Exposure to Polybrominated Diphenyl Ethers and Male Reproductive Function in Greenland, Poland and Ukraine
Animal and a few human studies suggest that polybrominated diphenyl ethers (PBDEs) may affect male reproductive function. The aim of the present study was to evaluate if male reproductive function was associated with serum level of PBDEs. We evaluated, in a cross-sectional study, the effects of envi...
Published in: | Reproductive Toxicology |
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Format: | Article in Journal/Newspaper |
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2013
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Online Access: | https://pure.au.dk/portal/da/publications/exposure-to-polybrominated-diphenyl-ethers-and-male-reproductive-function-in-greenland-poland-and-ukraine(e38fc9a7-4883-42ec-920e-2254c4c863fc).html https://doi.org/10.1016/j.reprotox.2013.10.002 |
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ftuniaarhuspubl:oai:pure.atira.dk:publications/e38fc9a7-4883-42ec-920e-2254c4c863fc 2023-12-10T09:45:45+01:00 Exposure to Polybrominated Diphenyl Ethers and Male Reproductive Function in Greenland, Poland and Ukraine Toft, Gunnar Lenters, Virissa Vermeulen, Roel Heederik, Dick Thomsen, Cathrine Becher, Georg Giwercman, Aleksander Bizzaro, Davide Manicardi, Gian Carlo Spanò, Marcello Rylander, Lars Pedersen, Henning S Struciński, Paweł Zviezdai, Valentyna Bonde, Jens Peter 2013-10-26 https://pure.au.dk/portal/da/publications/exposure-to-polybrominated-diphenyl-ethers-and-male-reproductive-function-in-greenland-poland-and-ukraine(e38fc9a7-4883-42ec-920e-2254c4c863fc).html https://doi.org/10.1016/j.reprotox.2013.10.002 eng eng https://pure.au.dk/portal/da/publications/exposure-to-polybrominated-diphenyl-ethers-and-male-reproductive-function-in-greenland-poland-and-ukraine(e38fc9a7-4883-42ec-920e-2254c4c863fc).html info:eu-repo/semantics/restrictedAccess Toft , G , Lenters , V , Vermeulen , R , Heederik , D , Thomsen , C , Becher , G , Giwercman , A , Bizzaro , D , Manicardi , G C , Spanò , M , Rylander , L , Pedersen , H S , Struciński , P , Zviezdai , V & Bonde , J P 2013 , ' Exposure to Polybrominated Diphenyl Ethers and Male Reproductive Function in Greenland, Poland and Ukraine ' , Reproductive toxicology (Elmsford, N.Y.) . https://doi.org/10.1016/j.reprotox.2013.10.002 article 2013 ftuniaarhuspubl https://doi.org/10.1016/j.reprotox.2013.10.002 2023-11-15T23:58:49Z Animal and a few human studies suggest that polybrominated diphenyl ethers (PBDEs) may affect male reproductive function. The aim of the present study was to evaluate if male reproductive function was associated with serum level of PBDEs. We evaluated, in a cross-sectional study, the effects of environmental exposure to BDE-47 and BDE-153 on reproductive hormones and semen quality, including markers of DNA damage and apoptosis, in 299 spouses of pregnant women from Greenland, Poland and Ukraine. Adjusted linear regression models indicated no strong associations between BDE-47 or BDE-153 exposure and markers of male semen quality or reproductive hormones. In the largest study to date we demonstrate that BDE-47 and BDE-153 exposure was not associated with altered semen characteristics or reproductive hormones, indicating that male reproductive function is not affected by the exposure level of these compounds in fertile European or Arctic populations. Article in Journal/Newspaper Arctic Greenland Aarhus University: Research Arctic Greenland Reproductive Toxicology 43 1 7 |
institution |
Open Polar |
collection |
Aarhus University: Research |
op_collection_id |
ftuniaarhuspubl |
language |
English |
description |
