Photoperiodism in voles:A neurobiological perspective on seasonal ecology
Many organisms use photoperiod as a proxy to time seasonal rhythms in reproduction. Metabolic effects on the reproductive axis also affect fertility. In this thesis I investigated the interaction between proximate energetic and predictive photoperiodic cues in voles, herbivorous key species in many...
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ftunigroningenpu:oai:pure.rug.nl:publications/f4d0d950-2601-472c-83c6-5789d7164625 2024-06-02T08:10:26+00:00 Photoperiodism in voles:A neurobiological perspective on seasonal ecology van Rosmalen, Laura 2021 application/pdf https://hdl.handle.net/11370/f4d0d950-2601-472c-83c6-5789d7164625 https://research.rug.nl/en/publications/f4d0d950-2601-472c-83c6-5789d7164625 https://doi.org/10.33612/diss.178039805 https://pure.rug.nl/ws/files/178039807/Title_and_contents.pdf https://pure.rug.nl/ws/files/178039809/Chapter_1.pdf https://pure.rug.nl/ws/files/178039811/Chapter_2.pdf https://pure.rug.nl/ws/files/178039813/Chapter_3.pdf https://pure.rug.nl/ws/files/178039815/Chapter_4.pdf https://pure.rug.nl/ws/files/178039817/Chapter_5.pdf https://pure.rug.nl/ws/files/178039819/Chapter_6.pdf https://pure.rug.nl/ws/files/178039821/Chapter_7.pdf https://pure.rug.nl/ws/files/178039823/Chapter_8.pdf https://pure.rug.nl/ws/files/178039825/Chapter_9.pdf https://pure.rug.nl/ws/files/178039827/Chapter_10.pdf https://pure.rug.nl/ws/files/178039829/Appendices.pdf https://pure.rug.nl/ws/files/178039831/Complete_thesis.pdf https://pure.rug.nl/ws/files/178039833/Propositions.pdf eng eng University of Groningen https://research.rug.nl/en/publications/f4d0d950-2601-472c-83c6-5789d7164625 info:eu-repo/semantics/openAccess van Rosmalen , L 2021 , ' Photoperiodism in voles : A neurobiological perspective on seasonal ecology ' , Doctor of Philosophy , University of Groningen , [Groningen] . https://doi.org/10.33612/diss.178039805 book 2021 ftunigroningenpu https://doi.org/10.33612/diss.178039805 2024-05-07T21:14:29Z Many organisms use photoperiod as a proxy to time seasonal rhythms in reproduction. Metabolic effects on the reproductive axis also affect fertility. In this thesis I investigated the interaction between proximate energetic and predictive photoperiodic cues in voles, herbivorous key species in many ecosystems. The documented variation in breeding strategy of voles is exploited for studying the interactions of environmental variables. I measured neuroendocrine and physiological responses of Northern tundra voles (Microtus oeconomus) and Southern common voles (Microtus arvalis) to photoperiod in relation to maternal photoperiod, temperature and food scarcity. We demonstrated that maternal photoperiod- and temperature-dependent modulation of photoperiodic responses manifest in the thyrotrophin-sensitive tanycytes of the medio-basal hypothalamus. By implementing the ‘work-for-food’ paradigm we were able to induce a negative energy balance and interestingly, voles responded by shifting from nocturnal circadian activity patterns to ultradian activity patterns. In addition, food-dependent modulation of photoperiodic responses manifest in the melatonin-sensitive pars tuberalis and hypothalamus. These effects resulted in delayed reproductive organ development in spring-programmed voles when temperatures were high or when food was scarce. Furthermore, we found that the Tsh-receptor, which plays a pivotal role in the sensitivity to photoperiod, was targeted by natural selection, resulting in optimized timing of seasonal reproduction. The results presented in this thesis define a mechanistic hierarchy for the integration of metabolic and photoperiodic cues in the mammalian reproductive system, which will be important for a better understanding of how environmental cues impact reproduction and ecological balances in the food web in a changing climate. Book Microtus arvalis Tundra University of Groningen research database |
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Open Polar |
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University of Groningen research database |
op_collection_id |
ftunigroningenpu |
language |
English |
