunology/Innate immunity [SDV.IMM.IA]Life Sciences [q-bio]/Immunology/Adaptive immunology [SDV.BA.ZI]Life Sciences [q-bio]/Animal biology/Invertebrate Zoology Lafont, Maxime Goncalves, Priscila Guo, Ximing Montagnani, Caroline Raftos, David Green, Timothy Transgenerational plasticity and antiviral immunity in the Pacific oyster (Crassostrea gigas) against Ostreid herpesvirus 1 (OsHV-1) |
topic_facet |
Crassostrea gigas OsHV-1 Transgenerational immune priming Trained immunity RNA-seq [SDV.IMM.II]Life Sciences [q-bio]/Immunology/Innate immunity [SDV.IMM.IA]Life Sciences [q-bio]/Immunology/Adaptive immunology [SDV.BA.ZI]Life Sciences [q-bio]/Animal biology/Invertebrate Zoology |
description |
International audience The oyster's immune system is capable of adapting upon exposure to a pathogen-associated molecular pattern (PAMP) to have an enhanced secondary response against the same type of pathogen. This has been demonstrated using poly(I:C) to elicit an antiviral response in the Pacific oyster (Crassostrea gigas) against Ostreid herpesvirus (OsHV-1). Improved survival following exposure to poly(I:C) has been found in later life stages (within-generational immune priming) and in the next generation (transgenerational immune priming). The mechanism that the oyster uses to transfer immunity to the next generation is unknown. Here we show that oyster larvae have higher survival to OsHV-1 when their mothers, but not their fathers, are exposed to poly(I:C) prior to spawning. RNA-seq provided no evidence to suggest that parental exposure to poly(I:C) reconfigures antiviral gene expression in unchallenged larvae. We conclude that the improved survival of larvae might occur via maternal provisioning of antiviral compounds in the eggs. |
author2 |
Interactions Hôtes-Pathogènes-Environnements (IHPE) Université de Perpignan Via Domitia (UPVD)-Institut Français de Recherche pour l'Exploitation de la Mer (IFREMER)-Centre National de la Recherche Scientifique (CNRS)-Université de Montpellier (UM) Sydney Institute of Marine Science Macquarie University Sydney Haskin Shellfish Research Laboratory (HSRL) Rutgers, The State University of New Jersey New Brunswick (RU) Rutgers University System (Rutgers)-Rutgers University System (Rutgers) |
format |
Article in Journal/Newspaper |
author |
Lafont, Maxime Goncalves, Priscila Guo, Ximing Montagnani, Caroline Raftos, David Green, Timothy |
author_facet |
Lafont, Maxime Goncalves, Priscila Guo, Ximing Montagnani, Caroline Raftos, David Green, Timothy |
author_sort |
Lafont, Maxime |
title |
Transgenerational plasticity and antiviral immunity in the Pacific oyster (Crassostrea gigas) against Ostreid herpesvirus 1 (OsHV-1) |
title_short |
Transgenerational plasticity and antiviral immunity in the Pacific oyster (Crassostrea gigas) against Ostreid herpesvirus 1 (OsHV-1) |
title_full |
Transgenerational plasticity and antiviral immunity in the Pacific oyster (Crassostrea gigas) against Ostreid herpesvirus 1 (OsHV-1) |
title_fullStr |
Transgenerational plasticity and antiviral immunity in the Pacific oyster (Crassostrea gigas) against Ostreid herpesvirus 1 (OsHV-1) |
title_full_unstemmed |
Transgenerational plasticity and antiviral immunity in the Pacific oyster (Crassostrea gigas) against Ostreid herpesvirus 1 (OsHV-1) |
title_sort |
transgenerational plasticity and antiviral immunity in the pacific oyster (crassostrea gigas) against ostreid herpesvirus 1 (oshv-1) |
publisher |
HAL CCSD |
publishDate |
2019 |
url |
https://hal.science/hal-01904719 https://hal.science/hal-01904719/document https://hal.science/hal-01904719/file/Lafont-2019-DevComIm-Transgenerational-MANUSCRIT.pdf https://doi.org/10.1016/j.dci.2018.09.022 |
geographic |
Pacific |
geographic_facet |
Pacific |
genre |
Crassostrea gigas Pacific oyster |
genre_facet |
Crassostrea gigas Pacific oyster |
op_source |
ISSN: 0145-305X Developmental and Comparative Immunology https://hal.science/hal-01904719 Developmental and Comparative Immunology, 2019, 91, pp.17 - 25. ⟨10.1016/j.dci.2018.09.022⟩ |
op_relation |
info:eu-repo/semantics/altIdentifier/doi/10.1016/j.dci.2018.09.022 hal-01904719 https://hal.science/hal-01904719 https://hal.science/hal-01904719/document https://hal.science/hal-01904719/file/Lafont-2019-DevComIm-Transgenerational-MANUSCRIT.pdf doi:10.1016/j.dci.2018.09.022 |
op_rights |
info:eu-repo/semantics/OpenAccess |
op_doi |
https://doi.org/10.1016/j.dci.2018.09.022 |
container_title |
Developmental & Comparative Immunology |
container_volume |
91 |
container_start_page |
17 |
op_container_end_page |
25 |
_version_ |
1790599164201009152 |