Chemoenzymatic synthesis of novel N-(2-hydroxyethyl)-β-peptoid oligomer derivatives and application to porous polycaprolactone films
The biocatalytic synthesis of a novel peptoid oligomer is reported. The oligomer is acetylated and a copolymer with polycaprolactone is prepared. These derivatives are employed for the preparation of nanoporous films. Poly[N-(2-hydroxyethyl)-β-propylamide] oligomer is synthesized using a simple enzy...
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ftunibueairesbd:paper:paper_09598103_v_n_p_Monsalve 2023-05-15T13:50:11+02:00 Chemoenzymatic synthesis of novel N-(2-hydroxyethyl)-β-peptoid oligomer derivatives and application to porous polycaprolactone films Monsalve, Leandro Nicolás Baldessari, Alicia 2013 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_09598103_v_n_p_Monsalve https://hdl.handle.net/20.500.12110/paper_09598103_v_n_p_Monsalve unknown https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_09598103_v_n_p_Monsalve http://hdl.handle.net/20.500.12110/paper_09598103_v_n_p_Monsalve β-peptoid Films Lipase Polycaprolactone Surface properties 2013 ftunibueairesbd https://doi.org/20.500.12110/paper_09598103_v_n_p_Monsalve 2023-02-16T02:27:50Z The biocatalytic synthesis of a novel peptoid oligomer is reported. The oligomer is acetylated and a copolymer with polycaprolactone is prepared. These derivatives are employed for the preparation of nanoporous films. Poly[N-(2-hydroxyethyl)-β-propylamide] oligomer is synthesized using a simple enzymatic procedure involving Candida antarctica lipase B. This novel compound is obtained by a green and chemoselective method from economic reactants in good yield. The β-peptoid oligomer is characterized by spectroscopic methods showing low molecular weight and low dispersity. Two derivatives of the β-peptoid oligomer are prepared by acetylation and by grafting polycaprolactone by ring opening polymerization from the pendant hydroxyl groups. These products are blended with polycaprolactone to make films by solvent casting. The inclusion of the acyl derivatives of the β-peptoid to polycaprolactone affects the morphology of the film yielding microstructured and nanostructured patterns. © 2013 Society of Chemical Industry. Fil:Monsalve, L.N. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Baldessari, A. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Other/Unknown Material Antarc* Antarctica Biblioteca Digital FCEN-UBA (Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires) Argentina |
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Open Polar |
collection |
Biblioteca Digital FCEN-UBA (Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires) |
op_collection_id |
ftunibueairesbd |
language |
unknown |
topic |
β-peptoid Films Lipase Polycaprolactone Surface properties |
spellingShingle |
β-peptoid Films Lipase Polycaprolactone Surface properties Monsalve, Leandro Nicolás Baldessari, Alicia Chemoenzymatic synthesis of novel N-(2-hydroxyethyl)-β-peptoid oligomer derivatives and application to porous polycaprolactone films |
topic_facet |
β-peptoid Films Lipase Polycaprolactone Surface properties |
description |
The biocatalytic synthesis of a novel peptoid oligomer is reported. The oligomer is acetylated and a copolymer with polycaprolactone is prepared. These derivatives are employed for the preparation of nanoporous films. Poly[N-(2-hydroxyethyl)-β-propylamide] oligomer is synthesized using a simple enzymatic procedure involving Candida antarctica lipase B. This novel compound is obtained by a green and chemoselective method from economic reactants in good yield. The β-peptoid oligomer is characterized by spectroscopic methods showing low molecular weight and low dispersity. Two derivatives of the β-peptoid oligomer are prepared by acetylation and by grafting polycaprolactone by ring opening polymerization from the pendant hydroxyl groups. These products are blended with polycaprolactone to make films by solvent casting. The inclusion of the acyl derivatives of the β-peptoid to polycaprolactone affects the morphology of the film yielding microstructured and nanostructured patterns. © 2013 Society of Chemical Industry. Fil:Monsalve, L.N. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Baldessari, A. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. |
author |
Monsalve, Leandro Nicolás Baldessari, Alicia |
author_facet |
Monsalve, Leandro Nicolás Baldessari, Alicia |
author_sort |
Monsalve, Leandro Nicolás |
title |
Chemoenzymatic synthesis of novel N-(2-hydroxyethyl)-β-peptoid oligomer derivatives and application to porous polycaprolactone films |
title_short |
Chemoenzymatic synthesis of novel N-(2-hydroxyethyl)-β-peptoid oligomer derivatives and application to porous polycaprolactone films |
title_full |
Chemoenzymatic synthesis of novel N-(2-hydroxyethyl)-β-peptoid oligomer derivatives and application to porous polycaprolactone films |
title_fullStr |
Chemoenzymatic synthesis of novel N-(2-hydroxyethyl)-β-peptoid oligomer derivatives and application to porous polycaprolactone films |
title_full_unstemmed |
Chemoenzymatic synthesis of novel N-(2-hydroxyethyl)-β-peptoid oligomer derivatives and application to porous polycaprolactone films |
title_sort |
chemoenzymatic synthesis of novel n-(2-hydroxyethyl)-β-peptoid oligomer derivatives and application to porous polycaprolactone films |
publishDate |
2013 |
url |
https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_09598103_v_n_p_Monsalve https://hdl.handle.net/20.500.12110/paper_09598103_v_n_p_Monsalve |
geographic |
Argentina |
geographic_facet |
Argentina |
genre |
Antarc* Antarctica |
genre_facet |
Antarc* Antarctica |
op_relation |
https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_09598103_v_n_p_Monsalve http://hdl.handle.net/20.500.12110/paper_09598103_v_n_p_Monsalve |
op_doi |
https://doi.org/20.500.12110/paper_09598103_v_n_p_Monsalve |
_version_ |
1766253186439446528 |