Serum concentrations of polybrominated diphenyl ethers (PBDEs) and a polybrominated biphenyl (PBB) in men from Greenland, Poland and Ukraine
Many brominated flame retardants (BFRs)-including polybrominated diphenyl ethers (PBDEs)-have been shown to persist in the environment, and some have been associated with adverse health effects. The aim of the present study was to quantify serum concentrations of common brominated flame retardants i...
Published in: | Environment International |
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Online Access: | https://pure.au.dk/portal/da/publications/serum-concentrations-of-polybrominated-diphenyl-ethers-pbdes-and-a-polybrominated-biphenyl-pbb-in-men-from-greenland-poland-and-ukraine(6b170eea-f819-429e-9f08-b127ee8a949b).html https://doi.org/10.1016/j.envint.2013.09.001 |
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ftuniaarhuspubl:oai:pure.atira.dk:publications/6b170eea-f819-429e-9f08-b127ee8a949b 2023-05-15T16:26:18+02:00 Serum concentrations of polybrominated diphenyl ethers (PBDEs) and a polybrominated biphenyl (PBB) in men from Greenland, Poland and Ukraine Lenters, Virissa Thomsen, Cathrine Smit, Lidwien A M Jönsson, Bo A G Pedersen, Henning S Ludwicki, Jan K Zviezdai, Valentyna Piersma, Aldert H Toft, Gunnar Bonde, Jens Peter Becher, Georg Vermeulen, Roel Heederik, Dick 2013-11 https://pure.au.dk/portal/da/publications/serum-concentrations-of-polybrominated-diphenyl-ethers-pbdes-and-a-polybrominated-biphenyl-pbb-in-men-from-greenland-poland-and-ukraine(6b170eea-f819-429e-9f08-b127ee8a949b).html https://doi.org/10.1016/j.envint.2013.09.001 eng eng info:eu-repo/semantics/restrictedAccess Lenters , V , Thomsen , C , Smit , L A M , Jönsson , B A G , Pedersen , H S , Ludwicki , J K , Zviezdai , V , Piersma , A H , Toft , G , Bonde , J P , Becher , G , Vermeulen , R & Heederik , D 2013 , ' Serum concentrations of polybrominated diphenyl ethers (PBDEs) and a polybrominated biphenyl (PBB) in men from Greenland, Poland and Ukraine ' , Environment International , vol. 61 , pp. 8-16 . https://doi.org/10.1016/j.envint.2013.09.001 Adult Environmental Monitoring Environmental Pollutants Flame Retardants Gas Chromatography-Mass Spectrometry Greenland Halogenated Diphenyl Ethers Humans Male Middle Aged Poland Polybrominated Biphenyls Ukraine Young Adult article 2013 ftuniaarhuspubl https://doi.org/10.1016/j.envint.2013.09.001 2022-11-23T23:54:17Z Many brominated flame retardants (BFRs)-including polybrominated diphenyl ethers (PBDEs)-have been shown to persist in the environment, and some have been associated with adverse health effects. The aim of the present study was to quantify serum concentrations of common brominated flame retardants in Inuit men from across Greenland, and in men from Warsaw, Poland and Kharkiv, Ukraine. Serum was sampled between 2002 and 2004 from men 19 to 50years of age. 299 samples were analyzed for BDE-28, 47, 99, 100, 153, 154 and 183 and the brominated biphenyl BB-153 using gas chromatography-high resolution mass spectrometry. BDE-47 and BDE-153 were detected in more than 95% of samples from all three populations. All other congeners, except BDE-154, were detected in more than 70% of samples from Greenland; lower detection frequencies were observed in Polish and Ukrainian samples. Concentrations of individual congeners were 2.7 to 15 fold higher in Greenlandic relative to Polish and Ukrainian men. Geometric mean concentrations of the sum of the most abundant PBDEs of the Penta-BDE commercial mixture (BDE-47, 99, 100, 153 and 154) were 6.1, 1.7 and 0.87ng/g lipids in the Greenlandic, Polish and Ukrainian men, respectively. Furthermore, significant geographical differences in BFR concentrations were observed within Greenland. Principal component analysis revealed distinct clustering of samples by country of origin. The associations between ΣPBDEs and age were inconsistent, varying from no association in Greenlandic and Polish study populations to a U-shaped relationship in Ukrainians. We report BFR levels for three populations for which sparse biomonitoring data exists. Article in Journal/Newspaper Greenland greenlandic inuit Aarhus University: Research Greenland Environment International 61 8 16 |
institution |
Open Polar |
collection |
Aarhus University: Research |
op_collection_id |
ftuniaarhuspubl |
language |
English |
topic |
Adult Environmental Monitoring Environmental Pollutants Flame Retardants Gas Chromatography-Mass Spectrometry Greenland Halogenated Diphenyl Ethers Humans Male Middle Aged Poland Polybrominated Biphenyls Ukraine Young Adult |
spellingShingle |
