Bifenilos policlorados y disrupción endocrina en la fauna salvaje

Los Bifenilos Policlorados son una amplia familia de contaminantes ambientales persistentes de enorme relevancia ambiental, pues a pesar de estar prohibidos, siguen encontrándose en concentraciones preocupantes en el medio ambiente, suficientes como para desencadenar programas de biomonitorizacion a...

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Published in:Observatorio Medioambiental
Main Authors: Hernández-Moreno, David, Míguez-Santiyán, María P., Oropesa-Jiménez, Ana L., Soler-Rodríguez, Francisco, van Wyk, J.H., Pérez-López, Marcos
Format: Article in Journal/Newspaper
Language:Spanish
Published: Ediciones Complutense 2016
Subjects:
Online Access:https://revistas.ucm.es/index.php/OBMD/article/view/54160
https://doi.org/10.5209/OBMD.54160
id ftunicmadridrev:oai:ojs.pkp.sfu.ca:article/54160
record_format openpolar
institution Open Polar
collection Universidad Complutense de Madrid (UCM): Revistas Científicas Complutenses
op_collection_id ftunicmadridrev
language Spanish
topic Polychlorinated biphenyls; endocrine disruptor; wildlife
Bifenilos policlorados; disruptor endocrino; fauna salvaje
Biphényles polychlorés; disrupteur endocrinien; la faune
spellingShingle Polychlorinated biphenyls; endocrine disruptor; wildlife
Bifenilos policlorados; disruptor endocrino; fauna salvaje
Biphényles polychlorés; disrupteur endocrinien; la faune
Hernández-Moreno, David
Míguez-Santiyán, María P.
Oropesa-Jiménez, Ana L.
Soler-Rodríguez, Francisco
van Wyk, J.H.
Pérez-López, Marcos
Bifenilos policlorados y disrupción endocrina en la fauna salvaje
topic_facet Polychlorinated biphenyls; endocrine disruptor; wildlife
Bifenilos policlorados; disruptor endocrino; fauna salvaje
Biphényles polychlorés; disrupteur endocrinien; la faune
description Los Bifenilos Policlorados son una amplia familia de contaminantes ambientales persistentes de enorme relevancia ambiental, pues a pesar de estar prohibidos, siguen encontrándose en concentraciones preocupantes en el medio ambiente, suficientes como para desencadenar programas de biomonitorizacion ambiental. Y en esta necesidad de seguir identificándolos y cuantificándolos se encuentra, en un punto destacado, su potencial efecto como disruptores endocrinos, tema de suma importancia desde el punto de vista de la reproducción de las especies de vida salvaje. De hecho, en las dos últimas décadas, se ha incrementado entre la comunidad científica el interés por investigar las posibles alteraciones en el funcionamiento del sistema endocrino de vertebrados e invertebrados como consecuencia de la exposición a productos químicos. En definitiva, la presente revisión resume los conocimientos más actualizados existentes sobre los Bifenilos policlorados cuantificados en la fauna salvaje, y sus principales efectos sobre la reproducción. Les biphényles polychlorés sont une grande famille de polluants environnementaux persistants d'une énorme importance pour l'environnement, parce que bien qu'ils soient interdits, on trouve encore des concentrations alarmantes dans l'environnement suffisant pour déclencher des programmes de biosurveillance de l'environnement. Et ce besoin de continuer à identifier et quantifier eux est, dans un point culminant son effet potentiel comme perturbateurs endocriniens, question importante du point de vue de la reproduction des espèces d'animaux sauvages. En fait, au cours des deux dernières décennies, il a augmenté dans l'intérêt de la communauté scientifique enquêter sur d'éventuelles modifications dans le fonctionnement du système endocrinien des vertébrés et des invertébrés à la suite de l'exposition aux produits chimiques. En bref, la présente revue résume les connaissances de la date actuelle sur les polychlorobiphényles quantifiés dans la faune sauvage, et leurs principaux effets sur la reproduction. Polychlorinated biphenyls are a broad family of persistent environmental pollutants of enormous environmental significance, because despite being prohibited, they are still found in alarming concentrations in the environment, enough to trigger environmental biomonitoring programs. Associated to this need to continue identifying and quantifying them, their potential effect as endocrine disruptors is of great relevance, being an important issue from the point of view of the reproduction of wildlife species. In fact, in the last two decades, the scientific community interest about investigating the alterations in the functioning of the endocrine system of vertebrates and invertebrates because of exposure to chemicals has increased. In short, the present review summarizes current date knowledge on polychlorinated biphenyls quantified in wildlife, and their main effects on reproduction.
format Article in Journal/Newspaper
author Hernández-Moreno, David
Míguez-Santiyán, María P.