description |
Many organisms use photoperiod as a proxy to time seasonal rhythms in reproduction. Metabolic effects on the reproductive axis also affect fertility. In this thesis I investigated the interaction between proximate energetic and predictive photoperiodic cues in voles, herbivorous key species in many ecosystems. The documented variation in breeding strategy of voles is exploited for studying the interactions of environmental variables. I measured neuroendocrine and physiological responses of Northern tundra voles (Microtus oeconomus) and Southern common voles (Microtus arvalis) to photoperiod in relation to maternal photoperiod, temperature and food scarcity. We demonstrated that maternal photoperiod- and temperature-dependent modulation of photoperiodic responses manifest in the thyrotrophin-sensitive tanycytes of the medio-basal hypothalamus. By implementing the ‘work-for-food’ paradigm we were able to induce a negative energy balance and interestingly, voles responded by shifting from nocturnal circadian activity patterns to ultradian activity patterns. In addition, food-dependent modulation of photoperiodic responses manifest in the melatonin-sensitive pars tuberalis and hypothalamus. These effects resulted in delayed reproductive organ development in spring-programmed voles when temperatures were high or when food was scarce. Furthermore, we found that the Tsh-receptor, which plays a pivotal role in the sensitivity to photoperiod, was targeted by natural selection, resulting in optimized timing of seasonal reproduction. The results presented in this thesis define a mechanistic hierarchy for the integration of metabolic and photoperiodic cues in the mammalian reproductive system, which will be important for a better understanding of how environmental cues impact reproduction and ecological balances in the food web in a changing climate. |
format |
Book |
author |
van Rosmalen, Laura |
spellingShingle |
van Rosmalen, Laura Photoperiodism in voles:A neurobiological perspective on seasonal ecology |
author_facet |
van Rosmalen, Laura |
author_sort |
van Rosmalen, Laura |
title |
Photoperiodism in voles:A neurobiological perspective on seasonal ecology |
title_short |
Photoperiodism in voles:A neurobiological perspective on seasonal ecology |
title_full |
Photoperiodism in voles:A neurobiological perspective on seasonal ecology |
title_fullStr |
Photoperiodism in voles:A neurobiological perspective on seasonal ecology |
title_full_unstemmed |
Photoperiodism in voles:A neurobiological perspective on seasonal ecology |
title_sort |
photoperiodism in voles:a neurobiological perspective on seasonal ecology |
publisher |
University of Groningen |
publishDate |
2021 |
url |
https://hdl.handle.net/11370/f4d0d950-2601-472c-83c6-5789d7164625 https://research.rug.nl/en/publications/f4d0d950-2601-472c-83c6-5789d7164625 https://doi.org/10.33612/diss.178039805 https://pure.rug.nl/ws/files/178039807/Title_and_contents.pdf https://pure.rug.nl/ws/files/178039809/Chapter_1.pdf https://pure.rug.nl/ws/files/178039811/Chapter_2.pdf https://pure.rug.nl/ws/files/178039813/Chapter_3.pdf https://pure.rug.nl/ws/files/178039815/Chapter_4.pdf https://pure.rug.nl/ws/files/178039817/Chapter_5.pdf https://pure.rug.nl/ws/files/178039819/Chapter_6.pdf https://pure.rug.nl/ws/files/178039821/Chapter_7.pdf https://pure.rug.nl/ws/files/178039823/Chapter_8.pdf https://pure.rug.nl/ws/files/178039825/Chapter_9.pdf https://pure.rug.nl/ws/files/178039827/Chapter_10.pdf https://pure.rug.nl/ws/files/178039829/Appendices.pdf https://pure.rug.nl/ws/files/178039831/Complete_thesis.pdf https://pure.rug.nl/ws/files/178039833/Propositions.pdf |
genre |
Microtus arvalis Tundra |
genre_facet |
Microtus arvalis Tundra |
op_source |
van Rosmalen , L 2021 , ' Photoperiodism in voles : A neurobiological perspective on seasonal ecology ' , Doctor of Philosophy , University of Groningen , [Groningen] . https://doi.org/10.33612/diss.178039805 |
op_relation |
https://research.rug.nl/en/publications/f4d0d950-2601-472c-83c6-5789d7164625 |
op_rights |
info:eu-repo/semantics/openAccess |
op_doi |
https://doi.org/10.33612/diss.178039805 |
_version_ |
1800756306008604672 |