Gastro-protective effect of capsaicin in Anguilla anguilla (Linneus, 1758): evidence from an experimental study on gastric bags.
An experimental, macroscopical, study was undertaken in european eel (Anguilla anguilla) to assess the gastro-protective effect of capsaicin, the active component contained in pepper. Gastric bags were prepared from specimens of Anguilla anguilla and used for in vitro study of the ability of capsaic...
Main Authors: | , , |
---|---|
Other Authors: | , , |
Format: | Article in Journal/Newspaper |
Language: | English |
Published: |
2006
|
Subjects: | |
Online Access: | http://hdl.handle.net/11570/1889770 |
id |
ftunimessinairis:oai:iris.unime.it:11570/1889770 |
---|---|
record_format |
openpolar |
spelling |
ftunimessinairis:oai:iris.unime.it:11570/1889770 2024-02-04T09:52:52+01:00 Gastro-protective effect of capsaicin in Anguilla anguilla (Linneus, 1758): evidence from an experimental study on gastric bags. DENARO, Maria Gabr. CARUSO G GENOVESE L. Denaro, Maria Gabr. Caruso, G Genovese, L. 2006 http://hdl.handle.net/11570/1889770 eng eng volume:3 (3) firstpage:263 lastpage:271 numberofpages:9 journal:ITTIOPATOLOGIA http://hdl.handle.net/11570/1889770 Anguilla anguilla Gastric ulcer Capsaicin Aspirin Ethanol info:eu-repo/semantics/article 2006 ftunimessinairis 2024-01-10T17:39:22Z An experimental, macroscopical, study was undertaken in european eel (Anguilla anguilla) to assess the gastro-protective effect of capsaicin, the active component contained in pepper. Gastric bags were prepared from specimens of Anguilla anguilla and used for in vitro study of the ability of capsaicin to recover ulcers induced by aspirin or ethanol. Gastric ulcers were experimentally induced and comparison was made with the same experiment repeated in presence of capsaicin at different concentrations (10-6, 10-5, 10-4 mol/l). Macroscopical observations showed that capsaicin at low doses (10-6 mol/l) was effective in repairing the mucosal layer injured, thus proving in vitro its protective effect on the gastrointestinal tract of this fish species. Moreover, the similar physiological behaviour of the protective effect found between our study and other in vivo studies performed on rats supported the possibility of using the gastro-intestinal tract of eel as a model substrate for pharmacological and toxicological studies Article in Journal/Newspaper Anguilla anguilla European eel Università degli Studi di Messina: IRIS |
institution |
Open Polar |
collection |
Università degli Studi di Messina: IRIS |
op_collection_id |
ftunimessinairis |
language |
English |
topic |
Anguilla anguilla Gastric ulcer Capsaicin Aspirin Ethanol |
spellingShingle |
Anguilla anguilla Gastric ulcer Capsaicin Aspirin Ethanol DENARO, Maria Gabr. CARUSO G GENOVESE L. Gastro-protective effect of capsaicin in Anguilla anguilla (Linneus, 1758): evidence from an experimental study on gastric bags. |
topic_facet |
Anguilla anguilla Gastric ulcer Capsaicin Aspirin Ethanol |
description |
An experimental, macroscopical, study was undertaken in european eel (Anguilla anguilla) to assess the gastro-protective effect of capsaicin, the active component contained in pepper. Gastric bags were prepared from specimens of Anguilla anguilla and used for in vitro study of the ability of capsaicin to recover ulcers induced by aspirin or ethanol. Gastric ulcers were experimentally induced and comparison was made with the same experiment repeated in presence of capsaicin at different concentrations (10-6, 10-5, 10-4 mol/l). Macroscopical observations showed that capsaicin at low doses (10-6 mol/l) was effective in repairing the mucosal layer injured, thus proving in vitro its protective effect on the gastrointestinal tract of this fish species. Moreover, the similar physiological behaviour of the protective effect found between our study and other in vivo studies performed on rats supported the possibility of using the gastro-intestinal tract of eel as a model substrate for pharmacological and toxicological studies |
author2 |
Denaro, Maria Gabr. Caruso, G Genovese, L. |
format |
Article in Journal/Newspaper |
author |
DENARO, Maria Gabr. CARUSO G GENOVESE L. |
author_facet |
DENARO, Maria Gabr. CARUSO G GENOVESE L. |
author_sort |
DENARO, Maria Gabr. |
title |
Gastro-protective effect of capsaicin in Anguilla anguilla (Linneus, 1758): evidence from an experimental study on gastric bags. |
title_short |
Gastro-protective effect of capsaicin in Anguilla anguilla (Linneus, 1758): evidence from an experimental study on gastric bags. |
title_full |
Gastro-protective effect of capsaicin in Anguilla anguilla (Linneus, 1758): evidence from an experimental study on gastric bags. |
title_fullStr |
Gastro-protective effect of capsaicin in Anguilla anguilla (Linneus, 1758): evidence from an experimental study on gastric bags. |
title_full_unstemmed |
Gastro-protective effect of capsaicin in Anguilla anguilla (Linneus, 1758): evidence from an experimental study on gastric bags. |
title_sort |
gastro-protective effect of capsaicin in anguilla anguilla (linneus, 1758): evidence from an experimental study on gastric bags. |
publishDate |
2006 |
url |
http://hdl.handle.net/11570/1889770 |
genre |
Anguilla anguilla European eel |
genre_facet |
Anguilla anguilla European eel |
op_relation |
volume:3 (3) firstpage:263 lastpage:271 numberofpages:9 journal:ITTIOPATOLOGIA http://hdl.handle.net/11570/1889770 |
_version_ |
1789961609039314944 |