EFFECT OF ARTERIALLY INFUSED CATECHOLAMINES AND INSULIN ON PLASMA-GLUCOSE AND FREE FATTY-ACIDS IN CARP
Common carp (Cyprinus carpio L.), kept at 20 degrees C, were fitted with an indwelling PE-50 cannula in the dorsal aorta. Hormones dissolved in Ringer saline were arterially infused at a rate of 1 mu g . kg(-1). min(-1) for epinephrine (Epi), 2 mu g . kg(-1). min(-1) for norepinephrine (NE), and 1.3...
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Language: | English |
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1995
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Online Access: | https://hdl.handle.net/11370/4b912416-af1d-4ab5-adc4-cfef01139eff https://research.rug.nl/en/publications/4b912416-af1d-4ab5-adc4-cfef01139eff |
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ftunigroningenpu:oai:pure.rug.nl:publications/4b912416-af1d-4ab5-adc4-cfef01139eff 2024-06-02T07:55:12+00:00 EFFECT OF ARTERIALLY INFUSED CATECHOLAMINES AND INSULIN ON PLASMA-GLUCOSE AND FREE FATTY-ACIDS IN CARP VANRAAIJ, MTM VANDENTHILLART, GEEJM HALLEMEESCH, M BALM, PHM STEFFENS, AB 1995-05 https://hdl.handle.net/11370/4b912416-af1d-4ab5-adc4-cfef01139eff https://research.rug.nl/en/publications/4b912416-af1d-4ab5-adc4-cfef01139eff eng eng https://research.rug.nl/en/publications/4b912416-af1d-4ab5-adc4-cfef01139eff info:eu-repo/semantics/restrictedAccess VANRAAIJ , MTM , VANDENTHILLART , GEEJM , HALLEMEESCH , M , BALM , PHM & STEFFENS , AB 1995 , ' EFFECT OF ARTERIALLY INFUSED CATECHOLAMINES AND INSULIN ON PLASMA-GLUCOSE AND FREE FATTY-ACIDS IN CARP ' , American journal of physiology-Regulatory integrative and comparative physiology , vol. 268 , no. 5 , pp. R1163-R1170 . EPINEPHRINE NOREPINEPHRINE CYPRINUS CARPIO L EUROPEAN SILVER EEL ANGUILLA-ANGUILLA-L ESOX-LUCIUS L LIPID MOBILIZATION RAINBOW-TROUT ISOLATED HEPATOCYTES BLOOD METABOLITES NORTHERN PIKE GLUCAGON FISH article 1995 ftunigroningenpu 2024-05-07T19:11:15Z Common carp (Cyprinus carpio L.), kept at 20 degrees C, were fitted with an indwelling PE-50 cannula in the dorsal aorta. Hormones dissolved in Ringer saline were arterially infused at a rate of 1 mu g . kg(-1). min(-1) for epinephrine (Epi), 2 mu g . kg(-1). min(-1) for norepinephrine (NE), and 1.33 mu g . kg(-1). min(-1) for insulin. Infusion of bovine insulin in carp resulted in a long lasting (24 h) decrease of plasma free fatty acids (FFA; -0.41 +/- 0.06 mM) and glucose levels (-3.14 +/- 0.25 mM) compared with preinfusion levels at t = 0. Both Epi and NE induced a marked hyperglycemia although Epi was more potent (+8.2 +/- 0.9 and +6.9 +/- 0.8 mM, respectively). Plasma FFA levels increased by 0.25 +/- 0.03 mM compared with preinfusion levels on Epi infusion. In contrast, during NE infusion, plasma FFA levels decreased significantly by -0.21 +/- 0.03 mM. Plasma insulin titers did not significantly change during infusion of NE or Epi. It is concluded that the ratio of NE to Epi is the major factor that determines the effect of catecholamines on plasma FFA levels in carp. These results may explain species-dependent different effects of hypoxia on FFA metabolism in fish. Article in Journal/Newspaper Anguilla anguilla University of Groningen research database Ringer ENVELOPE(162.050,162.050,-77.250,-77.250) |
institution |
Open Polar |
collection |
University of Groningen research database |
op_collection_id |
ftunigroningenpu |
language |
English |
topic |
EPINEPHRINE NOREPINEPHRINE CYPRINUS CARPIO L EUROPEAN SILVER EEL ANGUILLA-ANGUILLA-L ESOX-LUCIUS L LIPID MOBILIZATION RAINBOW-TROUT ISOLATED HEPATOCYTES BLOOD METABOLITES NORTHERN PIKE GLUCAGON FISH |