Oropesa-Jiménez, Ana L.
Soler-Rodríguez, Francisco
van Wyk, J.H.
Pérez-López, Marcos
author_facet Hernández-Moreno, David
Míguez-Santiyán, María P.
Oropesa-Jiménez, Ana L.
Soler-Rodríguez, Francisco
van Wyk, J.H.
Pérez-López, Marcos
author_sort Hernández-Moreno, David
title Bifenilos policlorados y disrupción endocrina en la fauna salvaje
title_short Bifenilos policlorados y disrupción endocrina en la fauna salvaje
title_full Bifenilos policlorados y disrupción endocrina en la fauna salvaje
title_fullStr Bifenilos policlorados y disrupción endocrina en la fauna salvaje
title_full_unstemmed Bifenilos policlorados y disrupción endocrina en la fauna salvaje
title_sort bifenilos policlorados y disrupción endocrina en la fauna salvaje
publisher Ediciones Complutense
publishDate 2016
url https://revistas.ucm.es/index.php/OBMD/article/view/54160
https://doi.org/10.5209/OBMD.54160
long_lat ENVELOPE(-60.783,-60.783,-63.717,-63.717)
geographic Consecuencia
geographic_facet Consecuencia
genre Arctic
Polar Biology
genre_facet Arctic
Polar Biology
op_source Observatorio Medioambiental; Vol. 19 (2016); 91-109
1988-3277
1139-1987
op_relation https://revistas.ucm.es/index.php/OBMD/article/view/54160/49534
Addison , R., Muir, D., Ikonomou, M., Harwood, L., Smith, T., Alikamik, J (2014): Temporal trends in “legacy” organochlorine contaminants in blubber of ringed seals (Phoca hispida) from Ulukhaktok, NT, Canada between 1972 and 2010. Science of the Total Environment 466: 564-576.
Addison , R., Sobo, W. (2001): Trends in organochlorine residue concentrations and burdens in grey seals (Halichoerus grypus) from sable Is., NS, Canada, between 1974 and 1994. Environmental Pollution 112: 505-513.
Afghan, B.K., Chau, A.S.Y. (1989): Analysis of trace organics in the aquatic environment. Boca Raton, FL, CRC Press, pp. 33-68.
Ahlborg U.G., Becking G.C., Birnbaum L.S., Brouwera A., Derks H.J., Feeley M., Golog G., Hanberg A., Larsen J.C., Liem A.K. (1994). Toxic equivalency factors for dioxin-like PCBs: Report on WHO-ECEH and IPCS consultation. Chemosphere 28: 1049-1067.
Anderson M., Lic E., Derocher A.E., Belikov S.E., Bernhoft A., Boltunov A.N., Garner G.W., Skaare J.U., Wiig O. (2001). Geographical variation of PCB congeners in polar bears (Ursus maritimus) from Svalbard east to Chukchi Sea. Polar Biology 24: 321-238.
Andersson O., Linder C.E., Olsson M., Reutergardh L., Uvemo U.B., Wideqvist U. (1988). Spatial differences and temporal trends of organochlorine compounds in biota from the northwestern hemisphere. Archives of Environmental Contamination and Toxicology 17: 755-765.
Antón A., Lizaso J. (2001). PCBs y Dioxinas. Fundación Ibérica para la Seguridad Alimentaria. Madrid, España.
ATSDR (2000). Toxicological profile for polychlorinated biphenyls (PCBs).Atlanta, GA, US Department of Health and Human Services, Agency for Toxic Substances and Disease Registry, 765 pp.
