Preferences for prenatal tests for Down syndrome:an international comparison of the views of pregnant women and health professionals
Non-invasive prenatal testing is increasingly available worldwide and stakeholder viewpoints are essential to guide implementation. Here we compare the preferences of women and health professionals from nine different countries towards attributes of non-invasive and invasive prenatal tests for Down...
Published in: | European Journal of Human Genetics |
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2016
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Online Access: | https://hdl.handle.net/11370/5b280ffe-0f63-4e80-a150-53b1b186cef5 https://research.rug.nl/en/publications/5b280ffe-0f63-4e80-a150-53b1b186cef5 https://doi.org/10.1038/ejhg.2015.249 |
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ftunigroningenpu:oai:pure.rug.nl:publications/5b280ffe-0f63-4e80-a150-53b1b186cef5 2024-09-09T19:47:20+00:00 Preferences for prenatal tests for Down syndrome:an international comparison of the views of pregnant women and health professionals Hill, Melissa Johnson, Jo-Ann Langlois, Sylvie Lee, Hyun Winsor, Stephanie Dineley, Brigid Horniachek, Marisa Lalatta, Faustina Ronzoni, Luisa Barrett, Angela N. Advani, Henna V. Choolani, Mahesh Rabinowitz, Ron Pajkrt, Eva van Schendel, Rachel V. Henneman, Lidewij Rommers, Wieke Bilardo, Caterina M. Rendeiro, Paula Ribeiro, Maria Joao Rocha, Jose Lund, Ida Charlotte Bay Petersen, Olav B. Becher, Naja Vogel, Ida Stefansdottir, Vigdis Ingvarsdottir, Sigrun Gottfredsdottir, Helga Morris, Stephen Chitty, Lyn S. 2016-07 https://hdl.handle.net/11370/5b280ffe-0f63-4e80-a150-53b1b186cef5 https://research.rug.nl/en/publications/5b280ffe-0f63-4e80-a150-53b1b186cef5 https://doi.org/10.1038/ejhg.2015.249 eng eng https://research.rug.nl/en/publications/5b280ffe-0f63-4e80-a150-53b1b186cef5 info:eu-repo/semantics/closedAccess Hill , M , Johnson , J-A , Langlois , S , Lee , H , Winsor , S , Dineley , B , Horniachek , M , Lalatta , F , Ronzoni , L , Barrett , A N , Advani , H V , Choolani , M , Rabinowitz , R , Pajkrt , E , van Schendel , R V , Henneman , L , Rommers , W , Bilardo , C M , Rendeiro , P , Ribeiro , M J , Rocha , J , Lund , I C B , Petersen , O B , Becher , N , Vogel , I , Stefansdottir , V , Ingvarsdottir , S , Gottfredsdottir , H , Morris , S & Chitty , L S 2016 , ' Preferences for prenatal tests for Down syndrome : an international comparison of the views of pregnant women and health professionals ' , European Journal of Human Genetics , vol. 24 , no. 7 , pp. 968-975 . https://doi.org/10.1038/ejhg.2015.249 DISCRETE-CHOICE EXPERIMENT SYNDROME SCREENING-TESTS CELL-FREE DNA NONINVASIVE DIAGNOSIS DECISION-MAKING MATERNAL BLOOD ANEUPLOIDY NIPT NETHERLANDS ATTITUDES article 2016 ftunigroningenpu https://doi.org/10.1038/ejhg.2015.249 2024-06-17T16:10:13Z Non-invasive prenatal testing is increasingly available worldwide and stakeholder viewpoints are essential to guide implementation. Here we compare the preferences of women and health professionals from nine different countries towards attributes of non-invasive and invasive prenatal tests for Down syndrome. A discrete choice experiment was used to obtain participants' stated preference for prenatal tests that varied according to four attributes: accuracy, time of test, risk of miscarriage, and type of information. Pregnant women and health professionals were recruited from Canada, Denmark, Iceland, Israel, Italy, the Netherlands, Portugal, Singapore, and the United Kingdom. A total of 2666 women's and 1245 health professionals' questionnaires were included in the analysis. Differences in preferences were seen between women and health professionals within and between countries. Overall, women placed greater emphasis on test safety and comprehensive information than health professionals, who emphasised accuracy and early testing. Differences between women's and health professionals' preferences are marked between countries. Varied approaches to implementation and service delivery are therefore needed and individual countries should develop guidelines appropriate for their own social and screening contexts. Article in Journal/Newspaper Iceland University of Groningen research database Canada European Journal of Human Genetics 24 7 968 975 |
institution |
Open Polar |
collection |
University of Groningen research database |
op_collection_id |
ftunigroningenpu |
language |
English |
topic |
DISCRETE-CHOICE EXPERIMENT SYNDROME SCREENING-TESTS CELL-FREE DNA NONINVASIVE DIAGNOSIS DECISION-MAKING MATERNAL BLOOD ANEUPLOIDY NIPT NETHERLANDS ATTITUDES |
spellingShingle |
DISCRETE-CHOICE EXPERIMENT SYNDROME SCREENING-TESTS CELL-FREE DNA NONINVASIVE DIAGNOSIS DECISION-MAKING MATERNAL BLOOD ANEUPLOIDY NIPT NETHERLANDS ATTITUDES Hill, Melissa Johnson, Jo-Ann Langlois, Sylvie Lee, Hyun Winsor, Stephanie Dineley, Brigid Horniachek, Marisa Lalatta, Faustina Ronzoni, Luisa Barrett, Angela N. Advani, Henna V. Choolani, Mahesh Rabinowitz, Ron Pajkrt, Eva van Schendel, Rachel V. Henneman, Lidewij Rommers, Wieke Bilardo, Caterina M. Rendeiro, Paula Ribeiro, Maria Joao Rocha, Jose Lund, Ida Charlotte Bay Petersen, Olav B. Becher, Naja Vogel, Ida Stefansdottir, Vigdis Ingvarsdottir, Sigrun Gottfredsdottir, Helga Morris, Stephen Chitty, Lyn S. Preferences for prenatal tests for Down syndrome:an international comparison of the views of pregnant women and health professionals |
