Genome-wide analyses suggest parallel selection for universal traits may eclipse local environmental selection in a highly mobile carnivore
Ecological and environmental heterogeneity can produce genetic differentiation in highly mobile species. Accordingly, local adaptation may be expected across comparatively short distances in the presence of marked environmental gradients. Within the European continent, wolves (Canis lupus) exhibit d...
Published in: | Ecology and Evolution |
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ftuniaarhuspubl:oai:pure.atira.dk:publications/318950d6-c8f4-4eca-8f87-9a783c794bdf 2023-12-17T10:28:35+01:00 Genome-wide analyses suggest parallel selection for universal traits may eclipse local environmental selection in a highly mobile carnivore Stronen, Astrid Vik Jedrzejewska, Bogumiła Pertoldi, Cino Demontis, Ditte Randi, Ettore Niedziałkowska, Magdalena Borowik, Tomasz Sidorovich, Vadim E. Kusak, Josip Kojola, Ilpo Karamanlidis, Alexandros A. Ozolins, Janis Dumenko, Vitalii Czarnomska, Sylwia D. 2015-10-01 https://pure.au.dk/portal/da/publications/genomewide-analyses-suggest-parallel-selection-for-universal-traits-may-eclipse-local-environmental-selection-in-a-highly-mobile-carnivore(318950d6-c8f4-4eca-8f87-9a783c794bdf).html https://doi.org/10.1002/ece3.1695 http://www.scopus.com/inward/record.url?scp=84942846447&partnerID=8YFLogxK eng eng https://pure.au.dk/portal/da/publications/genomewide-analyses-suggest-parallel-selection-for-universal-traits-may-eclipse-local-environmental-selection-in-a-highly-mobile-carnivore(318950d6-c8f4-4eca-8f87-9a783c794bdf).html info:eu-repo/semantics/openAccess Stronen , A V , Jedrzejewska , B , Pertoldi , C , Demontis , D , Randi , E , Niedziałkowska , M , Borowik , T , Sidorovich , V E , Kusak , J , Kojola , I , Karamanlidis , A A , Ozolins , J , Dumenko , V & Czarnomska , S D 2015 , ' Genome-wide analyses suggest parallel selection for universal traits may eclipse local environmental selection in a highly mobile carnivore ' , Ecology and Evolution , vol. 5 , no. 19 , pp. 4410-4425 . https://doi.org/10.1002/ece3.1695 CanineHD BeadChip microarray Canis lupus Environmental selection Genome-wide association study Single nucleotide polymorphism Wolf article 2015 ftuniaarhuspubl https://doi.org/10.1002/ece3.1695 2023-11-23T00:00:48Z Ecological and environmental heterogeneity can produce genetic differentiation in highly mobile species. Accordingly, local adaptation may be expected across comparatively short distances in the presence of marked environmental gradients. Within the European continent, wolves (Canis lupus) exhibit distinct north-south population differentiation. We investigated more than 67-K single nucleotide polymorphism (SNP) loci for signatures of local adaptation in 59 unrelated wolves from four previously identified population clusters (northcentral Europe n = 32, Carpathian Mountains n = 7, Dinaric-Balkan n = 9, Ukrainian Steppe n = 11). Our analyses combined identification of outlier loci with findings from genome-wide association study of individual genomic profiles and 12 environmental variables. We identified 353 candidate SNP loci. We examined the SNP position and neighboring megabase (1 Mb, one million bases) regions in the dog (C. lupus familiaris) genome for genes potentially under selection, including homologue genes in other vertebrates. These regions included functional genes for, for example, temperature regulation that may indicate local adaptation and genes controlling for functions universally important for wolves, including olfaction, hearing, vision, and cognitive functions. We also observed strong outliers not associated with any of the investigated variables, which could suggest selective pressures associated with other unmeasured environmental variables and/or demographic factors. These patterns are further supported by the examination of spatial distributions of the SNPs associated with universally important traits, which typically show marked differences in allele frequencies among population clusters. Accordingly, parallel selection for features important to all wolves may eclipse local environmental selection and implies long-term separation among population clusters. Article in Journal/Newspaper Canis lupus Aarhus University: Research Ecology and Evolution 5 19 4410 4425 |
institution |
Open Polar |
collection |
Aarhus University: Research |
op_collection_id |
ftuniaarhuspubl |
language |
English |
topic |
CanineHD BeadChip microarray Canis lupus Environmental selection Genome-wide association study Single nucleotide polymorphism Wolf |
spellingShingle |
CanineHD BeadChip microarray Canis lupus Environmental selection Genome-wide association study Single nucleotide polymorphism Wolf Stronen, Astrid Vik Jedrzejewska, Bogumiła Pertoldi, Cino Demontis, Ditte Randi, Ettore Niedziałkowska, Magdalena Borowik, Tomasz Sidorovich, Vadim E. Kusak, Josip Kojola, Ilpo Karamanlidis, Alexandros A. Ozolins, Janis Dumenko, Vitalii Czarnomska, Sylwia D. Genome-wide analyses suggest parallel selection for universal traits may eclipse local environmental selection in a highly mobile carnivore |