Barron M., Galbraith H., Beltman D. (1995). Comparative reproductive and developmental toxicology of PCBs in birds. Comparative Biochemistry and Physiology Part C: Pharmacology, Toxicology and Endocrinology 112: 1-14.
Basu N., Head J. (2010). Mammalian wildlife as complementary models in environmental neurotoxicology. Neurotoxicology and Teratology 32: 114-119.
Bell M.R. (2014). Endocrine-disrupting actions of PCBs on brain development and social and reproductive behaviors. Current Opinion in Pharmacology 19: 134-144.
Beyer N.M., Meador J.P. (2001). Environmental contaminants in biota: Interpreting tissue concentrations. Ed. Taylor and Francis. Nueva York (USA).
Braune B.M., Outridge P.M., Fisk A.T., Muir D.C.G., Helm P.A., Hobbs K. (2005). Persistent organic pollutants and mercury in marine biota of the Canadian Arctic: an overview of spatial and temporal trends. Science of the Total Environment 351: 4-56.
Bursian S., Newsted J., Zwiernik M. (2012). Polychlorinated biphenyls, polybrominated biphenyls, polychlorinated dibenzo-p-dioxins, and polychlorinated dibenzofurans. En: Ramesh C. Gupta (editor). Veterinary Toxicology. Academic Press, Oxford, pp. 779-796.
Calvert J.H. (1876). Pheasant poisoning by swallowing shot. The field 47(1208): 189. Canadian Council of Ministers of the Environment (2001). Canadian tissue residue guidelines for the protection of wildlife consumers of aquatic biota: polychlorinated biphenyls (PCBs). Updated. Winipeg (Canadá).
Carson R. (1962). Silent Spring. Houghton Mifflin Company, Boston (USA).
Chacón O., Cuevas F.C., De la Fuente C., Díaz F. (2007). Disrupción endocrina e Imposex. Avances en Ciencias Veterinarias 22: 42-48.
Commission of the European Communities (2007). Commission Staff Working Document on the implementation of the "Community Strategy for Endocrine Disrupters" - a range of substances suspected of interfering with the hormone systems of humans and wildlife (COM (1999) 706), (COM (2001) 262) and (SEC (2004) 1372).
CSTEE (Scientific Committee on Toxicity, Ecotoxicity and the Environment) (1999). CSTEE opinion on human and wildlife health effects of endocrine disrupting chemicals, with emphasis on wildlife and on ecotoxicology test methods. Consumer Policy and Consumer Health Protection DG XXIV: 1-96.
Dahlgren R.B., Linder R.L., Carlson C. (1972). Polychlorinated biphenyls: their effects on penned pheasants. Environmental Health Perspectives 1: 89-101.
Daniel P. (2005). Toxic drift: pesticides and health in the post-World War II South. Louisiana State University Press. Baton Rouge (USA).
De Guise s., Lagace A., Beland P. (1994). Tumors in the St. Lawrence beluga whales (Delphinapterus leucas). Veterinary Pathology 31: 444-449.
Decisión 2006/507/CE del Consejo, de 14 de Octubre de 2004, relativa a la celebración, en nombre de la Comunidad Europea, del Convenio de Estocolmo sobre contaminantes orgánicos persistentes. Diario Oficial de la Unión Europea L209, de 31 de Julio de 2006.
Del Mazo J., Paz M., Gonzáles E., Escolar F., López-Casas P.P. (2005). Genómica funcional y proteómica en el desarrollo de testículo expuesto a disruptores endocrinos. VII Conferencia sobre disruptores endocrinos, A Coruña, 27 y 28 de Octubre de 2005. Sesión 1.
Facemire C.F., Gross T.S., Guillette L.J.J. (1995). Reproductive impairment in the Florida panther: nature or nurture? Environmental Health Perspectives 103: 79-86.
Falandysz J., Yamashita N., Tanabe S., Tutsukawa R., Rucinska L., Mizera T., Jakuczum B. (1994). Congener-specific analysis of polychlorinated biphenyls in white-tailed sea eagles Haliaeetus albicilla collected in Poland. Archives of Environmental Contamination and Toxicology 26: 13-22.