Adult Environmental Monitoring Environmental Pollutants Flame Retardants Gas Chromatography-Mass Spectrometry Greenland Halogenated Diphenyl Ethers Humans Male Middle Aged Poland Polybrominated Biphenyls Ukraine Young Adult Lenters, Virissa Thomsen, Cathrine Smit, Lidwien A M Jönsson, Bo A G Pedersen, Henning S Ludwicki, Jan K Zviezdai, Valentyna Piersma, Aldert H Toft, Gunnar Bonde, Jens Peter Becher, Georg Vermeulen, Roel Heederik, Dick Serum concentrations of polybrominated diphenyl ethers (PBDEs) and a polybrominated biphenyl (PBB) in men from Greenland, Poland and Ukraine |
topic_facet |
Adult Environmental Monitoring Environmental Pollutants Flame Retardants Gas Chromatography-Mass Spectrometry Greenland Halogenated Diphenyl Ethers Humans Male Middle Aged Poland Polybrominated Biphenyls Ukraine Young Adult |
description |
Many brominated flame retardants (BFRs)-including polybrominated diphenyl ethers (PBDEs)-have been shown to persist in the environment, and some have been associated with adverse health effects. The aim of the present study was to quantify serum concentrations of common brominated flame retardants in Inuit men from across Greenland, and in men from Warsaw, Poland and Kharkiv, Ukraine. Serum was sampled between 2002 and 2004 from men 19 to 50years of age. 299 samples were analyzed for BDE-28, 47, 99, 100, 153, 154 and 183 and the brominated biphenyl BB-153 using gas chromatography-high resolution mass spectrometry. BDE-47 and BDE-153 were detected in more than 95% of samples from all three populations. All other congeners, except BDE-154, were detected in more than 70% of samples from Greenland; lower detection frequencies were observed in Polish and Ukrainian samples. Concentrations of individual congeners were 2.7 to 15 fold higher in Greenlandic relative to Polish and Ukrainian men. Geometric mean concentrations of the sum of the most abundant PBDEs of the Penta-BDE commercial mixture (BDE-47, 99, 100, 153 and 154) were 6.1, 1.7 and 0.87ng/g lipids in the Greenlandic, Polish and Ukrainian men, respectively. Furthermore, significant geographical differences in BFR concentrations were observed within Greenland. Principal component analysis revealed distinct clustering of samples by country of origin. The associations between ΣPBDEs and age were inconsistent, varying from no association in Greenlandic and Polish study populations to a U-shaped relationship in Ukrainians. We report BFR levels for three populations for which sparse biomonitoring data exists. |
format |
Article in Journal/Newspaper |
author |
Lenters, Virissa Thomsen, Cathrine Smit, Lidwien A M Jönsson, Bo A G Pedersen, Henning S Ludwicki, Jan K Zviezdai, Valentyna Piersma, Aldert H Toft, Gunnar Bonde, Jens Peter Becher, Georg Vermeulen, Roel Heederik, Dick |
author_facet |
Lenters, Virissa Thomsen, Cathrine Smit, Lidwien A M Jönsson, Bo A G Pedersen, Henning S Ludwicki, Jan K Zviezdai, Valentyna Piersma, Aldert H Toft, Gunnar Bonde, Jens Peter Becher, Georg Vermeulen, Roel Heederik, Dick |
author_sort |
Lenters, Virissa |
title |
Serum concentrations of polybrominated diphenyl ethers (PBDEs) and a polybrominated biphenyl (PBB) in men from Greenland, Poland and Ukraine |
title_short |
Serum concentrations of polybrominated diphenyl ethers (PBDEs) and a polybrominated biphenyl (PBB) in men from Greenland, Poland and Ukraine |
title_full |
Serum concentrations of polybrominated diphenyl ethers (PBDEs) and a polybrominated biphenyl (PBB) in men from Greenland, Poland and Ukraine |
title_fullStr |
Serum concentrations of polybrominated diphenyl ethers (PBDEs) and a polybrominated biphenyl (PBB) in men from Greenland, Poland and Ukraine |
title_full_unstemmed |
Serum concentrations of polybrominated diphenyl ethers (PBDEs) and a polybrominated biphenyl (PBB) in men from Greenland, Poland and Ukraine |
title_sort |
serum concentrations of polybrominated diphenyl ethers (pbdes) and a polybrominated biphenyl (pbb) in men from greenland, poland and ukraine |
publishDate |
2013 |
url |
https://pure.au.dk/portal/da/publications/serum-concentrations-of-polybrominated-diphenyl-ethers-pbdes-and-a-polybrominated-biphenyl-pbb-in-men-from-greenland-poland-and-ukraine(6b170eea-f819-429e-9f08-b127ee8a949b).html https://doi.org/10.1016/j.envint.2013.09.001 |
geographic |
Greenland |
geographic_facet |
Greenland |
genre |
Greenland greenlandic inuit |
genre_facet |
Greenland greenlandic inuit |
op_source |
Lenters , V , Thomsen , C , Smit , L A M , Jönsson , B A G , Pedersen , H S , Ludwicki , J K , Zviezdai , V , Piersma , A H , Toft , G , Bonde , J P , Becher , G , Vermeulen , R & Heederik , D 2013 , ' Serum concentrations of polybrominated diphenyl ethers (PBDEs) and a polybrominated biphenyl (PBB) in men from Greenland, Poland and Ukraine ' , Environment International , vol. 61 , pp. 8-16 . https://doi.org/10.1016/j.envint.2013.09.001 |
op_rights |
info:eu-repo/semantics/restrictedAccess |
op_doi |
https://doi.org/10.1016/j.envint.2013.09.001 |
container_title |
Environment International |
container_volume |
61 |
container_start_page |
8 |
op_container_end_page |
16 |
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1766015208400093184 |