Safety Factors in Pesticide Risk Assessment:Differences in Species Sensitivity and Acute-Chronic Relations

• Main Authors: Elmegaard, N., Jagers op Akkerhuis, G. A. J. M.
• Format: Book
• Language: English
• Published: National Environmental Research Institute 2000
• Subjects: National Environmental Research Institute
• Online Access: https://pure.au.dk/portal/da/publications/safety-factors-in-pesticide-risk-assessment(f74030c0-7e9c-11dd-a5a8-000ea68e967b).html; http://www.dmu.dk/1_viden/2_Publikationer/3_fagrapporter/default.asp

Foreword It has become common practice to protect the environment from hazardous chemicals by use of risk assessment to establish environmental concentration at which only limited damage to the ecosystem can be expected. The methods and tools applied in the risk assessment need constant evaluation to secure that the methodology is adequate. As new knowledge surfaces the risk assessment procedures develops. The present report is a contribution to the development of safety factors used to account for the uncertainty when · extrapolating from the results of test with a single species in the laboratory to many species in real ecosystems · extrapolating from acute to chronic or long term effects. The project was co-funded by the Environmental Protection Agency and The National Environmental Research Institute Summary In this report two factors are studied which have implications for the size of safety factors used in pesticide risk assessment: the variability in species sensitivities, and the relationship between acute LC50's and chronic NOEC's.