Grinell G.B. (1894). Lead poisoning. Forest and Stream 42(6): 117-118.
Helander B., Olsson M., Reutergård L. (1982). Residue levels of organochlorine and mercury compounds in unhatched eggs and the relationships to breeding success in white-tailed sea eagles Haliaeetus albicilla in Sweden. Holarctic Ecology 5: 349-366.
Helle E. (1980). Lowered reproductive capacity in female ringed seals (Phoca hispida) in the Bothnian Bay, northern Baltic Sea, with special reference to uterine occlusions. Annales Zoologici Fennici 17: 147-158.
Herrera A., Arino A., Conchello P., Lazaro R., BAYARRI S., Perez-Arquillue C., Garrido M., Jodral M., Pozo R. (1996). Estimates of mean daily intakes of persistent organochlorine pesticides from Spanish fatty foodstuffs. Bulletin of Environmental Contamination and Toxicology 56: 173-177.
Hoffman D.J., Rice C.P., Kubiak T.J. (1996). PCBs and dioxins in birds. En: Beyer WN, Heinz GH, Redmon-Norwood AW (eds.). Environmental Contaminants in Wildlife - Interpreting Tissue Concentrations. SETAC Special Publications Series, Lewis Publishers, CRC Press, Boca Raton, FL, pp. 165-207.
Interim (Secretariat of the Stockholm Convention on Persistent Organic Pollutants) (2002). Ridding the world of POPs: A guide to the Stockholm Convention on persistent organic pollutants. United Nations Environmental Programme, Suiza.
ISTAS (2000). Disruptores endocrinos: Un Nuevo riesgo tóxico. http://www.redunidadesdeigualdad.udl.cat/fileadmin/Recursos/Salud/disruptoresendocrino s.pdf (Consultado en mayo de 2015).
Jenner, M.G. (1979). Pseudohermaphroditism in Ilyanassa obsoleta. Science 205: 1407-1409.
Jensen S. (1996). Report of a new chemical hazard. New Scientist 32: 612.
Jensen S., Johnels A.G., Olsson M., Otterlind G. (1969). DDT and PCB in marine animals from Swedish waters. Nature 224: 247-250.
Kimbrough R.D. (1987). Human health effects of polychlorinated biphenyls and polybrominated biphenyls. Annual Review of Pharmacology and Toxicology 27: 87-111.
Kimbrough R.D. (1995). Polychlorinated biphenyls (PCBs) and human health: an update. Critical Reviews in Toxicology 25: 133-163.
Kubiak T.J., Harris H.J., Smith L.M., Schwartz T.R., Stalling D.L., Trick J.A., Sileo L., Docherty D.E., Erdman T.C. (1989). Microcontaminants and reproductive impairment of the Foster ́s tern on Green Bay, Lake Michigan-1983. Archives of Environmental Contamination and Toxicology 18: 706-727.
Lavado R., Thibaut R., Raldúa D., Martín R., Porte C. (2004). First evidence of endocrine disruption in feral carp from Ebro River. Toxicology and Applied Pharmacology 196: 247-257.
Leonards P.E.G. (1997). PCBs in mustelids: Analysis, food chain transfer and critical levels. Dissertation. Free University of Amsterdam.
MAGRAMA (Ministerio de Agricultura, Alimentación y Medio Ambiente)(2014).Contaminantes Orgánicos Persistentes: COPs. Enlace web: http://www.magrama.gob.es/es/calidad-y-evaluacion-ambiental/temas/productosquimicos/contaminantes-organicos-persistentes-cop/ (consultado en febrero 2015).
Martin P.A., Mcdaniel T.V., Hunter B. (2006). Temporal and spatial trends in chlorinated hydrocarbon concentrations of mink in Canadian Lakes Erie and St. Clair. Environmental. Monitoring and Assessment 113: 245-263.
MartineaU D., Lagace A., Béland P., Higgins R., Armstrong D., Shugart L.R. (1988). Pathology of stranded beluga whales (Delphinapterus leucas) from the St. Lawrence Estuary, Quebec, Canada. Journal of Comparative Pathology 98(3): 289-311.