spellingShingle |
EPINEPHRINE NOREPINEPHRINE CYPRINUS CARPIO L EUROPEAN SILVER EEL ANGUILLA-ANGUILLA-L ESOX-LUCIUS L LIPID MOBILIZATION RAINBOW-TROUT ISOLATED HEPATOCYTES BLOOD METABOLITES NORTHERN PIKE GLUCAGON FISH VANRAAIJ, MTM VANDENTHILLART, GEEJM HALLEMEESCH, M BALM, PHM STEFFENS, AB EFFECT OF ARTERIALLY INFUSED CATECHOLAMINES AND INSULIN ON PLASMA-GLUCOSE AND FREE FATTY-ACIDS IN CARP |
topic_facet |
EPINEPHRINE NOREPINEPHRINE CYPRINUS CARPIO L EUROPEAN SILVER EEL ANGUILLA-ANGUILLA-L ESOX-LUCIUS L LIPID MOBILIZATION RAINBOW-TROUT ISOLATED HEPATOCYTES BLOOD METABOLITES NORTHERN PIKE GLUCAGON FISH |
description |
Common carp (Cyprinus carpio L.), kept at 20 degrees C, were fitted with an indwelling PE-50 cannula in the dorsal aorta. Hormones dissolved in Ringer saline were arterially infused at a rate of 1 mu g . kg(-1). min(-1) for epinephrine (Epi), 2 mu g . kg(-1). min(-1) for norepinephrine (NE), and 1.33 mu g . kg(-1). min(-1) for insulin. Infusion of bovine insulin in carp resulted in a long lasting (24 h) decrease of plasma free fatty acids (FFA; -0.41 +/- 0.06 mM) and glucose levels (-3.14 +/- 0.25 mM) compared with preinfusion levels at t = 0. Both Epi and NE induced a marked hyperglycemia although Epi was more potent (+8.2 +/- 0.9 and +6.9 +/- 0.8 mM, respectively). Plasma FFA levels increased by 0.25 +/- 0.03 mM compared with preinfusion levels on Epi infusion. In contrast, during NE infusion, plasma FFA levels decreased significantly by -0.21 +/- 0.03 mM. Plasma insulin titers did not significantly change during infusion of NE or Epi. It is concluded that the ratio of NE to Epi is the major factor that determines the effect of catecholamines on plasma FFA levels in carp. These results may explain species-dependent different effects of hypoxia on FFA metabolism in fish. |
format |
Article in Journal/Newspaper |
author |
VANRAAIJ, MTM VANDENTHILLART, GEEJM HALLEMEESCH, M BALM, PHM STEFFENS, AB |
author_facet |
VANRAAIJ, MTM VANDENTHILLART, GEEJM HALLEMEESCH, M BALM, PHM STEFFENS, AB |
author_sort |
VANRAAIJ, MTM |
title |
EFFECT OF ARTERIALLY INFUSED CATECHOLAMINES AND INSULIN ON PLASMA-GLUCOSE AND FREE FATTY-ACIDS IN CARP |
title_short |
EFFECT OF ARTERIALLY INFUSED CATECHOLAMINES AND INSULIN ON PLASMA-GLUCOSE AND FREE FATTY-ACIDS IN CARP |
title_full |
EFFECT OF ARTERIALLY INFUSED CATECHOLAMINES AND INSULIN ON PLASMA-GLUCOSE AND FREE FATTY-ACIDS IN CARP |
title_fullStr |
EFFECT OF ARTERIALLY INFUSED CATECHOLAMINES AND INSULIN ON PLASMA-GLUCOSE AND FREE FATTY-ACIDS IN CARP |
title_full_unstemmed |
EFFECT OF ARTERIALLY INFUSED CATECHOLAMINES AND INSULIN ON PLASMA-GLUCOSE AND FREE FATTY-ACIDS IN CARP |
title_sort |
effect of arterially infused catecholamines and insulin on plasma-glucose and free fatty-acids in carp |
publishDate |
1995 |
url |
https://hdl.handle.net/11370/4b912416-af1d-4ab5-adc4-cfef01139eff https://research.rug.nl/en/publications/4b912416-af1d-4ab5-adc4-cfef01139eff |
long_lat |
ENVELOPE(162.050,162.050,-77.250,-77.250) |
geographic |
Ringer |
geographic_facet |
Ringer |
genre |
Anguilla anguilla |
genre_facet |
Anguilla anguilla |
op_source |
VANRAAIJ , MTM , VANDENTHILLART , GEEJM , HALLEMEESCH , M , BALM , PHM & STEFFENS , AB 1995 , ' EFFECT OF ARTERIALLY INFUSED CATECHOLAMINES AND INSULIN ON PLASMA-GLUCOSE AND FREE FATTY-ACIDS IN CARP ' , American journal of physiology-Regulatory integrative and comparative physiology , vol. 268 , no. 5 , pp. R1163-R1170 . |
op_relation |
https://research.rug.nl/en/publications/4b912416-af1d-4ab5-adc4-cfef01139eff |
op_rights |
info:eu-repo/semantics/restrictedAccess |
_version_ |
1800746828160827392 |