Illudalane sesquiterpenoids from the soft coral Alcyonium paessleri: The first natural nitrate esters
Fifteen illudalane sesquiterpenoids, alcyopterosins A-O (1-15) have been isolated from the subAntarctic soft coral Alcyonium paessleri which was collected at a depth of 200 m near the South Georgia Islands, and their structures were elucidated by spectroscopic techniques. Eight of these compounds (2...
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ftunibueairesbd:todo:paper_00223263_v65_n15_p4482_Palermo 2023-10-29T02:30:52+01:00 Illudalane sesquiterpenoids from the soft coral Alcyonium paessleri: The first natural nitrate esters Palermo, J.A. Brasco, M.F.R. Spagnuolo, C. Seldes, A.M. https://hdl.handle.net/20.500.12110/paper_00223263_v65_n15_p4482_Palermo unknown http://hdl.handle.net/20.500.12110/paper_00223263_v65_n15_p4482_Palermo info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar alcyopterosin A alcyopterosin C alcyopterosin E alcyopterosin H antineoplastic agent illudalane natural product nitric acid derivative sesquiterpenoid unclassified drug antineoplastic activity article cancer cell chemical bond controlled study coral drug cytotoxicity drug isolation drug structure human human cell marine environment nonhuman nuclear Overhauser effect proton nuclear magnetic resonance structure analysis Animals Antarctic Regions Cell Line Cnidaria Esters Humans Magnetic Resonance Spectroscopy Molecular Structure Nitrates Sesquiterpenes Spectroscopy Fourier Transform Infrared JOUR ftunibueairesbd https://doi.org/20.500.12110/paper_00223263_v65_n15_p4482_Palermo 2023-10-05T01:20:56Z Fifteen illudalane sesquiterpenoids, alcyopterosins A-O (1-15) have been isolated from the subAntarctic soft coral Alcyonium paessleri which was collected at a depth of 200 m near the South Georgia Islands, and their structures were elucidated by spectroscopic techniques. Eight of these compounds (2, 3, 5-8, 10, and 13) are the first natural nitrate esters, while the other four (1, 4, 11, and 12) are chlorinated. These compounds are as well the first illudalane sesquiterpenoids to be isolated from the marine environement. Compounds 1, 3, 5, and 8 showeld mild cytotoxicity toward human tumor cell lines. Fil:Palermo, J.A. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Spagnuolo, C. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Seldes, A.M. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Journal/Newspaper Antarc* Antarctic Biblioteca Digital FCEN-UBA (Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires) |
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Biblioteca Digital FCEN-UBA (Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires) |
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ftunibueairesbd |
language |
unknown |
topic |
alcyopterosin A alcyopterosin C alcyopterosin E alcyopterosin H antineoplastic agent illudalane natural product nitric acid derivative sesquiterpenoid unclassified drug antineoplastic activity article cancer cell chemical bond controlled study coral drug cytotoxicity drug isolation drug structure human human cell marine environment nonhuman nuclear Overhauser effect proton nuclear magnetic resonance structure analysis Animals Antarctic Regions Cell Line Cnidaria Esters Humans Magnetic Resonance Spectroscopy Molecular Structure Nitrates Sesquiterpenes Spectroscopy Fourier Transform Infrared |
spellingShingle |
alcyopterosin A alcyopterosin C alcyopterosin E alcyopterosin H antineoplastic agent illudalane natural product nitric acid derivative sesquiterpenoid unclassified drug antineoplastic activity article cancer cell chemical bond controlled study coral drug cytotoxicity drug isolation drug structure human human cell marine environment nonhuman nuclear Overhauser effect proton nuclear magnetic resonance structure analysis Animals Antarctic Regions Cell Line Cnidaria Esters Humans Magnetic Resonance Spectroscopy Molecular Structure Nitrates Sesquiterpenes Spectroscopy Fourier Transform Infrared Palermo, J.A. Brasco, M.F.R. Spagnuolo, C. Seldes, A.M. Illudalane sesquiterpenoids from the soft coral Alcyonium paessleri: The first natural nitrate esters |
topic_facet |
alcyopterosin A alcyopterosin C alcyopterosin E alcyopterosin H antineoplastic agent illudalane natural product nitric acid derivative sesquiterpenoid unclassified drug antineoplastic activity article cancer cell chemical bond controlled study coral drug cytotoxicity drug isolation drug structure human human cell marine environment nonhuman nuclear Overhauser effect proton nuclear magnetic resonance structure analysis Animals Antarctic Regions Cell Line Cnidaria Esters Humans Magnetic Resonance Spectroscopy Molecular Structure Nitrates Sesquiterpenes Spectroscopy Fourier Transform Infrared |
description |
Fifteen illudalane sesquiterpenoids, alcyopterosins A-O (1-15) have been isolated from the subAntarctic soft coral Alcyonium paessleri which was collected at a depth of 200 m near the South Georgia Islands, and their structures were elucidated by spectroscopic techniques. Eight of these compounds (2, 3, 5-8, 10, and 13) are the first natural nitrate esters, while the other four (1, 4, 11, and 12) are chlorinated. These compounds are as well the first illudalane sesquiterpenoids to be isolated from the marine environement. Compounds 1, 3, 5, and 8 showeld mild cytotoxicity toward human tumor cell lines. Fil:Palermo, J.A. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Spagnuolo, C. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Seldes, A.M. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. |
format |
Journal/Newspaper |
author |
Palermo, J.A. Brasco, M.F.R. Spagnuolo, C. Seldes, A.M. |
author_facet |
Palermo, J.A. Brasco, M.F.R. Spagnuolo, C. Seldes, A.M. |
author_sort |
Palermo, J.A. |
title |
Illudalane sesquiterpenoids from the soft coral Alcyonium paessleri: The first natural nitrate esters |
title_short |
Illudalane sesquiterpenoids from the soft coral Alcyonium paessleri: The first natural nitrate esters |
title_full |
Illudalane sesquiterpenoids from the soft coral Alcyonium paessleri: The first natural nitrate esters |
title_fullStr |
Illudalane sesquiterpenoids from the soft coral Alcyonium paessleri: The first natural nitrate esters |
title_full_unstemmed |
Illudalane sesquiterpenoids from the soft coral Alcyonium paessleri: The first natural nitrate esters |
title_sort |
illudalane sesquiterpenoids from the soft coral alcyonium paessleri: the first natural nitrate esters |
url |
https://hdl.handle.net/20.500.12110/paper_00223263_v65_n15_p4482_Palermo |
genre |
Antarc* Antarctic |
genre_facet |
Antarc* Antarctic |
op_relation |
http://hdl.handle.net/20.500.12110/paper_00223263_v65_n15_p4482_Palermo |
op_rights |
info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar |
op_doi |
https://doi.org/20.500.12110/paper_00223263_v65_n15_p4482_Palermo |
_version_ |
1781063163007991808 |