Frequent left ventricular hypertrophy independent of blood pressure in 1851 pre-western Inuit

BACKGROUND: Elevated blood pressure is a risk factor for cardiovascular disease and may be detected by left ventricular hypertrophy (LVH) in electrocardiogram (ECG). Pre-western Inuit had frequent signs of LVH in ECG predominantly in the 3rd decade while a low occurrence of ischemic heart disease. M...

Full description

Bibliographic Details
Published in:Atherosclerosis
Main Authors: Andersen, Stig, Kjærgaard, Marie, Jørgensen, Marit Eika, Mulvad, Gert, Kjærgaard, Jens Jørgen
Format: Article in Journal/Newspaper
Language:English
Published: 2011
Subjects:
Online Access:https://pure.au.dk/portal/da/publications/frequent-left-ventricular-hypertrophy-independent-of-blood-pressure-in-1851-prewestern-inuit(db7483f1-8f29-42cc-b627-50675a984705).html
https://doi.org/10.1016/j.atherosclerosis.2011.02.034
Description
Summary:BACKGROUND: Elevated blood pressure is a risk factor for cardiovascular disease and may be detected by left ventricular hypertrophy (LVH) in electrocardiogram (ECG). Pre-western Inuit had frequent signs of LVH in ECG predominantly in the 3rd decade while a low occurrence of ischemic heart disease. METHODS: We evaluated the association between blood pressures and ECG signs of LVH, cardiac auscultation, and symptoms related to heart disease in the recently recovered data from the survey of 1851 Inuit conducted in 1962-1964 in East Greenland. RESULTS: The participation rate was 97%. Among the 812 Inuit aged 18years or above blood pressure was unaltered until the age of 39years (systolic, p=76; diastolic, p=0.36) and increased subsequently (both, p140mmHg was more frequent when aged >40years (p90mmHg was more common in men (p40years (p