topic_facet |
CanineHD BeadChip microarray Canis lupus Environmental selection Genome-wide association study Single nucleotide polymorphism Wolf |
description |
Ecological and environmental heterogeneity can produce genetic differentiation in highly mobile species. Accordingly, local adaptation may be expected across comparatively short distances in the presence of marked environmental gradients. Within the European continent, wolves (Canis lupus) exhibit distinct north-south population differentiation. We investigated more than 67-K single nucleotide polymorphism (SNP) loci for signatures of local adaptation in 59 unrelated wolves from four previously identified population clusters (northcentral Europe n = 32, Carpathian Mountains n = 7, Dinaric-Balkan n = 9, Ukrainian Steppe n = 11). Our analyses combined identification of outlier loci with findings from genome-wide association study of individual genomic profiles and 12 environmental variables. We identified 353 candidate SNP loci. We examined the SNP position and neighboring megabase (1 Mb, one million bases) regions in the dog (C. lupus familiaris) genome for genes potentially under selection, including homologue genes in other vertebrates. These regions included functional genes for, for example, temperature regulation that may indicate local adaptation and genes controlling for functions universally important for wolves, including olfaction, hearing, vision, and cognitive functions. We also observed strong outliers not associated with any of the investigated variables, which could suggest selective pressures associated with other unmeasured environmental variables and/or demographic factors. These patterns are further supported by the examination of spatial distributions of the SNPs associated with universally important traits, which typically show marked differences in allele frequencies among population clusters. Accordingly, parallel selection for features important to all wolves may eclipse local environmental selection and implies long-term separation among population clusters. |
format |
Article in Journal/Newspaper |
author |
Stronen, Astrid Vik Jedrzejewska, Bogumiła Pertoldi, Cino Demontis, Ditte Randi, Ettore Niedziałkowska, Magdalena Borowik, Tomasz Sidorovich, Vadim E. Kusak, Josip Kojola, Ilpo Karamanlidis, Alexandros A. Ozolins, Janis Dumenko, Vitalii Czarnomska, Sylwia D. |
author_facet |
Stronen, Astrid Vik Jedrzejewska, Bogumiła Pertoldi, Cino Demontis, Ditte Randi, Ettore Niedziałkowska, Magdalena Borowik, Tomasz Sidorovich, Vadim E. Kusak, Josip Kojola, Ilpo Karamanlidis, Alexandros A. Ozolins, Janis Dumenko, Vitalii Czarnomska, Sylwia D. |
author_sort |
Stronen, Astrid Vik |
title |
Genome-wide analyses suggest parallel selection for universal traits may eclipse local environmental selection in a highly mobile carnivore |
title_short |
Genome-wide analyses suggest parallel selection for universal traits may eclipse local environmental selection in a highly mobile carnivore |
title_full |
Genome-wide analyses suggest parallel selection for universal traits may eclipse local environmental selection in a highly mobile carnivore |
title_fullStr |
Genome-wide analyses suggest parallel selection for universal traits may eclipse local environmental selection in a highly mobile carnivore |
title_full_unstemmed |
Genome-wide analyses suggest parallel selection for universal traits may eclipse local environmental selection in a highly mobile carnivore |
title_sort |
genome-wide analyses suggest parallel selection for universal traits may eclipse local environmental selection in a highly mobile carnivore |
publishDate |
2015 |
url |
https://pure.au.dk/portal/da/publications/genomewide-analyses-suggest-parallel-selection-for-universal-traits-may-eclipse-local-environmental-selection-in-a-highly-mobile-carnivore(318950d6-c8f4-4eca-8f87-9a783c794bdf).html https://doi.org/10.1002/ece3.1695 http://www.scopus.com/inward/record.url?scp=84942846447&partnerID=8YFLogxK |
genre |
Canis lupus |
genre_facet |
Canis lupus |
op_source |
Stronen , A V , Jedrzejewska , B , Pertoldi , C , Demontis , D , Randi , E , Niedziałkowska , M , Borowik , T , Sidorovich , V E , Kusak , J , Kojola , I , Karamanlidis , A A , Ozolins , J , Dumenko , V & Czarnomska , S D 2015 , ' Genome-wide analyses suggest parallel selection for universal traits may eclipse local environmental selection in a highly mobile carnivore ' , Ecology and Evolution , vol. 5 , no. 19 , pp. 4410-4425 . https://doi.org/10.1002/ece3.1695 |
op_relation |
https://pure.au.dk/portal/da/publications/genomewide-analyses-suggest-parallel-selection-for-universal-traits-may-eclipse-local-environmental-selection-in-a-highly-mobile-carnivore(318950d6-c8f4-4eca-8f87-9a783c794bdf).html |
op_rights |
info:eu-repo/semantics/openAccess |
op_doi |
https://doi.org/10.1002/ece3.1695 |
container_title |
Ecology and Evolution |
container_volume |
5 |
container_issue |
19 |
container_start_page |
4410 |
op_container_end_page |
4425 |
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1785580725093793792 |