The Nordic countries as a cohort for pharmacoepidemiological research
Udgivelsesdato: 2010-Feb The Nordic countries have a long tradition of registry-based epidemiological research. Many population-based health registries were established in the 1960s, with use of unique personal identifiers facilitating linkage between registries. In recent years, each country has es...
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ftuniaarhuspubl:oai:pure.atira.dk:publications/ad00e1b0-2b6d-11df-9806-000ea68e967b 2024-05-19T07:42:44+00:00 The Nordic countries as a cohort for pharmacoepidemiological research Furu, Kari Wettermark, Björn Andersen, Morten Martikainen, Jaana E Almarsdottir, Anna Birna Sørensen, Henrik Toft 2010 https://pure.au.dk/portal/en/publications/ad00e1b0-2b6d-11df-9806-000ea68e967b https://doi.org/10.1111/j.1742-7843.2009.00494.x eng eng https://pure.au.dk/portal/en/publications/ad00e1b0-2b6d-11df-9806-000ea68e967b info:eu-repo/semantics/restrictedAccess Furu , K , Wettermark , B , Andersen , M , Martikainen , J E , Almarsdottir , A B & Sørensen , H T 2010 , ' The Nordic countries as a cohort for pharmacoepidemiological research ' , Basic & Clinical Pharmacology & Toxicology , vol. 106 , no. 2 , pp. 86-94 . https://doi.org/10.1111/j.1742-7843.2009.00494.x Databases Factual Drug Utilization Finland Humans Iceland Medical Record Linkage Pharmacoepidemiology Prescription Drugs Registries Research Scandinavia article 2010 ftuniaarhuspubl https://doi.org/10.1111/j.1742-7843.2009.00494.x 2024-05-01T23:42:47Z Udgivelsesdato: 2010-Feb The Nordic countries have a long tradition of registry-based epidemiological research. Many population-based health registries were established in the 1960s, with use of unique personal identifiers facilitating linkage between registries. In recent years, each country has established a national database to track prescription drugs dispensed to individuals in ambulatory care. The objectives were to present an overview of the prescription databases established in the Nordic countries, as well as to elaborate on their unique potential for record linkage and cross-national comparison of drug utilization. Five Nordic countries collect drug exposure data based on drugs dispensed at pharmacies and have the potential to link these data to health outcomes. The databases together cover 25 million inhabitants (Denmark: 5.5 million; Finland: 5.3 million; Iceland: 0.3 million; Norway: 4.8 million; and Sweden: 9.2 million). In 2007, the registries encompassed 17 million prescription drug users (68% of the total population). We provide examples of how these databases have been used for descriptive drug utilization studies and analytical pharmacoepidemiological studies linking drug exposure to other health registries. Comparisons are facilitated by many similarities among the databases, including data source, content, coverage and methods used for drug utilization studies and record linkage. There are, however, some differences in coding systems and validity, as well as in some access and technical issues. To perform cross-national pharmacoepidemiological studies, resources, networks and time are needed, as well as methods for pooling data. Interpretation of results needs to account for inter-country heterogeneity and the possibility of spurious relationships. The Nordic countries have a unique potential for collaborative high-quality cross-national pharmacoepidemiological studies with large populations. This research may assist in resolving safety issues of international interest, thus minimizing the ... Article in Journal/Newspaper Iceland Aarhus University: Research Basic & Clinical Pharmacology & Toxicology 106 2 86 94 |
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Open Polar |
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Aarhus University: Research |
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ftuniaarhuspubl |
language |
English |
topic |
Databases Factual Drug Utilization Finland Humans Iceland Medical Record Linkage Pharmacoepidemiology Prescription Drugs Registries Research Scandinavia |
spellingShingle |