topic_facet |
DISCRETE-CHOICE EXPERIMENT SYNDROME SCREENING-TESTS CELL-FREE DNA NONINVASIVE DIAGNOSIS DECISION-MAKING MATERNAL BLOOD ANEUPLOIDY NIPT NETHERLANDS ATTITUDES |
description |
Non-invasive prenatal testing is increasingly available worldwide and stakeholder viewpoints are essential to guide implementation. Here we compare the preferences of women and health professionals from nine different countries towards attributes of non-invasive and invasive prenatal tests for Down syndrome. A discrete choice experiment was used to obtain participants' stated preference for prenatal tests that varied according to four attributes: accuracy, time of test, risk of miscarriage, and type of information. Pregnant women and health professionals were recruited from Canada, Denmark, Iceland, Israel, Italy, the Netherlands, Portugal, Singapore, and the United Kingdom. A total of 2666 women's and 1245 health professionals' questionnaires were included in the analysis. Differences in preferences were seen between women and health professionals within and between countries. Overall, women placed greater emphasis on test safety and comprehensive information than health professionals, who emphasised accuracy and early testing. Differences between women's and health professionals' preferences are marked between countries. Varied approaches to implementation and service delivery are therefore needed and individual countries should develop guidelines appropriate for their own social and screening contexts. |
format |
Article in Journal/Newspaper |
author |
Hill, Melissa Johnson, Jo-Ann Langlois, Sylvie Lee, Hyun Winsor, Stephanie Dineley, Brigid Horniachek, Marisa Lalatta, Faustina Ronzoni, Luisa Barrett, Angela N. Advani, Henna V. Choolani, Mahesh Rabinowitz, Ron Pajkrt, Eva van Schendel, Rachel V. Henneman, Lidewij Rommers, Wieke Bilardo, Caterina M. Rendeiro, Paula Ribeiro, Maria Joao Rocha, Jose Lund, Ida Charlotte Bay Petersen, Olav B. Becher, Naja Vogel, Ida Stefansdottir, Vigdis Ingvarsdottir, Sigrun Gottfredsdottir, Helga Morris, Stephen Chitty, Lyn S. |
author_facet |
Hill, Melissa Johnson, Jo-Ann Langlois, Sylvie Lee, Hyun Winsor, Stephanie Dineley, Brigid Horniachek, Marisa Lalatta, Faustina Ronzoni, Luisa Barrett, Angela N. Advani, Henna V. Choolani, Mahesh Rabinowitz, Ron Pajkrt, Eva van Schendel, Rachel V. Henneman, Lidewij Rommers, Wieke Bilardo, Caterina M. Rendeiro, Paula Ribeiro, Maria Joao Rocha, Jose Lund, Ida Charlotte Bay Petersen, Olav B. Becher, Naja Vogel, Ida Stefansdottir, Vigdis Ingvarsdottir, Sigrun Gottfredsdottir, Helga Morris, Stephen Chitty, Lyn S. |
author_sort |
Hill, Melissa |
title |
Preferences for prenatal tests for Down syndrome:an international comparison of the views of pregnant women and health professionals |
title_short |
Preferences for prenatal tests for Down syndrome:an international comparison of the views of pregnant women and health professionals |
title_full |
Preferences for prenatal tests for Down syndrome:an international comparison of the views of pregnant women and health professionals |
title_fullStr |
Preferences for prenatal tests for Down syndrome:an international comparison of the views of pregnant women and health professionals |
title_full_unstemmed |
Preferences for prenatal tests for Down syndrome:an international comparison of the views of pregnant women and health professionals |
title_sort |
preferences for prenatal tests for down syndrome:an international comparison of the views of pregnant women and health professionals |
publishDate |
2016 |
url |
https://hdl.handle.net/11370/5b280ffe-0f63-4e80-a150-53b1b186cef5 https://research.rug.nl/en/publications/5b280ffe-0f63-4e80-a150-53b1b186cef5 https://doi.org/10.1038/ejhg.2015.249 |
geographic |
Canada |
geographic_facet |
Canada |
genre |
Iceland |
genre_facet |
Iceland |
op_source |
Hill , M , Johnson , J-A , Langlois , S , Lee , H , Winsor , S , Dineley , B , Horniachek , M , Lalatta , F , Ronzoni , L , Barrett , A N , Advani , H V , Choolani , M , Rabinowitz , R , Pajkrt , E , van Schendel , R V , Henneman , L , Rommers , W , Bilardo , C M , Rendeiro , P , Ribeiro , M J , Rocha , J , Lund , I C B , Petersen , O B , Becher , N , Vogel , I , Stefansdottir , V , Ingvarsdottir , S , Gottfredsdottir , H , Morris , S & Chitty , L S 2016 , ' Preferences for prenatal tests for Down syndrome : an international comparison of the views of pregnant women and health professionals ' , European Journal of Human Genetics , vol. 24 , no. 7 , pp. 968-975 . https://doi.org/10.1038/ejhg.2015.249 |
op_relation |
https://research.rug.nl/en/publications/5b280ffe-0f63-4e80-a150-53b1b186cef5 |
op_rights |
info:eu-repo/semantics/closedAccess |
op_doi |
https://doi.org/10.1038/ejhg.2015.249 |
container_title |
European Journal of Human Genetics |
container_volume |
24 |
container_issue |
7 |
container_start_page |
968 |
op_container_end_page |
975 |
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1809916803993829376 |