Mossner S., Ballschmiter K. (1997). Marine mammals as global pollution indicators for organochlorines. Chemosphere 34: 1285-1296.
Muir D., Braune B., Demarch B., Norstrom R., Wagemann R., Lockhart L., Hargrave B., Bright D., Addison R., Payne J., Reimer K. (1999). Spatial and temporal trends and effects of contaminants in the Canadian Arctic marine ecosystem: a review. Science of the Total Environment 230: 83-144.
Muir D., Koczanski K., Rosemberg B., Beland P. (1996). Persistent organochlorine in Beluga whales (Delphinapterus leucas) from the St Lawrence River Estuary-II. Temporal trends, 1982-1994. Environmental Pollution 93: 235-245.
Muir D., Norstrom R.J. (2000). Geographical differences and time trends of persistent organic pollutants in the Arctic. Toxicology Letters 112-113: 93-101.
Muir D., Wagemann R., Hargrave B.T., Thomas D.J., Peakall D.B., Norstrom R.J. (1992). Arctic marine ecosystem contamination. Science of the Total Environment 122: 75-134.
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spelling ftunicmadridrev:oai:ojs.pkp.sfu.ca:article/54160 2023-05-15T14:28:18+02:00 Bifenilos policlorados y disrupción endocrina en la fauna salvaje Polychlorobiphényles et perturbation du système endocrinien chez les animaux sauvages Polychlorinated biphenyls and endocrine disruption in wildlife Hernández-Moreno, David Míguez-Santiyán, María P. Oropesa-Jiménez, Ana L. Soler-Rodríguez, Francisco van Wyk, J.H. Pérez-López, Marcos 2016-12-07 application/pdf https://revistas.ucm.es/index.php/OBMD/article/view/54160 https://doi.org/10.5209/OBMD.54160 spa spa Ediciones Complutense https://revistas.ucm.es/index.php/OBMD/article/view/54160/49534 Addison , R., Muir, D., Ikonomou, M., Harwood, L., Smith, T., Alikamik, J (2014): Temporal trends in “legacy” organochlorine contaminants in blubber of ringed seals (Phoca hispida) from Ulukhaktok, NT, Canada between 1972 and 2010. Science of the Total Environment 466: 564-576. Addison , R., Sobo, W. (2001): Trends in organochlorine residue concentrations and burdens in grey seals (Halichoerus grypus) from sable Is., NS, Canada, between 1974 and 1994. Environmental Pollution 112: 505-513. Afghan, B.K., Chau, A.S.Y. (1989): Analysis of trace organics in the aquatic environment. Boca Raton, FL, CRC Press, pp. 33-68. Ahlborg U.G., Becking G.C., Birnbaum L.S., Brouwera A., Derks H.J., Feeley M., Golog G., Hanberg A., Larsen J.C., Liem A.K. (1994). Toxic equivalency factors for dioxin-like PCBs: Report on WHO-ECEH and IPCS consultation. Chemosphere 28: 1049-1067. Anderson M., Lic E., Derocher A.E., Belikov S.E., Bernhoft A., Boltunov A.N., Garner G.W., Skaare J.U., Wiig O. (2001). Geographical variation of PCB congeners in polar bears (Ursus maritimus) from Svalbard east to Chukchi Sea. Polar Biology 24: 321-238. Andersson O., Linder C.E., Olsson M., Reutergardh L., Uvemo U.B., Wideqvist U. (1988). Spatial differences and temporal trends of organochlorine compounds in biota from the northwestern hemisphere. Archives of Environmental Contamination and Toxicology 17: 755-765. Antón A., Lizaso J. (2001). PCBs y Dioxinas. Fundación Ibérica para la Seguridad Alimentaria. Madrid, España. ATSDR (2000). Toxicological profile for polychlorinated biphenyls (PCBs).Atlanta, GA, US Department of Health and Human Services, Agency for Toxic Substances and Disease Registry, 765 pp. Barron M., Galbraith H., Beltman D. (1995). Comparative reproductive and developmental toxicology of PCBs in birds. Comparative Biochemistry and Physiology Part C: Pharmacology, Toxicology and Endocrinology 112: 1-14. Basu N., Head J. (2010). Mammalian wildlife as complementary models in environmental neurotoxicology. Neurotoxicology and Teratology 32: 114-119. Bell M.R. (2014). Endocrine-disrupting