A simple enzymatic preparation of 2',3'-di-O-acetylnucleosides through a lipase catalyzed alcoholysis

Several 2',3'-di-O-acetylnucleosides (2a-d) were obtained regioselectively through a Candida antarctica B lipase catalyzed alcoholysis.

Bibliographic Details
Main Authors: Zinni, A., Schmidt, A., Gallo, M., Iglesias, L., Iribarren, A.
Format: Journal/Newspaper
Language:unknown
Subjects:
2',3' di o acetylnucleoside derivative
nucleoside derivative
triacylglycerol lipase
unclassified drug
alcoholysis
Candida antarctica
catalysis
catalyst
conference paper
drug structure
drug synthesis
enzyme isolation
Antarc*
Antarctica
Online Access:https://hdl.handle.net/20.500.12110/paper_14203049_v5_n3_p533_Zinni
Description
Summary:Several 2',3'-di-O-acetylnucleosides (2a-d) were obtained regioselectively through a Candida antarctica B lipase catalyzed alcoholysis.

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