Influence of feeding on metabolite excretion evidenced by urine 1H NMR spectral profiles: a comparison between subjects living in Rome and subjects living at arctic latitudes (Svalbard)

• Published in: Clinica Chimica Acta
• Main Authors: C. ZUPPI, F. FORNI, F. FERRARI, C. ROSSI, B. GIARDINA, MESSANA, IRENE
• Other Authors: C., Zuppi, Messana, Irene, F., Forni, F., Ferrari, C., Rossi, B., Giardina
• Format: Article in Journal/Newspaper
• Language: English
• Published: 1998
• Subjects: Svalbard
• Online Access: http://hdl.handle.net/11584/1436; https://doi.org/10.1016/S0009-8981(98)00132-6

Urines from 25 normal subjects living in Rome and 25 normal subjects living in Ny-Alesund (Svaldbard) were analysed by 1HNMR spectroscopy. The observed differences in the concentration of the major metabolites were correlated to the composition of the diet. It was found that a diet rich of carbohydrates, such as the Italian diet, is respondible for an increased excretion of citrate, lactate, alanine, and glycine.Thus a correct diagnostical interpretation of urinary metabolites needs to consider feeding habits.