actions of PCBs on brain development and social and reproductive behaviors. Current Opinion in Pharmacology 19: 134-144. Beyer N.M., Meador J.P. (2001). Environmental contaminants in biota: Interpreting tissue concentrations. Ed. Taylor and Francis. Nueva York (USA). Braune B.M., Outridge P.M., Fisk A.T., Muir D.C.G., Helm P.A., Hobbs K. (2005). Persistent organic pollutants and mercury in marine biota of the Canadian Arctic: an overview of spatial and temporal trends. Science of the Total Environment 351: 4-56. Bursian S., Newsted J., Zwiernik M. (2012). Polychlorinated biphenyls, polybrominated biphenyls, polychlorinated dibenzo-p-dioxins, and polychlorinated dibenzofurans. En: Ramesh C. Gupta (editor). Veterinary Toxicology. Academic Press, Oxford, pp. 779-796. Calvert J.H. (1876). Pheasant poisoning by swallowing shot. The field 47(1208): 189. Canadian Council of Ministers of the Environment (2001). Canadian tissue residue guidelines for the protection of wildlife consumers of aquatic biota: polychlorinated biphenyls (PCBs). Updated. Winipeg (Canadá). Carson R. (1962). Silent Spring. Houghton Mifflin Company, Boston (USA). Chacón O., Cuevas F.C., De la Fuente C., Díaz F. (2007). Disrupción endocrina e Imposex. Avances en Ciencias Veterinarias 22: 42-48. Commission of the European Communities (2007). Commission Staff Working Document on the implementation of the "Community Strategy for Endocrine Disrupters" - a range of substances suspected of interfering with the hormone systems of humans and wildlife (COM (1999) 706), (COM (2001) 262) and (SEC (2004) 1372). CSTEE (Scientific Committee on Toxicity, Ecotoxicity and the Environment) (1999). CSTEE opinion on human and wildlife health effects of endocrine disrupting chemicals, with emphasis on wildlife and on ecotoxicology test methods. Consumer Policy and Consumer Health Protection DG XXIV: 1-96. Dahlgren R.B., Linder R.L., Carlson C. (1972). Polychlorinated biphenyls: their effects on penned pheasants. Environmental Health Perspectives 1: 89-101. Daniel P. (2005). Toxic drift: pesticides and health in the post-World War II South. Louisiana State University Press. Baton Rouge (USA). De Guise s., Lagace A., Beland P. (1994). Tumors in the St. Lawrence beluga whales (Delphinapterus leucas). Veterinary Pathology 31: 444-449. Decisión 2006/507/CE del Consejo, de 14 de Octubre de 2004, relativa a la celebración, en nombre de la Comunidad Europea, del Convenio de Estocolmo sobre contaminantes orgánicos persistentes. Diario Oficial de la Unión Europea L209, de 31 de Julio de 2006. Del Mazo J., Paz M., Gonzáles E., Escolar F., López-Casas P.P. (2005). Genómica funcional y proteómica en el desarrollo de testículo expuesto a disruptores endocrinos. VII Conferencia sobre disruptores endocrinos, A Coruña, 27 y 28 de Octubre de 2005. Sesión 1. Facemire C.F., Gross T.S., Guillette L.J.J. (1995). Reproductive impairment in the Florida panther: nature or nurture? Environmental Health Perspectives 103: 79-86. Falandysz J., Yamashita N., Tanabe S., Tutsukawa R., Rucinska L., Mizera T., Jakuczum B. (1994). Congener-specific analysis of polychlorinated biphenyls in white-tailed sea eagles Haliaeetus albicilla collected in Poland. Archives of Environmental Contamination and Toxicology 26: 13-22. Grinell G.B. (1894). Lead poisoning. Forest and Stream 42(6): 117-118. Helander B., Olsson M., Reutergård L. (1982). Residue levels of organochlorine and mercury compounds in unhatched eggs and the relationships to breeding success in white-tailed sea eagles Haliaeetus albicilla in Sweden. Holarctic Ecology 5: 349-366. Helle E. (1980). Lowered reproductive capacity in female ringed seals (Phoca hispida) in the Bothnian Bay, northern Baltic Sea, with special reference to uterine