Reduced telomere length in offspring of old fathers in a long-lived seabird
Evidence for transgenerational effects of senescence, whereby offspring from older parents have a reduced lifetime reproductive success, is increasing. Such effects could arise from compromised germline maintenance in old parents, potentially reflected in reduced telomere length in their offspring....
Published in: | Biology Letters |
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Format: | Article in Journal/Newspaper |
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2018
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Online Access: | https://hdl.handle.net/11370/959cc568-633d-4388-a68a-a155c2e51024 https://research.rug.nl/en/publications/959cc568-633d-4388-a68a-a155c2e51024 https://doi.org/10.1098/rsbl.2018.0213 https://pure.rug.nl/ws/files/62876470/BouwhuisS_etal_BiolLett_2018_paternal_age_telomere.pdf |
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ftunigroningenpu:oai:pure.rug.nl:publications/959cc568-633d-4388-a68a-a155c2e51024 2024-09-15T18:02:45+00:00 Reduced telomere length in offspring of old fathers in a long-lived seabird Bouwhuis, Sandra Verhulst, Simon Bauch, Christina Vedder, Oscar 2018-06 application/pdf https://hdl.handle.net/11370/959cc568-633d-4388-a68a-a155c2e51024 https://research.rug.nl/en/publications/959cc568-633d-4388-a68a-a155c2e51024 https://doi.org/10.1098/rsbl.2018.0213 https://pure.rug.nl/ws/files/62876470/BouwhuisS_etal_BiolLett_2018_paternal_age_telomere.pdf eng eng https://research.rug.nl/en/publications/959cc568-633d-4388-a68a-a155c2e51024 info:eu-repo/semantics/openAccess Bouwhuis , S , Verhulst , S , Bauch , C & Vedder , O 2018 , ' Reduced telomere length in offspring of old fathers in a long-lived seabird ' , Biology Letters , vol. 14 , no. 6 , 20180213 . https://doi.org/10.1098/rsbl.2018.0213 ageing common tern Lansing effect parental effect Sterna hirundo terminal restriction fragment analysis AGE FITNESS POPULATION article 2018 ftunigroningenpu https://doi.org/10.1098/rsbl.2018.0213 2024-07-01T14:49:23Z Evidence for transgenerational effects of senescence, whereby offspring from older parents have a reduced lifetime reproductive success, is increasing. Such effects could arise from compromised germline maintenance in old parents, potentially reflected in reduced telomere length in their offspring. We test the relationship between parental age and offspring early-life telomere length in a natural population of common terns and find a significant negative correlation between paternal age and offspring telomere length. Offspring telomere length is reduced by 35 base pairs for each additional year of paternal age. We find no correlation with maternal age. These results fit with the idea of compromised germline maintenance in males, whose germline stem cells require continued division. Article in Journal/Newspaper Common tern Sterna hirundo University of Groningen research database Biology Letters 14 6 20180213 |
institution |
Open Polar |
collection |
University of Groningen research database |
op_collection_id |
ftunigroningenpu |
language |
English |
topic |
ageing common tern Lansing effect parental effect Sterna hirundo terminal restriction fragment analysis AGE FITNESS POPULATION |
spellingShingle |
ageing common tern Lansing effect parental effect Sterna hirundo terminal restriction fragment analysis AGE FITNESS POPULATION Bouwhuis, Sandra Verhulst, Simon Bauch, Christina Vedder, Oscar Reduced telomere length in offspring of old fathers in a long-lived seabird |
topic_facet |
ageing common tern Lansing effect parental effect Sterna hirundo terminal restriction fragment analysis AGE FITNESS POPULATION |
description |
Evidence for transgenerational effects of senescence, whereby offspring from older parents have a reduced lifetime reproductive success, is increasing. Such effects could arise from compromised germline maintenance in old parents, potentially reflected in reduced telomere length in their offspring. We test the relationship between parental age and offspring early-life telomere length in a natural population of common terns and find a significant negative correlation between paternal age and offspring telomere length. Offspring telomere length is reduced by 35 base pairs for each additional year of paternal age. We find no correlation with maternal age. These results fit with the idea of compromised germline maintenance in males, whose germline stem cells require continued division. |
format |
Article in Journal/Newspaper |
author |
Bouwhuis, Sandra Verhulst, Simon Bauch, Christina Vedder, Oscar |
author_facet |
Bouwhuis, Sandra Verhulst, Simon Bauch, Christina Vedder, Oscar |
author_sort |
Bouwhuis, Sandra |
title |
Reduced telomere length in offspring of old fathers in a long-lived seabird |
title_short |
Reduced telomere length in offspring of old fathers in a long-lived seabird |
title_full |
Reduced telomere length in offspring of old fathers in a long-lived seabird |
title_fullStr |
Reduced telomere length in offspring of old fathers in a long-lived seabird |
title_full_unstemmed |
Reduced telomere length in offspring of old fathers in a long-lived seabird |
title_sort |
reduced telomere length in offspring of old fathers in a long-lived seabird |
publishDate |
2018 |
url |
https://hdl.handle.net/11370/959cc568-633d-4388-a68a-a155c2e51024 https://research.rug.nl/en/publications/959cc568-633d-4388-a68a-a155c2e51024 https://doi.org/10.1098/rsbl.2018.0213 https://pure.rug.nl/ws/files/62876470/BouwhuisS_etal_BiolLett_2018_paternal_age_telomere.pdf |
genre |
Common tern Sterna hirundo |
genre_facet |
Common tern Sterna hirundo |
op_source |
Bouwhuis , S , Verhulst , S , Bauch , C & Vedder , O 2018 , ' Reduced telomere length in offspring of old fathers in a long-lived seabird ' , Biology Letters , vol. 14 , no. 6 , 20180213 . https://doi.org/10.1098/rsbl.2018.0213 |
op_relation |
https://research.rug.nl/en/publications/959cc568-633d-4388-a68a-a155c2e51024 |
op_rights |
info:eu-repo/semantics/openAccess |
op_doi |
https://doi.org/10.1098/rsbl.2018.0213 |
container_title |
Biology Letters |
container_volume |
14 |
container_issue |
6 |
container_start_page |
20180213 |
_version_ |
1810440170368925696 |