Animal and a few human studies suggest that polybrominated diphenyl ethers (PBDEs) may affect male reproductive function. The aim of the present study was to evaluate if male reproductive function was associated with serum level of PBDEs. We evaluated, in a cross-sectional study, the effects of environmental exposure to BDE-47 and BDE-153 on reproductive hormones and semen quality, including markers of DNA damage and apoptosis, in 299 spouses of pregnant women from Greenland, Poland and Ukraine. Adjusted linear regression models indicated no strong associations between BDE-47 or BDE-153 exposure and markers of male semen quality or reproductive hormones. In the largest study to date we demonstrate that BDE-47 and BDE-153 exposure was not associated with altered semen characteristics or reproductive hormones, indicating that male reproductive function is not affected by the exposure level of these compounds in fertile European or Arctic populations. |
format |
Article in Journal/Newspaper |
author |
Toft, Gunnar Lenters, Virissa Vermeulen, Roel Heederik, Dick Thomsen, Cathrine Becher, Georg Giwercman, Aleksander Bizzaro, Davide Manicardi, Gian Carlo Spanò, Marcello Rylander, Lars Pedersen, Henning S Struciński, Paweł Zviezdai, Valentyna Bonde, Jens Peter |
spellingShingle |
Toft, Gunnar Lenters, Virissa Vermeulen, Roel Heederik, Dick Thomsen, Cathrine Becher, Georg Giwercman, Aleksander Bizzaro, Davide Manicardi, Gian Carlo Spanò, Marcello Rylander, Lars Pedersen, Henning S Struciński, Paweł Zviezdai, Valentyna Bonde, Jens Peter Exposure to Polybrominated Diphenyl Ethers and Male Reproductive Function in Greenland, Poland and Ukraine |
author_facet |
Toft, Gunnar Lenters, Virissa Vermeulen, Roel Heederik, Dick Thomsen, Cathrine Becher, Georg Giwercman, Aleksander Bizzaro, Davide Manicardi, Gian Carlo Spanò, Marcello Rylander, Lars Pedersen, Henning S Struciński, Paweł Zviezdai, Valentyna Bonde, Jens Peter |
author_sort |
Toft, Gunnar |
title |
Exposure to Polybrominated Diphenyl Ethers and Male Reproductive Function in Greenland, Poland and Ukraine |
title_short |
Exposure to Polybrominated Diphenyl Ethers and Male Reproductive Function in Greenland, Poland and Ukraine |
title_full |
Exposure to Polybrominated Diphenyl Ethers and Male Reproductive Function in Greenland, Poland and Ukraine |
title_fullStr |
Exposure to Polybrominated Diphenyl Ethers and Male Reproductive Function in Greenland, Poland and Ukraine |
title_full_unstemmed |
Exposure to Polybrominated Diphenyl Ethers and Male Reproductive Function in Greenland, Poland and Ukraine |
title_sort |
exposure to polybrominated diphenyl ethers and male reproductive function in greenland, poland and ukraine |
publishDate |
2013 |
url |
https://pure.au.dk/portal/da/publications/exposure-to-polybrominated-diphenyl-ethers-and-male-reproductive-function-in-greenland-poland-and-ukraine(e38fc9a7-4883-42ec-920e-2254c4c863fc).html https://doi.org/10.1016/j.reprotox.2013.10.002 |
geographic |
Arctic Greenland |
geographic_facet |
Arctic Greenland |
genre |
Arctic Greenland |
genre_facet |
Arctic Greenland |
op_source |
Toft , G , Lenters , V , Vermeulen , R , Heederik , D , Thomsen , C , Becher , G , Giwercman , A , Bizzaro , D , Manicardi , G C , Spanò , M , Rylander , L , Pedersen , H S , Struciński , P , Zviezdai , V & Bonde , J P 2013 , ' Exposure to Polybrominated Diphenyl Ethers and Male Reproductive Function in Greenland, Poland and Ukraine ' , Reproductive toxicology (Elmsford, N.Y.) . https://doi.org/10.1016/j.reprotox.2013.10.002 |
op_relation |
https://pure.au.dk/portal/da/publications/exposure-to-polybrominated-diphenyl-ethers-and-male-reproductive-function-in-greenland-poland-and-ukraine(e38fc9a7-4883-42ec-920e-2254c4c863fc).html |
op_rights |
info:eu-repo/semantics/restrictedAccess |
op_doi |
https://doi.org/10.1016/j.reprotox.2013.10.002 |
container_title |
Reproductive Toxicology |
container_volume |
43 |
container_start_page |
1 |
op_container_end_page |
7 |
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