occlusions. Annales Zoologici Fennici 17: 147-158. Herrera A., Arino A., Conchello P., Lazaro R., BAYARRI S., Perez-Arquillue C., Garrido M., Jodral M., Pozo R. (1996). Estimates of mean daily intakes of persistent organochlorine pesticides from Spanish fatty foodstuffs. Bulletin of Environmental Contamination and Toxicology 56: 173-177. Hoffman D.J., Rice C.P., Kubiak T.J. (1996). PCBs and dioxins in birds. En: Beyer WN, Heinz GH, Redmon-Norwood AW (eds.). Environmental Contaminants in Wildlife - Interpreting Tissue Concentrations. SETAC Special Publications Series, Lewis Publishers, CRC Press, Boca Raton, FL, pp. 165-207. Interim (Secretariat of the Stockholm Convention on Persistent Organic Pollutants) (2002). Ridding the world of POPs: A guide to the Stockholm Convention on persistent organic pollutants. United Nations Environmental Programme, Suiza. ISTAS (2000). Disruptores endocrinos: Un Nuevo riesgo tóxico. http://www.redunidadesdeigualdad.udl.cat/fileadmin/Recursos/Salud/disruptoresendocrino s.pdf (Consultado en mayo de 2015). Jenner, M.G. (1979). Pseudohermaphroditism in Ilyanassa obsoleta. Science 205: 1407-1409. Jensen S. (1996). Report of a new chemical hazard. New Scientist 32: 612. Jensen S., Johnels A.G., Olsson M., Otterlind G. (1969). DDT and PCB in marine animals from Swedish waters. Nature 224: 247-250. Kimbrough R.D. (1987). Human health effects of polychlorinated biphenyls and polybrominated biphenyls. Annual Review of Pharmacology and Toxicology 27: 87-111. Kimbrough R.D. (1995). Polychlorinated biphenyls (PCBs) and human health: an update. Critical Reviews in Toxicology 25: 133-163. Kubiak T.J., Harris H.J., Smith L.M., Schwartz T.R., Stalling D.L., Trick J.A., Sileo L., Docherty D.E., Erdman T.C. (1989). Microcontaminants and reproductive impairment of the Foster ́s tern on Green Bay, Lake Michigan-1983. Archives of Environmental Contamination and Toxicology 18: 706-727. Lavado R., Thibaut R., Raldúa D., Martín R., Porte C. (2004). First evidence of endocrine disruption in feral carp from Ebro River. Toxicology and Applied Pharmacology 196: 247-257. Leonards P.E.G. (1997). PCBs in mustelids: Analysis, food chain transfer and critical levels. Dissertation. Free University of Amsterdam. MAGRAMA (Ministerio de Agricultura, Alimentación y Medio Ambiente)(2014).Contaminantes Orgánicos Persistentes: COPs. Enlace web: http://www.magrama.gob.es/es/calidad-y-evaluacion-ambiental/temas/productosquimicos/contaminantes-organicos-persistentes-cop/ (consultado en febrero 2015). Martin P.A., Mcdaniel T.V., Hunter B. (2006). Temporal and spatial trends in chlorinated hydrocarbon concentrations of mink in Canadian Lakes Erie and St. Clair. Environmental. Monitoring and Assessment 113: 245-263. MartineaU D., Lagace A., Béland P., Higgins R., Armstrong D., Shugart L.R. (1988). Pathology of stranded beluga whales (Delphinapterus leucas) from the St. Lawrence Estuary, Quebec, Canada. Journal of Comparative Pathology 98(3): 289-311. Mossner S., Ballschmiter K. (1997). Marine mammals as global pollution indicators for organochlorines. Chemosphere 34: 1285-1296. Muir D., Braune B., Demarch B., Norstrom R., Wagemann R., Lockhart L., Hargrave B., Bright D., Addison R., Payne J., Reimer K. (1999). Spatial and temporal trends and effects of contaminants in the Canadian Arctic marine ecosystem: a review. Science of the Total Environment 230: 83-144. Muir D., Koczanski K., Rosemberg B., Beland P. (1996). Persistent organochlorine in Beluga whales (Delphinapterus leucas) from the St Lawrence River Estuary-II. Temporal trends, 1982-1994. Environmental Pollution 93: 235-245. Muir D., Norstrom R.J. (2000). Geographical differences and time trends of persistent organic pollutants in the Arctic. Toxicology