Microevolution in time and space:SNP analysis of historical DNA reveals dynamic signatures of selection in Atlantic cod
Little is known about how quickly natural populations adapt to changes in their environment and how temporal and spatial variation in selection pressures interact to shape patterns of genetic diversity. We here address these issues with a series of genome scans in four overfished populations of Atla...
Published in: | Molecular Ecology |
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Language: | English |
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2013
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Online Access: | https://pure.au.dk/portal/da/publications/microevolution-in-time-and-space(b0e0ef9e-3d38-451b-a68e-8f04ee6c5806).html https://doi.org/10.1111/mec.12260 |
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ftuniaarhuspubl:oai:pure.atira.dk:publications/b0e0ef9e-3d38-451b-a68e-8f04ee6c5806 2023-12-17T10:27:02+01:00 Microevolution in time and space:SNP analysis of historical DNA reveals dynamic signatures of selection in Atlantic cod Therkildsen, Nina O. Hemmer-Hansen, Jakob Als, Thomas Damm Swain, Douglas P. Morgan, M. Joanne Trippel, Edward A. Palumbi, Stephen R. Meldrup, Dorte Nielsen, Einar E. 2013-05 https://pure.au.dk/portal/da/publications/microevolution-in-time-and-space(b0e0ef9e-3d38-451b-a68e-8f04ee6c5806).html https://doi.org/10.1111/mec.12260 eng eng https://pure.au.dk/portal/da/publications/microevolution-in-time-and-space(b0e0ef9e-3d38-451b-a68e-8f04ee6c5806).html info:eu-repo/semantics/restrictedAccess Therkildsen , N O , Hemmer-Hansen , J , Als , T D , Swain , D P , Morgan , M J , Trippel , E A , Palumbi , S R , Meldrup , D & Nielsen , E E 2013 , ' Microevolution in time and space : SNP analysis of historical DNA reveals dynamic signatures of selection in Atlantic cod ' , Molecular Ecology , vol. 22 , no. 9 , pp. 2424-2440 . https://doi.org/10.1111/mec.12260 fisheries-induced evolution Gadus morhua genome scan historical DNA selection temporal GADUS-MORHUA DIRECTIONAL SELECTION POPULATION-STRUCTURE GENETIC-VARIATION CLIMATE-CHANGE ST-LAWRENCE PHENOTYPIC SELECTION COMPUTER-PROGRAM MIGRATION RATES article 2013 ftuniaarhuspubl https://doi.org/10.1111/mec.12260 2023-11-22T23:59:15Z Little is known about how quickly natural populations adapt to changes in their environment and how temporal and spatial variation in selection pressures interact to shape patterns of genetic diversity. We here address these issues with a series of genome scans in four overfished populations of Atlantic cod (Gadus morhua) studied over an 80-year period. Screening of >1000 gene-associated single-nucleotide polymorphisms (SNPs) identified 77 loci that showed highly elevated levels of differentiation, likely as an effect of directional selection, in either time, space or both. Exploratory analysis suggested that temporal allele frequency shifts at certain loci may correlate with local temperature variation and with life history changes suggested to be fisheries induced. Interestingly, however, largely nonoverlapping sets of loci were temporal outliers in the different populations and outliers from the 1928 to 1960 period showed almost complete stability during later decades. The contrasting microevolutionary trajectories among populations resulted in sequential shifts in spatial outliers, with no locus maintaining elevated spatial differentiation throughout the study period. Simulations of migration coupled with observations of temporally stable spatial structure at neutral loci suggest that population replacement or gene flow alone could not explain all the observed allele frequency variation. Thus, the genetic changes are likely to at least partly be driven by highly dynamic temporally and spatially varying selection. These findings have important implications for our understanding of local adaptation and evolutionary potential in high gene flow organisms and underscore the need to carefully consider all dimensions of biocomplexity for evolutionarily sustainable management. Article in Journal/Newspaper atlantic cod Gadus morhua Aarhus University: Research Molecular Ecology 22 9 2424 2440 |
institution |
Open Polar |
collection |
Aarhus University: Research |
op_collection_id |
ftuniaarhuspubl |
language |
English |
topic |
fisheries-induced evolution Gadus morhua genome scan historical DNA selection temporal GADUS-MORHUA DIRECTIONAL SELECTION POPULATION-STRUCTURE GENETIC-VARIATION CLIMATE-CHANGE ST-LAWRENCE PHENOTYPIC SELECTION COMPUTER-PROGRAM MIGRATION RATES |
spellingShingle |