Databases Factual Drug Utilization Finland Humans Iceland Medical Record Linkage Pharmacoepidemiology Prescription Drugs Registries Research Scandinavia Furu, Kari Wettermark, Björn Andersen, Morten Martikainen, Jaana E Almarsdottir, Anna Birna Sørensen, Henrik Toft The Nordic countries as a cohort for pharmacoepidemiological research |
topic_facet |
Databases Factual Drug Utilization Finland Humans Iceland Medical Record Linkage Pharmacoepidemiology Prescription Drugs Registries Research Scandinavia |
description |
Udgivelsesdato: 2010-Feb The Nordic countries have a long tradition of registry-based epidemiological research. Many population-based health registries were established in the 1960s, with use of unique personal identifiers facilitating linkage between registries. In recent years, each country has established a national database to track prescription drugs dispensed to individuals in ambulatory care. The objectives were to present an overview of the prescription databases established in the Nordic countries, as well as to elaborate on their unique potential for record linkage and cross-national comparison of drug utilization. Five Nordic countries collect drug exposure data based on drugs dispensed at pharmacies and have the potential to link these data to health outcomes. The databases together cover 25 million inhabitants (Denmark: 5.5 million; Finland: 5.3 million; Iceland: 0.3 million; Norway: 4.8 million; and Sweden: 9.2 million). In 2007, the registries encompassed 17 million prescription drug users (68% of the total population). We provide examples of how these databases have been used for descriptive drug utilization studies and analytical pharmacoepidemiological studies linking drug exposure to other health registries. Comparisons are facilitated by many similarities among the databases, including data source, content, coverage and methods used for drug utilization studies and record linkage. There are, however, some differences in coding systems and validity, as well as in some access and technical issues. To perform cross-national pharmacoepidemiological studies, resources, networks and time are needed, as well as methods for pooling data. Interpretation of results needs to account for inter-country heterogeneity and the possibility of spurious relationships. The Nordic countries have a unique potential for collaborative high-quality cross-national pharmacoepidemiological studies with large populations. This research may assist in resolving safety issues of international interest, thus minimizing the ... |
format |
Article in Journal/Newspaper |
author |
Furu, Kari Wettermark, Björn Andersen, Morten Martikainen, Jaana E Almarsdottir, Anna Birna Sørensen, Henrik Toft |
author_facet |
Furu, Kari Wettermark, Björn Andersen, Morten Martikainen, Jaana E Almarsdottir, Anna Birna Sørensen, Henrik Toft |
author_sort |
Furu, Kari |
title |
The Nordic countries as a cohort for pharmacoepidemiological research |
title_short |
The Nordic countries as a cohort for pharmacoepidemiological research |
title_full |
The Nordic countries as a cohort for pharmacoepidemiological research |
title_fullStr |
The Nordic countries as a cohort for pharmacoepidemiological research |
title_full_unstemmed |
The Nordic countries as a cohort for pharmacoepidemiological research |
title_sort |
nordic countries as a cohort for pharmacoepidemiological research |
publishDate |
2010 |
url |
https://pure.au.dk/portal/en/publications/ad00e1b0-2b6d-11df-9806-000ea68e967b https://doi.org/10.1111/j.1742-7843.2009.00494.x |
genre |
Iceland |
genre_facet |
Iceland |
op_source |
Furu , K , Wettermark , B , Andersen , M , Martikainen , J E , Almarsdottir , A B & Sørensen , H T 2010 , ' The Nordic countries as a cohort for pharmacoepidemiological research ' , Basic & Clinical Pharmacology & Toxicology , vol. 106 , no. 2 , pp. 86-94 . https://doi.org/10.1111/j.1742-7843.2009.00494.x |
op_relation |
https://pure.au.dk/portal/en/publications/ad00e1b0-2b6d-11df-9806-000ea68e967b |
op_rights |
info:eu-repo/semantics/restrictedAccess |
op_doi |
https://doi.org/10.1111/j.1742-7843.2009.00494.x |
container_title |
Basic & Clinical Pharmacology & Toxicology |
container_volume |
106 |
container_issue |
2 |
container_start_page |
86 |
op_container_end_page |
94 |
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1799482422740385792 |