Letters 112-113: 93-101. Muir D., Wagemann R., Hargrave B.T., Thomas D.J., Peakall D.B., Norstrom R.J. (1992). Arctic marine ecosystem contamination. Science of the Total Environment 122: 75-134. Observatorio Medioambiental; Vol. 19 (2016); 91-109 1988-3277 1139-1987 Polychlorinated biphenyls; endocrine disruptor; wildlife Bifenilos policlorados; disruptor endocrino; fauna salvaje Biphényles polychlorés; disrupteur endocrinien; la faune info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Artículo revisado por pares 2016 ftunicmadridrev https://doi.org/10.5209/OBMD.54160 2019-06-15T07:07:22Z Los Bifenilos Policlorados son una amplia familia de contaminantes ambientales persistentes de enorme relevancia ambiental, pues a pesar de estar prohibidos, siguen encontrándose en concentraciones preocupantes en el medio ambiente, suficientes como para desencadenar programas de biomonitorizacion ambiental. Y en esta necesidad de seguir identificándolos y cuantificándolos se encuentra, en un punto destacado, su potencial efecto como disruptores endocrinos, tema de suma importancia desde el punto de vista de la reproducción de las especies de vida salvaje. De hecho, en las dos últimas décadas, se ha incrementado entre la comunidad científica el interés por investigar las posibles alteraciones en el funcionamiento del sistema endocrino de vertebrados e invertebrados como consecuencia de la exposición a productos químicos. En definitiva, la presente revisión resume los conocimientos más actualizados existentes sobre los Bifenilos policlorados cuantificados en la fauna salvaje, y sus principales efectos sobre la reproducción. Les biphényles polychlorés sont une grande famille de polluants environnementaux persistants d'une énorme importance pour l'environnement, parce que bien qu'ils soient interdits, on trouve encore des concentrations alarmantes dans l'environnement suffisant pour déclencher des programmes de biosurveillance de l'environnement. Et ce besoin de continuer à identifier et quantifier eux est, dans un point culminant son effet potentiel comme perturbateurs endocriniens, question importante du point de vue de la reproduction des espèces d'animaux sauvages. En fait, au cours des deux dernières décennies, il a augmenté dans l'intérêt de la communauté scientifique enquêter sur d'éventuelles modifications dans le fonctionnement du système endocrinien des vertébrés et des invertébrés à la suite de l'exposition aux produits chimiques. En bref, la présente revue résume les connaissances de la date actuelle sur les polychlorobiphényles quantifiés dans la faune sauvage, et leurs principaux effets sur la reproduction. Polychlorinated biphenyls are a broad family of persistent environmental pollutants of enormous environmental significance, because despite being prohibited, they are still found in alarming concentrations in the environment, enough to trigger environmental biomonitoring programs. Associated to this need to continue identifying and quantifying them, their potential effect as endocrine disruptors is of great relevance, being an important issue from the point of view of the reproduction of wildlife species. In fact, in the last two decades, the scientific community interest about investigating the alterations in the functioning of the endocrine system of vertebrates and invertebrates because of exposure to chemicals has increased. In short, the present review summarizes current date knowledge on polychlorinated biphenyls quantified in wildlife, and their main effects on reproduction. Article in Journal/Newspaper Arctic Polar Biology Universidad Complutense de Madrid (UCM): Revistas Científicas Complutenses Consecuencia ENVELOPE(-60.783,-60.783,-63.717,-63.717) Observatorio Medioambiental 19 91 109