fisheries-induced evolution Gadus morhua genome scan historical DNA selection temporal GADUS-MORHUA DIRECTIONAL SELECTION POPULATION-STRUCTURE GENETIC-VARIATION CLIMATE-CHANGE ST-LAWRENCE PHENOTYPIC SELECTION COMPUTER-PROGRAM MIGRATION RATES Therkildsen, Nina O. Hemmer-Hansen, Jakob Als, Thomas Damm Swain, Douglas P. Morgan, M. Joanne Trippel, Edward A. Palumbi, Stephen R. Meldrup, Dorte Nielsen, Einar E. Microevolution in time and space:SNP analysis of historical DNA reveals dynamic signatures of selection in Atlantic cod |
topic_facet |
fisheries-induced evolution Gadus morhua genome scan historical DNA selection temporal GADUS-MORHUA DIRECTIONAL SELECTION POPULATION-STRUCTURE GENETIC-VARIATION CLIMATE-CHANGE ST-LAWRENCE PHENOTYPIC SELECTION COMPUTER-PROGRAM MIGRATION RATES |
description |
Little is known about how quickly natural populations adapt to changes in their environment and how temporal and spatial variation in selection pressures interact to shape patterns of genetic diversity. We here address these issues with a series of genome scans in four overfished populations of Atlantic cod (Gadus morhua) studied over an 80-year period. Screening of >1000 gene-associated single-nucleotide polymorphisms (SNPs) identified 77 loci that showed highly elevated levels of differentiation, likely as an effect of directional selection, in either time, space or both. Exploratory analysis suggested that temporal allele frequency shifts at certain loci may correlate with local temperature variation and with life history changes suggested to be fisheries induced. Interestingly, however, largely nonoverlapping sets of loci were temporal outliers in the different populations and outliers from the 1928 to 1960 period showed almost complete stability during later decades. The contrasting microevolutionary trajectories among populations resulted in sequential shifts in spatial outliers, with no locus maintaining elevated spatial differentiation throughout the study period. Simulations of migration coupled with observations of temporally stable spatial structure at neutral loci suggest that population replacement or gene flow alone could not explain all the observed allele frequency variation. Thus, the genetic changes are likely to at least partly be driven by highly dynamic temporally and spatially varying selection. These findings have important implications for our understanding of local adaptation and evolutionary potential in high gene flow organisms and underscore the need to carefully consider all dimensions of biocomplexity for evolutionarily sustainable management. |
format |
Article in Journal/Newspaper |
author |
Therkildsen, Nina O. Hemmer-Hansen, Jakob Als, Thomas Damm Swain, Douglas P. Morgan, M. Joanne Trippel, Edward A. Palumbi, Stephen R. Meldrup, Dorte Nielsen, Einar E. |
author_facet |
Therkildsen, Nina O. Hemmer-Hansen, Jakob Als, Thomas Damm Swain, Douglas P. Morgan, M. Joanne Trippel, Edward A. Palumbi, Stephen R. Meldrup, Dorte Nielsen, Einar E. |
author_sort |
Therkildsen, Nina O. |
title |
Microevolution in time and space:SNP analysis of historical DNA reveals dynamic signatures of selection in Atlantic cod |
title_short |
Microevolution in time and space:SNP analysis of historical DNA reveals dynamic signatures of selection in Atlantic cod |
title_full |
Microevolution in time and space:SNP analysis of historical DNA reveals dynamic signatures of selection in Atlantic cod |
title_fullStr |
Microevolution in time and space:SNP analysis of historical DNA reveals dynamic signatures of selection in Atlantic cod |
title_full_unstemmed |
Microevolution in time and space:SNP analysis of historical DNA reveals dynamic signatures of selection in Atlantic cod |
title_sort |
microevolution in time and space:snp analysis of historical dna reveals dynamic signatures of selection in atlantic cod |
publishDate |
2013 |
url |
https://pure.au.dk/portal/da/publications/microevolution-in-time-and-space(b0e0ef9e-3d38-451b-a68e-8f04ee6c5806).html https://doi.org/10.1111/mec.12260 |
genre |
atlantic cod Gadus morhua |
genre_facet |
atlantic cod Gadus morhua |
op_source |
Therkildsen , N O , Hemmer-Hansen , J , Als , T D , Swain , D P , Morgan , M J , Trippel , E A , Palumbi , S R , Meldrup , D & Nielsen , E E 2013 , ' Microevolution in time and space : SNP analysis of historical DNA reveals dynamic signatures of selection in Atlantic cod ' , Molecular Ecology , vol. 22 , no. 9 , pp. 2424-2440 . https://doi.org/10.1111/mec.12260 |
op_relation |
https://pure.au.dk/portal/da/publications/microevolution-in-time-and-space(b0e0ef9e-3d38-451b-a68e-8f04ee6c5806).html |
op_rights |
info:eu-repo/semantics/restrictedAccess |
op_doi |
https://doi.org/10.1111/mec.12260 |
container_title |
Molecular Ecology |
container_volume |
22 |
container_issue |
9 |
container_start_page |
2424 |
op_container_end_page |
2440 |
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1785578810068959232 |