Level and Temporal Trend of Perfluoroalkyl Acids in Greenlandic Inuit
Objectives: Perfluoroalkyl acids (PFAAs) have been detected in human blood, breast milk and umbilical cord blood across the globe. PFAAs do accumulate in the marine food chain in Arctic regions. In Greenland, increasing PFAA concentrations were observed during 19822006 in ringed seals and polar bear...
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ftuniaarhuspubl:oai:pure.atira.dk:publications/e6b9d692-da7c-4b2e-bbfc-ef36e939e13d 2023-05-15T14:24:55+02:00 Level and Temporal Trend of Perfluoroalkyl Acids in Greenlandic Inuit Long, Manhai Bossi, Rossana Bonefeld-Jørgensen, Eva Cecilie 2011-12 https://pure.au.dk/portal/da/publications/level-and-temporal-trend-of-perfluoroalkyl-acids-in-greenlandic-inuit(e6b9d692-da7c-4b2e-bbfc-ef36e939e13d).html eng eng info:eu-repo/semantics/restrictedAccess Long , M , Bossi , R & Bonefeld-Jørgensen , E C 2011 , ' Level and Temporal Trend of Perfluoroalkyl Acids in Greenlandic Inuit ' , Paper presented at AMAP (The Arctic as a Messenger for Global Processes - Climate Change and Pollution) , Copenhagen , Denmark , 03/05/2011 - 06/05/2011 . conferenceObject 2011 ftuniaarhuspubl 2020-07-18T21:16:37Z Objectives: Perfluoroalkyl acids (PFAAs) have been detected in human blood, breast milk and umbilical cord blood across the globe. PFAAs do accumulate in the marine food chain in Arctic regions. In Greenland, increasing PFAA concentrations were observed during 19822006 in ringed seals and polar bears. However, until now, no data have been reported for PFAAs in Greenlandic Inuit. This study assesses the level and temporal trend of serum PFAAs in Greenlandic Inuit. Study design: Cross-section and temporal time trend survey. Methods: Serum PFAA levels were determined in 284 Inuit from different Greenlandic districts using liquid chromatography-tandem mass spectrometry with electrospray ionization. The temporal time trend of serum PFAAs in Nuuk Inuit during 19982005 and the correlation between serum PFAAs and legacy persistent organic pollutants (POPs) were explored. Results: Serum PFAA levels were higher in Nuuk Inuit than in non-Nuuk Inuit. Within the same district, higher PFAA levels were observed for males. An age-dependent, increasing trend of serum PFAA levels in the period from 19982005 was observed for Nuuk Inuit. For the pooled gender data, no significant association between PFAAs and legacy POPs was observed for Nuuk Inuit while for non-Nuuk Inuit this correlation was significant. No correlation between PFAAs and legacy POPs was found for male Inuit, whereas significant correlation was observed both for pooled female Inuit and for non-Nuuk Inuit females. Conclusions: We suggest that sources other than seafood intake might contribute to the observed higher PFAA levels in Nuuk Inuit compared to the pooled non-Nuuk Inuit. Conference Object Arctic Arctic Greenland greenlandic inuit Nuuk Aarhus University: Research Arctic Greenland Nuuk ENVELOPE(-52.150,-52.150,68.717,68.717) |
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Aarhus University: Research |
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ftuniaarhuspubl |
language |
English |
description |
Objectives: Perfluoroalkyl acids (PFAAs) have been detected in human blood, breast milk and umbilical cord blood across the globe. PFAAs do accumulate in the marine food chain in Arctic regions. In Greenland, increasing PFAA concentrations were observed during 19822006 in ringed seals and polar bears. However, until now, no data have been reported for PFAAs in Greenlandic Inuit. This study assesses the level and temporal trend of serum PFAAs in Greenlandic Inuit. Study design: Cross-section and temporal time trend survey. Methods: Serum PFAA levels were determined in 284 Inuit from different Greenlandic districts using liquid chromatography-tandem mass spectrometry with electrospray ionization. The temporal time trend of serum PFAAs in Nuuk Inuit during 19982005 and the correlation between serum PFAAs and legacy persistent organic pollutants (POPs) were explored. Results: Serum PFAA levels were higher in Nuuk Inuit than in non-Nuuk Inuit. Within the same district, higher PFAA levels were observed for males. An age-dependent, increasing trend of serum PFAA levels in the period from 19982005 was observed for Nuuk Inuit. For the pooled gender data, no significant association between PFAAs and legacy POPs was observed for Nuuk Inuit while for non-Nuuk Inuit this correlation was significant. No correlation between PFAAs and legacy POPs was found for male Inuit, whereas significant correlation was observed both for pooled female Inuit and for non-Nuuk Inuit females. Conclusions: We suggest that sources other than seafood intake might contribute to the observed higher PFAA levels in Nuuk Inuit compared to the pooled non-Nuuk Inuit. |
format |
Conference Object |
author |
Long, Manhai Bossi, Rossana Bonefeld-Jørgensen, Eva Cecilie |
spellingShingle |
Long, Manhai Bossi, Rossana Bonefeld-Jørgensen, Eva Cecilie Level and Temporal Trend of Perfluoroalkyl Acids in Greenlandic Inuit |
author_facet |
Long, Manhai Bossi, Rossana Bonefeld-Jørgensen, Eva Cecilie |
author_sort |
Long, Manhai |
title |
Level and Temporal Trend of Perfluoroalkyl Acids in Greenlandic Inuit |
title_short |
Level and Temporal Trend of Perfluoroalkyl Acids in Greenlandic Inuit |
title_full |
Level and Temporal Trend of Perfluoroalkyl Acids in Greenlandic Inuit |
title_fullStr |
Level and Temporal Trend of Perfluoroalkyl Acids in Greenlandic Inuit |
title_full_unstemmed |
Level and Temporal Trend of Perfluoroalkyl Acids in Greenlandic Inuit |
title_sort |
level and temporal trend of perfluoroalkyl acids in greenlandic inuit |
publishDate |
2011 |
url |
https://pure.au.dk/portal/da/publications/level-and-temporal-trend-of-perfluoroalkyl-acids-in-greenlandic-inuit(e6b9d692-da7c-4b2e-bbfc-ef36e939e13d).html |
long_lat |
ENVELOPE(-52.150,-52.150,68.717,68.717) |
geographic |
Arctic Greenland Nuuk |
geographic_facet |
Arctic Greenland Nuuk |
genre |
Arctic Arctic Greenland greenlandic inuit Nuuk |
genre_facet |
Arctic Arctic Greenland greenlandic inuit Nuuk |
op_source |
Long , M , Bossi , R & Bonefeld-Jørgensen , E C 2011 , ' Level and Temporal Trend of Perfluoroalkyl Acids in Greenlandic Inuit ' , Paper presented at AMAP (The Arctic as a Messenger for Global Processes - Climate Change and Pollution) , Copenhagen , Denmark , 03/05/2011 - 06/05/2011 . |
op_rights |
info:eu-repo/semantics/restrictedAccess |
_version_ |
1766297360539844608 |